scholarly journals Age-related associative memory deficits in value-based remembering: The contribution of agenda-based regulation and strategy use.

2015 ◽  
Vol 30 (4) ◽  
pp. 795-808 ◽  
Author(s):  
Robert Ariel ◽  
Jodi Price ◽  
Christopher Hertzog
2016 ◽  
Vol 31 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Andrea C. Smyth ◽  
Moshe Naveh-Benjamin

2012 ◽  
Vol 27 (1) ◽  
pp. 141-152 ◽  
Author(s):  
Stephen P. Badham ◽  
Zachary Estes ◽  
Elizabeth A. Maylor

Author(s):  
Sujeong Yang ◽  
Sylvain Gigout ◽  
Angelo Molinaro ◽  
Yuko Naito-Matsui ◽  
Sam Hilton ◽  
...  

AbstractPerineuronal nets (PNNs) are chondroitin sulphate proteoglycan-containing structures on the neuronal surface that have been implicated in the control of neuroplasticity and memory. Age-related reduction of chondroitin 6-sulphates (C6S) leads to PNNs becoming more inhibitory. Here, we investigated whether manipulation of the chondroitin sulphate (CS) composition of the PNNs could restore neuroplasticity and alleviate memory deficits in aged mice. We first confirmed that aged mice (20-months) showed memory and plasticity deficits. They were able to retain or regain their cognitive ability when CSs were digested or PNNs were attenuated. We then explored the role of C6S in memory and neuroplasticity. Transgenic deletion of chondroitin 6-sulfotransferase (chst3) led to a reduction of permissive C6S, simulating aged brains. These animals showed very early memory loss at 11 weeks old. Importantly, restoring C6S levels in aged animals rescued the memory deficits and restored cortical long-term potentiation, suggesting a strategy to improve age-related memory impairment.


2021 ◽  
Author(s):  
Khushi Patel

Cross-cultural research suggests that individualistic Americans have a tendency to process focal objects; in contrast, collectivist Asians have a tendency to bind objects and context (Park & Huang, 2010). However, little is known whether the reported cultural differences are moderated by cultural orientation. In light of these results and the well-reported age-related decline in binding abilities, the current study examined cultural and age differences in cultural orientation, spatial memory and strategy use with young and older Canadian and Indian adults. There was little difference between Canadian and Indian participants’ cultural orientation. While cultural orientation did not moderate the relationship between culture and spatial memory, spatial memory and strategy use differed as a function of age. The use of context-specific strategies resulted in performance gains in older adults, however overall older adults had poor spatial memory, with Indian older adults scoring significantly lower than Canadian older adults on the courtyard task.


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