scholarly journals Mixed Stimuli-Responsive Magnetic and Gold Nanoparticle System for Rapid Purification, Enrichment, and Detection of Biomarkers

2010 ◽  
Vol 21 (12) ◽  
pp. 2197-2204 ◽  
Author(s):  
Michael A. Nash ◽  
Paul Yager ◽  
Allan S. Hoffman ◽  
Patrick S. Stayton
Author(s):  
Bin Zhou ◽  
Lin-Fei Shi ◽  
Yong-Sheng Wang ◽  
Hui-Xian Yang ◽  
Jin-Hua Xue ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (24) ◽  
pp. 8087-8096
Author(s):  
Linying Li ◽  
C. Wyatt Shields ◽  
Jin Huang ◽  
Yiqun Zhang ◽  
Korine A. Ohiri ◽  
...  

Detection of biomarkers often requires extensive sample preparation. We report a simple acoustofluidic method to isolate biomarkers on elastomeric particles by co-aggregation of elastin-like polypeptides, enabling their efficient capture and release.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Young Min Bae ◽  
Seung Oh Jin ◽  
Insoo Kim ◽  
Ki Young Shin ◽  
Duchang Heo ◽  
...  

In the biosensing platform, label-free detection technique provides advantages such as the short analysis time and the cost-effectiveness. In this study, we showed the feasibility of the LSPR substrate with gold nanoparticle array for detecting low density lipoprotein (LDL) and high density lipoprotein (HDL) without labeling. The LSPR substrate was fabricated through the lift-off process with the anodized alumina mask, and its LSPR phenomenon was observed by measuring the optical transmission of substrate. The antibodies were immobilized on the gold nanoparticle array via the chemical binding, in which the 11-MUA was used as the linker to bind the antibodies. The binding of antibodies was confirmed by observing the shift of LSPR peak of the substrate. Finally, with the LSPR substrates with the antibodies immobilized, the detection of LDL and HDL was investigated. As a result, LDL and HDL could be detected in the clinically available concentration range, respectively.


2019 ◽  
Vol 2 (7) ◽  
pp. 2833-2839 ◽  
Author(s):  
Xiangdong Wang ◽  
Nuo Jin ◽  
Qiao Wang ◽  
Tao Liu ◽  
Kangcan Liu ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (81) ◽  
pp. 65651-65659 ◽  
Author(s):  
Kate Y. J. Lee ◽  
Yiqing Wang ◽  
Shuming Nie

A pH-sensitive multifunctional doxorubicin–gold nanoparticle drug delivery system, which has the potential to detect and treat tumors, was developed.


1999 ◽  
Vol 68 (12) ◽  
pp. 3810-3812 ◽  
Author(s):  
Hideyuki Inouye ◽  
Koichiro Tanaka ◽  
Ichiro Tanahashi ◽  
Yuki Kondo ◽  
Kazuyuki Hirao

2005 ◽  
Vol 31 (4) ◽  
pp. 277-282 ◽  
Author(s):  
Shen-ching-chi Juan ◽  
Chih-yu Hua ◽  
Cheng-lung Chen ◽  
Xiaoqiang Sun ◽  
Haitao Xi

2014 ◽  
Vol 2 (34) ◽  
pp. 5576-5584 ◽  
Author(s):  
Sreedevi Krishnakumar ◽  
Karical R. Gopidas

Novel Fréchet-type dendron based organic nanodots exhibiting stimuli responsive reversible morphological transformation have been synthesized by a one-pot reaction which involves etching off gold core of a gold nanoparticle cored dendrimer. Self-assembled FDNs can be utilized for encapsulation and on-demand release of guests.


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