Smart NIR-Light-Mediated Nanotherapeutic Agents for Enhancing Tumor Accumulation and Overcoming Hypoxia in Synergistic Cancer Therapy

2019 ◽  
Vol 2 (3) ◽  
pp. 1225-1232 ◽  
Author(s):  
Xiangmei Liu ◽  
Kang Tian ◽  
Jinghui Zhang ◽  
Menglong Zhao ◽  
Shujuan Liu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Nir Light ◽  
Tumor Accumulation

Hypocrellin Derivative‐Loaded Calcium Phosphate Nanorods as NIR Light‐Triggered Phototheranostic Agents with Enhanced Tumor Accumulation for Cancer Therapy

ChemMedChem ◽  
2019 ◽  
Vol 15 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Hongyi Wang ◽  
Qingyan Jia ◽  
Weimin Liu ◽  
Fuchun Nan ◽  
Xiuli Zheng ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Cancer Therapy ◽  
Nir Light ◽  
Tumor Accumulation

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

Biodegradable Nano-photosensitizer with Photoactivatable Singlet Oxygen Generation for Synergistic Phototherapy

2021 ◽  
Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Promising Method ◽  
Normal Cells ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...

Engineered NIR light-responsive bacteria as anti-tumor agent for targeted and precise cancer therapy

2021 ◽  
pp. 130842
Author(s):  
Huizhuo Pan ◽  
Lianyue Li ◽  
Gaoju Pang ◽  
Chunli Han ◽  
Baona Liu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Nir Light ◽  
Tumor Agent

scholarly journals Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Deep Penetration ◽  
Nir Light

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

scholarly journals Fullerene/photosensitizer nanovesicles as highly efficient and clearable phototheranostics with enhanced tumor accumulation for cancer therapy

Biomaterials ◽  
2016 ◽  
Vol 103 ◽  
pp. 75-85 ◽  
Author(s):  
Mirong Guan ◽  
Jiechao Ge ◽  
Jingyi Wu ◽  
Guoqiang Zhang ◽  
Daiqin Chen ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Highly Efficient ◽  
Tumor Accumulation

CuFeSe2-based thermo-responsive multifunctional nanomaterial initiated by a single NIR light for hypoxic cancer therapy

2021 ◽  
Author(s):  
Juan Lu ◽  
Jun Yang ◽  
Dan Yang ◽  
Shanshan Hu ◽  
Qianqian Sun ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mr Imaging ◽  
Nir Light

A thermo-responsive CuFeSe2-based multifunctional nanomaterial was used for NIR light initiated hypoxic cancer therapy and CT/MR imaging.

A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

2020 ◽  
Vol 8 (12) ◽  
pp. 3418-3429 ◽  
Author(s):  
Yongju He ◽  
Linjie Shao ◽  
Ibrahim Usman ◽  
Yao Hu ◽  
Anqiang Pan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Ph Responsive ◽  
Epr Effect ◽  
Large Size ◽  
Rapid Clearance ◽  
Tumor Accumulation ◽  
Dual Drug

A pH-responsive dissociable mesoporous silica-based cluster with efficient dual-drug co-delivery for combinational cancer therapy, tumor accumulation via its large size-favored EPR effect and rapid clearance by its acid-triggered dissociation.

NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy

2018 ◽  
Vol 6 (47) ◽  
pp. 7794-7799 ◽  
Author(s):  
Rongrong Nie ◽  
Hongji Liu ◽  
Lin Hu ◽  
Xinyu Gu ◽  
Junchao Qian ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nir Light ◽  
Carbon Based

This communication reports a chitosan-gated carbon-based nanocarrier as a NIR light-switchable drug delivery system for controlled on/off drug release.

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