High density cationic polymer brushes from combined “click chemistry” and RAFT-mediated polymerization

2012 ◽  
Vol 50 (15) ◽  
pp. 2999-3007 ◽  
Author(s):  
Serkan Demirci ◽  
Tuncer Caykara
Keyword(s):  
Click Chemistry ◽  
Polymer Brushes ◽  
Cationic Polymer ◽  
High Density

scholarly journals Self-regenerating giant hyaluronan polymer brushes

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Wenbin Wei ◽  
Jessica L. Faubel ◽  
Hemaa Selvakumar ◽  
Daniel T. Kovari ◽  
Joanna Tsao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Polymer Brushes ◽  
Functional Materials ◽  
Polymer Physics ◽  
High Density ◽  
Hyaluronan Synthase ◽  
Dynamic Interface ◽  
Continuous Source

AbstractTailoring interfaces with polymer brushes is a commonly used strategy to create functional materials for numerous applications. Existing methods are limited in brush thickness, the ability to generate high-density brushes of biopolymers, and the potential for regeneration. Here we introduce a scheme to synthesize ultra-thick regenerating hyaluronan polymer brushes using hyaluronan synthase. The platform provides a dynamic interface with tunable brush heights that extend up to 20 microns – two orders of magnitude thicker than standard brushes. The brushes are easily sculpted into micropatterned landscapes by photo-deactivation of the enzyme. Further, they provide a continuous source of megadalton hyaluronan or they can be covalently-stabilized to the surface. Stabilized brushes exhibit superb resistance to biofilms, yet are locally digested by fibroblasts. This brush technology provides opportunities in a range of arenas including regenerating tailorable biointerfaces for implants, wound healing or lubrication as well as fundamental studies of the glycocalyx and polymer physics.

Highly efficient synthesis of polymer brushes with PEO and PCL as side chains via click chemistry

Polymer ◽  
2012 ◽  
Vol 53 (10) ◽  
pp. 1992-2000 ◽  
Author(s):  
Peng Zhao ◽  
Yechao Yan ◽  
Xiaoqin Feng ◽  
Lixin Liu ◽  
Chun Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Polymer Brushes ◽  
Side Chains ◽  
Efficient Synthesis ◽  
Highly Efficient

Fabrication of Ordered Arrays of Gold Nanoparticles Coated with High-Density Polymer Brushes

2003 ◽  
Vol 42 (24) ◽  
pp. 2751-2754 ◽  
Author(s):  
Kohji Ohno ◽  
Kyoungmoo Koh ◽  
Yoshinobu Tsujii ◽  
Takeshi Fukuda
Keyword(s):  
Gold Nanoparticles ◽  
Polymer Brushes ◽  
High Density ◽  
Ordered Arrays

scholarly journals Highly Stable RNA Capture by Dense Cationic Polymer Brushes for the Design of Cytocompatible, Serum-Stable SiRNA Delivery Vectors

2018 ◽  
Vol 19 (2) ◽  
pp. 606-615 ◽  
Author(s):  
Danyang Li ◽  
Amir S. Sharili ◽  
John Connelly ◽  
Julien E. Gautrot
Keyword(s):  
Polymer Brushes ◽  
Sirna Delivery ◽  
Cationic Polymer

scholarly journals Accessible and sustainable Cu(0)-mediated radical polymerisation for the functionalisation of surfaces

2020 ◽  
Vol 11 (23) ◽  
pp. 3831-3840
Author(s):  
Oliver Frank Uttley ◽  
Leonie Alice Brummitt ◽  
Stephen David Worrall ◽  
Steve Edmondson
Keyword(s):  
Polymer Brushes ◽  
Cationic Polymer ◽  
Environmentally Benign ◽  
Controlled Growth ◽  
Ambient Conditions ◽  
Radical Polymerisation ◽  
Benign Solvents ◽  
Surface Functionalisation

Towards use of environmentally benign solvents and ambient conditions for surface functionalisation by controlled growth of thick cationic polymer brushes.

High Density Orthogonal Surface Immobilization via Photoactivated Copper-Free Click Chemistry

2010 ◽  
Vol 132 (32) ◽  
pp. 11024-11026 ◽  
Author(s):  
Sara V. Orski ◽  
Andrei A. Poloukhtine ◽  
Selvanathan Arumugam ◽  
Leidong Mao ◽  
Vladimir V. Popik ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Density ◽  
Surface Immobilization ◽  
Orthogonal Surface
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