Copolymers of Aniline and 3-Aminophenol Derivatives with Oligo(oxyethylene) Side Chains as Novel Water-Soluble Conducting Polymers

2004 ◽  
Vol 37 (16) ◽  
pp. 6104-6112 ◽  
Author(s):  
Fengjun Hua ◽  
Eli Ruckenstein
2021 ◽  
Author(s):  
Thanh Huong Truong ◽  
Lenka Musilová ◽  
Věra Kašpárková ◽  
Daniela Jasenská ◽  
Petr Ponížil ◽  
...  

Abstract Novel bio-inspired conductive scaffolds composed of sodium hyaluronate containing water soluble polyaniline or polypyrrole colloidal particles (concentrations 0.108, 0.054 and 0.036 % w/w) were manufactured. For this purpose, either crosslinking with N-(3-dimethylaminopropyl-N-ethylcarbodiimide hydrochloride and N-hydroxysuccinimid or a freeze-thawing process in the presence of poly(vinylalcohol) were used. The scaffolds comprised interconnected pores with prevailing porosity values of ~30 % and pore sizes enabling the accommodation of cells. Good swelling capacity (92 – 97 %) without any sign of disintegration was typical for all samples. The elasticity modulus depended on the composition of the scaffolds, with the highest value of ~50 000 Pa obtained for the sample containing the highest content of polypyrrole particles. The scaffolds did not possess cytotoxicity and allowed cell adhesion and growth on the surface. Using the in vivo-mimicking conditions in a bioreactor, cells were also able to grow into the structure of the scaffolds. The technique of scaffold preparation used here thus overcomes the limitations of conducting polymers (e.g. poor solubility in an aqueous environment, and limited miscibility with other hydrophilic polymer matrices) and moreover leads to the preparation of cytocompatible scaffolds with potentially cell-instructive properties, which may be of advantage in the healing of damaged electro-sensitive tissues.


2020 ◽  
Vol 56 (74) ◽  
pp. 10914-10917
Author(s):  
Isao Yamaguchi ◽  
Ryoga Ooe ◽  
Aohan Wang

Soft materials for telomere DNA length sensing were developed.


2016 ◽  
Author(s):  
Ferdinando F. Bruno ◽  
Manuele Bernabei

2015 ◽  
Vol 68 (4) ◽  
pp. 543 ◽  
Author(s):  
Mark Gregory ◽  
Meng-Xin Yin ◽  
Malcolm J. McConville ◽  
Eleanor Williams ◽  
Alex N. Bullock ◽  
...  

Phosphatidylinositol phosphates are key regulators of cell signalling pathways and membrane trafficking in eukaryotic cells, and there is a need for new chemical probes to further understand how they interact with lipid-binding proteins. Here, the synthesis of phosphatidylinositol phosphate analogues containing adamantyl carboxylic ester groups, in place of the natural lipid side chains, is described. These derivatives are considerably more soluble in water than analogues containing other lipid side chains and do not form large aggregates such as liposomes or micelles. These adamantyl analogues bind to known phosphoinositide-binding proteins with similar affinities to native ligands and will facilitate future studies on the substrate specificities of these proteins involving cocrystallisation studies with proteins.


2014 ◽  
Vol 15 (6) ◽  
pp. 1290-1298 ◽  
Author(s):  
Seung-Hoon Lee ◽  
Seung-Hwan Oh ◽  
Yongsung Ji ◽  
Juhwan Kim ◽  
Rira Kang ◽  
...  

1997 ◽  
Vol 30 (18) ◽  
pp. 5553-5556 ◽  
Author(s):  
Čestmír Koňák ◽  
Ramesh C. Rathi ◽  
Pavla Kopečková ◽  
Jindřich Kopeček
Keyword(s):  

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