CuFeSe2-based thermo-responsive multifunctional nanomaterial initiated by a single NIR light for hypoxic cancer therapy

Author(s):  
Juan Lu ◽  
Jun Yang ◽  
Dan Yang ◽  
Shanshan Hu ◽  
Qianqian Sun ◽  
...  
Keyword(s):  

A thermo-responsive CuFeSe2-based multifunctional nanomaterial was used for NIR light initiated hypoxic cancer therapy and CT/MR imaging.

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...


Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...


2021 ◽  
pp. 130842
Author(s):  
Huizhuo Pan ◽  
Lianyue Li ◽  
Gaoju Pang ◽  
Chunli Han ◽  
Baona Liu ◽  
...  
Keyword(s):  

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.


ChemMedChem ◽  
2019 ◽  
Vol 15 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Hongyi Wang ◽  
Qingyan Jia ◽  
Weimin Liu ◽  
Fuchun Nan ◽  
Xiuli Zheng ◽  
...  

2018 ◽  
Vol 6 (47) ◽  
pp. 7794-7799 ◽  
Author(s):  
Rongrong Nie ◽  
Hongji Liu ◽  
Lin Hu ◽  
Xinyu Gu ◽  
Junchao Qian ◽  
...  

This communication reports a chitosan-gated carbon-based nanocarrier as a NIR light-switchable drug delivery system for controlled on/off drug release.


2015 ◽  
Vol 25 (25) ◽  
pp. 3966-3976 ◽  
Author(s):  
Fei He ◽  
Guixin Yang ◽  
Piaoping Yang ◽  
Yuxiu Yu ◽  
Ruichan Lv ◽  
...  
Keyword(s):  

Biomaterials ◽  
2010 ◽  
Vol 31 (34) ◽  
pp. 9065-9073 ◽  
Author(s):  
Xiaoqiang Yang ◽  
Jamison J. Grailer ◽  
Ian J. Rowland ◽  
Alireza Javadi ◽  
Samuel A. Hurley ◽  
...  

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