scholarly journals Selective cell encapsulation, lysis, pico-injection and size-controlled droplet generation using traveling surface acoustic waves in a microfluidic device

Lab on a Chip ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 3914-3921
Author(s):  
Kirk Mutafopulos ◽  
Peter J. Lu ◽  
Ryan Garry ◽  
Pascal Spink ◽  
David A. Weitz

We generate traveling surface acoustic waves with an interdigital transducer to create droplets on-demand; encapsulate single cells; lyse cells and immediately encapsulate their contents; and pico-inject new materials into existing droplets.

2013 ◽  
Vol 15 (3) ◽  
pp. 553-560 ◽  
Author(s):  
Liang Wu ◽  
Pu Chen ◽  
Yingsong Dong ◽  
Xiaojun Feng ◽  
Bi-Feng Liu

Lab on a Chip ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 493-502 ◽  
Author(s):  
Hesam Babahosseini ◽  
Tom Misteli ◽  
Don L. DeVoe

A multifunctional microfluidic platform combining on-demand aqueous-phase droplet generation, multi-droplet storage, and controlled merging of droplets selected from a storage library in a single integrated microfluidic device is described.


Lab on a Chip ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 4064-4070 ◽  
Author(s):  
Haiwei Lu ◽  
Kirk Mutafopulos ◽  
John A. Heyman ◽  
Pascal Spink ◽  
Liang Shen ◽  
...  

We introduce a microfluidic device that uses traveling surface acoustic waves to lyse bacteria with high efficiency. This lysis method should be applicable to a wide range of bacteria species and can be modified to analyze individual bacteria cells.


2015 ◽  
Vol 9 (1) ◽  
pp. 014119 ◽  
Author(s):  
Uwe Tangen ◽  
Abhishek Sharma ◽  
Patrick Wagler ◽  
John S. McCaskill

2008 ◽  
Vol 92 (9) ◽  
pp. 094104 ◽  
Author(s):  
Vincent Laude ◽  
Davy Gérard ◽  
Naima Khelfaoui ◽  
Carlos F. Jerez-Hanckes ◽  
Sarah Benchabane ◽  
...  

Lab on a Chip ◽  
2014 ◽  
Vol 14 (17) ◽  
pp. 3325-3333 ◽  
Author(s):  
Muhsincan Sesen ◽  
Tuncay Alan ◽  
Adrian Neild

Digital microfluidic chip merges multiple consecutive droplets (nl) selectively and controllably using surface acoustic waves.


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