State of the Art Review on Emerging Applications of Mesoporous Silica

The recent advances in the drug delivery system using a variety of technological platforms have resulted in innovation in the attitude towards diagnosis and therapeutics alike in the present times. Mesoporous Silica possesses favourable chemical properties, thermal stability, and biocompatibility. The unique structure of mesoporous silica makes possible the effective loading of drugs and their subsequent release in a controlled manner at the target site. The properties like pore size, high drug loading, and porosity as well as the surface properties of Mesoporous silica make them a suitable platform for many drug delivery applications. This review focuses on the applications and the advances made in the mesoporous silica to broaden the spectrum of its use especially in the field of medicine. The Mesoporous Silica carrier has proved its use in the field of biosensing, controlled and targeted drug release, gene delivery, water treatment, solubility and bioavailability enhancement and wound healing.

Nanomedical Devices and Cancer Theranostics

The current therapies against cancer showed limited success. Nanotechnology is a promising strategy for cancer tracking, diagnosis, and therapy. The hybrid nanotechnology assembled several materials in a multimodal system to develop multifunctional approaches to cancer treatment. The quantum dot and polymer are some of these hybrid nanoparticle platforms. The quantum dot hybrid system possesses photonic and magnetic properties, allowing photothermal therapy and live multimodal imaging of cancer. These quantum dots were used to convey medicines to cancer cells. Hybrid polymer nanoparticles were utilized for the systemic delivery of small interfering RNA to malignant tumors and metastasis. They allowed non-invasive imaging to track in real-time the biodistribution of small interfering RNA in the whole body. They offer an opportunity to treat cancers by specifically silencing target genes. This review highlights the major nanotechnology approaches to effectively treat cancer and metastasis.