Autonomous Self-Healing Silk Fibroin Injectable Hydrogels Formed via Surfactant-Free Hydrophobic Association

2019 ◽  
Vol 12 (1) ◽  
pp. 1628-1639 ◽  
Author(s):  
Lei Meng ◽  
Changyou Shao ◽  
Chen Cui ◽  
Feng Xu ◽  
Jiandu Lei ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Hydrophobic Association ◽  
Self Healing ◽  
Injectable Hydrogels

Effects of surfactant and ionic concentration on properties of dual physical crosslinking self-healing hydrogels by hydrophobic association and ionic interactions

2020 ◽  
Vol 44 (10) ◽  
pp. 4061-4070 ◽  
Author(s):  
Yayu Li ◽  
Tianyang Zhou ◽  
Zhangyong Yu ◽  
Fei Wang ◽  
Dongjian Shi ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Ionic Concentration ◽  
Hydrophobic Association ◽  
Ionic Interactions ◽  
Self Healing ◽  
Physical Crosslinking

Two kinds of dual crosslinking hydrogels have adjustable mechanical properties, self-healing and self-recovery performances.

Self-Healing and Injectable Hydrogels for Anticancer Drug Delivery: A Study with Multialdehyde Gum Arabic and Succinic Anhydride Chitosan

2020 ◽  
Vol 3 (12) ◽  
pp. 8460-8470
Author(s):  
Ashiq Hussain Pandit ◽  
Nasreen Mazumdar ◽  
Khalid Imtiyaz ◽  
M. Moshahid Alam Rizvi ◽  
Sharif Ahmad
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Succinic Anhydride ◽  
Gum Arabic ◽  
Self Healing ◽  
Injectable Hydrogels ◽  
Anticancer Drug Delivery

Highly stretchable, self-healing, and 3D printing prefabricatable hydrophobic association hydrogels with the assistance of electrostatic interaction

2020 ◽  
Vol 11 (29) ◽  
pp. 4741-4748
Author(s):  
Heng Chen ◽  
Beibei Hao ◽  
Penghui Ge ◽  
Shaojun Chen
Keyword(s):  
3D Printing ◽  
Electrostatic Interaction ◽  
Methacrylic Acid ◽  
Butyl Acrylate ◽  
Hydrophobic Association ◽  
Self Healing ◽  
Ethyl Methacrylate ◽  
Highly Stretchable ◽  
Physically Crosslinked

Self-healing and 3D printing prefabricatable physically crosslinked hydrogels were prepared by copolymerization of butyl acrylate, 2-(dimethylamino)ethyl methacrylate, and methacrylic acid, followed by soaking in water.

Design of Self-Healing and Electrically Conductive Silk Fibroin-Based Hydrogels

2019 ◽  
Vol 11 (22) ◽  
pp. 20394-20403 ◽  
Author(s):  
Lichao Liu ◽  
Yueying Han ◽  
Shanshan Lv
Keyword(s):  
Silk Fibroin ◽  
Self Healing ◽  
Electrically Conductive

A novel highly stretchable, adhesive and self-healing silk fibroin powder-based hydrogel containing dual-network structure

2019 ◽  
Vol 252 ◽  
pp. 126-129 ◽  
Author(s):  
Cai Wang ◽  
Yili Du ◽  
Biyan Chen ◽  
Shaojun Chen ◽  
Yiping Wang
Keyword(s):  
Silk Fibroin ◽  
Network Structure ◽  
Self Healing ◽  
Highly Stretchable

An autonomous self-healing hydrogel based on surfactant-free hydrophobic association

2017 ◽  
Vol 134 (19) ◽  
Author(s):  
Silas Owusu-Nkwantabisah ◽  
Jeffrey R. Gillmor ◽  
Steven C. Switalski ◽  
Gary L. Slater
Keyword(s):  
Hydrophobic Association ◽  
Self Healing

scholarly journals A Biocompatible, Stimuli-Responsive, and Injectable Hydrogel with Triple Dynamic Bonds

Molecules ◽  
2020 ◽  
Vol 25 (13) ◽  
pp. 3050
Author(s):  
Yujie Chen ◽  
Runjing Zhang ◽  
Baiqin Zheng ◽  
Chao Cai ◽  
Zhen Chen ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Clinical Applications ◽  
Carboxymethyl Chitosan ◽  
Self Healing ◽  
Stimuli Responsive ◽  
Covalent Bonds ◽  
Injectable Hydrogels ◽  
Handling Performance ◽  
Natural Polysaccharide

Injectable hydrogels have attracted growing interests as promising biomaterials for clinical applications, due to their minimum invasive implanting approach and easy-handling performance. Nevertheless, natural biomaterials-based injectable hydrogels with desirable nontoxicity are suffering from limited functions, failing to fulfill the requirements of clinical biomaterials. The development of novel injectable biomaterials with a combination of biocompatibility and adequate functional properties is a growing urgency toward biomedical applications. In this contribution, we report a simple and effective approach to fabricate multi-functional CMC-OSA-DTP hydrogels. Two kinds of natural polysaccharide derived polymers, carboxymethyl chitosan (CMC) and oxidized alginate (OSA) along with 3,3′-dithiopropionic acid dihydrazide (DTP) were utilized to introduce three dynamic covalent bonds. Owing to the existence of triple dynamic bonds, this unique CMC-OSA-DTP hydrogel possessed smart redox and pH stimuli-responsive property, injectability as well as self-healing ability. In addition, the CCK-8 and live/dead assays demonstrated satisfying cytocompatibility of the CMC-OSA-DTP hydrogel in vitro. Based on its attractive properties, this easy-fabricated and multi-functional hydrogel demonstrated the great potential as an injectable biomaterial in a variety of biomedical applications.

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