Effects of Irradiation on Synthesis of Deoxyribonucleic Acid and Mitosis in Synchronous Cultures of Hela Cells

Nature ◽  
1966 ◽  
Vol 210 (5034) ◽  
pp. 393-395 ◽  
Author(s):  
T. P. BRENT ◽  
J. A. V. BUTLER ◽  
A. R. CRATHORN
Keyword(s):  
Hela Cells ◽  
Deoxyribonucleic Acid ◽  
Synchronous Cultures ◽  
Effects Of Irradiation On

BIOCHEMICAL EFFECTS OF IRRADIATION ON LIVER REGENERATION

1960 ◽  
Vol 38 (10) ◽  
pp. 1059-1068 ◽  
Author(s):  
D. K. Myers
Keyword(s):  
Deoxyribonucleic Acid ◽  
Normal Liver ◽  
Cell Nuclei ◽  
Local Irradiation ◽  
Biochemical Effects ◽  
Marked Accumulation ◽  
Liver Region ◽  
Rat Livers ◽  
Weight Number ◽  
Effects Of Irradiation On

Little change in the total weight, number of cell nuclei, and amounts of protein, ribonucleic acid, and deoxyribonucleic acid occurs in rat livers after local irradiation of the liver region. However, irradiation of the normal liver before partial hepatectomy does retard subsequent DNA accumulation and increase in number of cell nuclei. These effects appear to be due to a localized action of the radiation on the liver cells. The lag in DNA accumulation is not accompanied by a marked accumulation of acid-soluble purine–deoxyribose derivatives.

Deoxyribonucleic acid chain growth and organization of replicating units in HeLa cells

Biochemistry ◽  
1977 ◽  
Vol 16 (9) ◽  
pp. 1808-1813 ◽  
Author(s):  
Stephen R. Planck ◽  
Gerald C. Mueller
Keyword(s):  
Hela Cells ◽  
Deoxyribonucleic Acid ◽  
Chain Growth

scholarly journals Study upon The Tritiated Thymidine Incorporation into Deoxyribonucleic Acid of Tissue Cultured HeLa Cells

RADIOISOTOPES ◽  
1961 ◽  
Vol 10 (1) ◽  
pp. 135-139
Author(s):  
Toyozo SEKIGUCHI ◽  
Takako KANKURA ◽  
Hideo ETO ◽  
Tetuo IWAKURA
Keyword(s):  
Hela Cells ◽  
Deoxyribonucleic Acid ◽  
Thymidine Incorporation ◽  
Tritiated Thymidine

BIOCHEMICAL EFFECTS OF IRRADIATION ON LIVER REGENERATION

1960 ◽  
Vol 38 (1) ◽  
pp. 1059-1068 ◽  
Author(s):  
D. K. Myers
Keyword(s):  
Deoxyribonucleic Acid ◽  
Normal Liver ◽  
Cell Nuclei ◽  
Local Irradiation ◽  
Biochemical Effects ◽  
Marked Accumulation ◽  
Liver Region ◽  
Rat Livers ◽  
Weight Number ◽  
Effects Of Irradiation On

Little change in the total weight, number of cell nuclei, and amounts of protein, ribonucleic acid, and deoxyribonucleic acid occurs in rat livers after local irradiation of the liver region. However, irradiation of the normal liver before partial hepatectomy does retard subsequent DNA accumulation and increase in number of cell nuclei. These effects appear to be due to a localized action of the radiation on the liver cells. The lag in DNA accumulation is not accompanied by a marked accumulation of acid-soluble purine–deoxyribose derivatives.

scholarly journals A STUDY OF THE PENETRATION OF MAMMALIAN CELLS BY DEOXYRIBONUCLEIC ACIDS

1961 ◽  
Vol 9 (1) ◽  
pp. 81-91 ◽  
Author(s):  
Ellen Borenfreund ◽  
Aaron Bendich
Keyword(s):  
Nucleic Acids ◽  
Hela Cell ◽  
Perchloric Acid ◽  
Hela Cells ◽  
Mammalian Cells ◽  
Deoxyribonucleic Acid ◽  
Degradation Products ◽  
Dna Bases ◽  
Human Dna ◽  
Nuclear Regions

Tritium-labeled deoxyribonucleic acid (DNA) from pneumococci and from human leukocytes was added to growing cultures of HeLa cells at 37°C. Autoradiography revealed an extensive localization of tritium in the nuclear regions. The label could not be removed by treatment with ribonuclease or dilute perchloric acid, but quantitative removal from the cells could be effected with deoxyribonuclease. Chemical and radioactivity determinations on nucleic acids isolated from the exposed HeLa cells revealed the presence of tritium in all 4 DNA bases. About 12 µg. of tritiated DNA was recovered from 6 x 106 HeLa cells which had been exposed for 24 hours to 240 µg. of the human DNA. From this, it is concluded that the amount of DNA, or its degradation products, taken up by the cells was equivalent to at least 10 per cent of the normal HeLa cell complement.

scholarly journals Effect of Poliovirus on Deoxyribonucleic Acid Synthesis in HeLa Cells

1966 ◽  
Vol 91 (5) ◽  
pp. 1943-1952 ◽  
Author(s):  
W. W. Ackermann ◽  
D. C. Cox ◽  
H. Kurtz ◽  
C. D. Powers ◽  
S. J. Davies
Keyword(s):  
Hela Cells ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Deoxyribonucleic Acid Synthesis
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