Regulation of DNA Self-Assembly and DNA Hybridization by Chiral Molecules with Corresponding Biosensor Applications

2015 ◽  
Vol 87 (4) ◽  
pp. 2058-2062 ◽  
Author(s):  
Benmei Wei ◽  
Nannan Liu ◽  
Juntao Zhang ◽  
Xiaowen Ou ◽  
Ruixue Duan ◽  
...  
2018 ◽  
Vol 2 (10) ◽  
pp. 1884-1892 ◽  
Author(s):  
Guangxi Huang ◽  
Rongsen Wen ◽  
Zhiming Wang ◽  
Bing Shi Li ◽  
Ben Zhong Tang

Two novel chiral molecules 1 and 2 were designed and synthesized. 1 displayed evident CPL activity, whereas 2 served as a highly selective and sensitive “turn-off” fluorescent chemosensor for Cu2+.


Author(s):  
Michael J. Heller ◽  
Benjamin Sullivan ◽  
Dietrich Dehlinger ◽  
Paul Swanson ◽  
Dalibor Hodko

2005 ◽  
Author(s):  
Do-Kyun Kim ◽  
Young-Soo Kwon ◽  
Yuzuru Takamura ◽  
Eiichi Tamiya

2012 ◽  
Vol 523-524 ◽  
pp. 598-603 ◽  
Author(s):  
Masafumi Yasuda ◽  
Terutake Hayashi ◽  
Masaki Michihata ◽  
Yasuhiro Takaya

We proposed a novel technique for self-assembly of micro parts by using DNA hybridization. As the demand for MEMS is growing, research on the self-assembly of micro parts is required to achieve fabrication of functional devices consisted of diverse micro parts. Our method has a unique characteristic where the selective assembly can be performed. At the targeted substrate region functionalized by single-stranded DNA, only components functionalized by the complementary one are assembled successfully. This is due to the complementary properties of DNA, which consists of four different bases (adenine (A), cytosine (C), guanine (G), and thymine (T)). A of one strand always pairs with a T of another, and so does C with G. The characteristic enables batch fabrication of diverse micro parts by using several kinds of DNA properly. Therefore, our method can be applied to the fabrication of MEMS. In this paper, in order to verify the feasibility of the automatic positioning using DNA hybridization, we performed a fundamental experiment for addressing polystyrene microspheres (1, 2, 6μm diameter) on the DNA patterned glass substrate.


Author(s):  
Michael Heller ◽  
Benjamin Sullivan ◽  
Dietrich Dehlinger ◽  
Paul Swanson ◽  
Dalibor Hodko

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