High Density Orthogonal Surface Immobilization via Photoactivated Copper-Free Click Chemistry

2010 ◽  
Vol 132 (32) ◽  
pp. 11024-11026 ◽  
Author(s):  
Sara V. Orski ◽  
Andrei A. Poloukhtine ◽  
Selvanathan Arumugam ◽  
Leidong Mao ◽  
Vladimir V. Popik ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Density ◽  
Surface Immobilization ◽  
Orthogonal Surface

scholarly journals Fabrication of Low-Fouling Surfaces on Alkyne-Functionalized Poly-(p-xylylenes) Using Click Chemistry

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 225
Author(s):  
Pei-Ju Chen ◽  
Hsien-Yeh Chen ◽  
Wei-Bor Tsai
Keyword(s):  
Thin Films ◽  
Conjugated Polymers ◽  
Click Chemistry ◽  
Vapor Deposition ◽  
Chemical Vapor ◽  
Universal Method ◽  
Surface Immobilization ◽  
Poly Ethylene Glycol ◽  
Wide Range ◽  
Poly Ethylene

A facial, versatile, and universal method that breaks the substrate limits is desirable for antifouling treatment. Thin films of functional poly-p-xylylenes (PPX) that are deposited using chemical vapor deposition (CVD) provide a powerful platform for surface immobilization of molecules. In this study, we prepared an alkyne-functionalized PPX coating on which poly (sulfobetaine methacrylate-co-Az) could be conjugated via click chemistry. We found that the conjugated polymers were very stable and inhibited cell adhesion and protein adsorption effectively. The same conjugation strategy could also be applied to conjugate azide-containing poly (ethylene glycol) and poly (NIPAAm). The results indicate that our method provides a simple and robust tool for fabricating antifouling surfaces on a wide range of substrates using CVD technology of functionalized poly (p-xylylenes) for biosensor, diagnostics, immunoassay, and other biomaterial applications.

A cascade surface immobilization strategy to access high-density and closely distanced atomic Pt sites for enhancing alkaline hydrogen evolution reaction

2020 ◽  
Vol 8 (10) ◽  
pp. 5255-5262 ◽  
Author(s):  
Wenping Liu ◽  
Jing Ji ◽  
Xuecheng Yan ◽  
Wenbo Liu ◽  
Yu-Cheng Huang ◽  
...  
Keyword(s):  
Hydrogen Evolution ◽  
Hydrogen Evolution Reaction ◽  
Metal Catalysts ◽  
High Density ◽  
Pt Catalysts ◽  
Surface Immobilization ◽  
Synthetic Strategy

A stepwise anchoring synthetic strategy has been developed for the closely-distanced atomic Pt catalysts with superior alkaline HER activity, providing a versatile platform for accessing atomic metal catalysts toward various industrial reactions.

Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA

2006 ◽  
Vol 8 (17) ◽  
pp. 3639-3642 ◽  
Author(s):  
Johannes Gierlich ◽  
Glenn A. Burley ◽  
Philipp M. E. Gramlich ◽  
David M. Hammond ◽  
Thomas Carell
Keyword(s):  
Click Chemistry ◽  
Reliable Method ◽  
High Density ◽  
Modified Dna

High-Density DNA Functionalization by a Combination of Cu-Catalyzed and Cu-Free Click Chemistry

2010 ◽  
Vol 16 (23) ◽  
pp. 6877-6883 ◽  
Author(s):  
Katrin Gutsmiedl ◽  
Danila Fazio ◽  
Thomas Carell
Keyword(s):  
Click Chemistry ◽  
High Density ◽  
Dna Functionalization
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