On-Demand Patterning of Protein Matrixes Inside a Microfluidic Device

2006 ◽  
Vol 78 (15) ◽  
pp. 5469-5473 ◽  
Author(s):  
Hirokazu Kaji ◽  
Masahiko Hashimoto ◽  
Matsuhiko Nishizawa
Keyword(s):  
Microfluidic Device ◽  
On Demand

scholarly journals A hybrid microfluidic device for on-demand orientation and multidirectional imaging ofC. elegansorgans and neurons

2016 ◽  
Vol 10 (6) ◽  
pp. 064111 ◽  
Author(s):  
Ramtin Ardeshiri ◽  
Ben Mulcahy ◽  
Mei Zhen ◽  
Pouya Rezai
Keyword(s):  
Microfluidic Device ◽  
On Demand

scholarly journals Microfluidic on-demand droplet generation, storage, retrieval, and merging for single-cell pairing

Lab on a Chip ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 493-502 ◽  
Author(s):  
Hesam Babahosseini ◽  
Tom Misteli ◽  
Don L. DeVoe
Keyword(s):  
Single Cell ◽  
Aqueous Phase ◽  
Microfluidic Device ◽  
Droplet Generation ◽  
Microfluidic Platform ◽  
On Demand

A multifunctional microfluidic platform combining on-demand aqueous-phase droplet generation, multi-droplet storage, and controlled merging of droplets selected from a storage library in a single integrated microfluidic device is described.

scholarly journals Indirect fabrication of versatile 3D microfluidic device by a rotating plate combined 3D printing system

RSC Advances ◽  
2018 ◽  
Vol 8 (66) ◽  
pp. 37693-37699 ◽  
Author(s):  
Dong-Heon Ha ◽  
Dong-Hyeon Ko ◽  
Jin-oh Kim ◽  
Do Jin Im ◽  
Byoung Soo Kim ◽  
...  
Keyword(s):  
3D Printing ◽  
Microfluidic Device ◽  
Chemical Resistance ◽  
Microfluidic Devices ◽  
On Demand ◽  
System P ◽  
Printing System ◽  
Sacrificial Materials ◽  
Printing Techniques ◽  
Rotating Plate

Rapid on-demand sacrificial printing techniques using suitable combinations of resin and sacrificial materials would be desirable to fabricate versatile and functional microfluidic devices with complex designs and chemical resistance.

scholarly journals On demand nanoliter-scale microfluidic droplet generation, injection, and mixing using a passive microfluidic device

2015 ◽  
Vol 9 (1) ◽  
pp. 014119 ◽  
Author(s):  
Uwe Tangen ◽  
Abhishek Sharma ◽  
Patrick Wagler ◽  
John S. McCaskill
Keyword(s):  
Microfluidic Device ◽  
Droplet Generation ◽  
On Demand

scholarly journals Selective cell encapsulation, lysis, pico-injection and size-controlled droplet generation using traveling surface acoustic waves in a microfluidic device

Lab on a Chip ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 3914-3921
Author(s):  
Kirk Mutafopulos ◽  
Peter J. Lu ◽  
Ryan Garry ◽  
Pascal Spink ◽  
David A. Weitz
Keyword(s):  
Microfluidic Device ◽  
Acoustic Waves ◽  
Single Cells ◽  
Surface Acoustic Waves ◽  
Cell Encapsulation ◽  
Droplet Generation ◽  
New Materials ◽  
On Demand ◽  
Interdigital Transducer ◽  
Size Controlled

We generate traveling surface acoustic waves with an interdigital transducer to create droplets on-demand; encapsulate single cells; lyse cells and immediately encapsulate their contents; and pico-inject new materials into existing droplets.

Pneumatic handling of droplets on-demand on a microfluidic device for seamless processing of reaction and electrophoretic separation

2010 ◽  
Vol 31 (22) ◽  
pp. 3719-3726 ◽  
Author(s):  
Shohei Kaneda ◽  
Koichi Ono ◽  
Tatsuhiro Fukuba ◽  
Takahiko Nojima ◽  
Takatoki Yamamoto ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Electrophoretic Separation ◽  
On Demand

scholarly journals On-demand radiosynthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) on an electrowetting-on-dielectric microfluidic chip for 18F-labeling of protein

RSC Advances ◽  
2019 ◽  
Vol 9 (55) ◽  
pp. 32175-32183 ◽  
Author(s):  
Hee-Kwon Kim ◽  
Muhammad Rashed Javed ◽  
Supin Chen ◽  
Kirstin A. Zettlitz ◽  
Jeffrey Collins ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Microfluidic Chip ◽  
Prosthetic Group ◽  
Electrowetting On Dielectric ◽  
On Demand

An all-electronic, droplet-based batch microfluidic device, operated using the electrowetting on dielectric (EWOD) mechanism was developed for on-demand synthesis of acommonly used 18F-prosthetic group for biomolecule labeling.

scholarly journals Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Xiang Wang ◽  
Shunbo Li ◽  
Limu Wang ◽  
Xin Yi ◽  
Yu Sanna Hui ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Iron Nanoparticles ◽  
High Accuracy ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
On Demand ◽  
Chemical Release ◽  
Magnetic Stimulus ◽  
Active Chemical ◽  
Sigmoidal Model

We report a robust magnetic-membrane-based microfluidic platform for controllable chemical release. The magnetic membrane was prepared by mixing polydimethylsiloxane (PDMS) and carbonyl-iron nanoparticles together to obtain a flexible thin film. With combined, simultaneous regulation of magnetic stimulus and mechanical pumping, the desired chemical release rate can easily be realized. For example, the dose release experimental data was well fitted by a mathematical sigmoidal model, exhibiting a typical dose-response relationship, which shows promise in providing significant guidance for on-demand drug delivery. To test the platform’s feasibility, our microfluidic device was employed in an experiment involvingEscherichia coliculture under controlled antibiotic ciprofloxacin exposure, and the expected outcomes were successfully obtained. Our experimental results indicate that such a microfluidic device, with high accuracy and easy manipulation properties, can legitimately be characterized as active chemical release system.

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