Tuning biological properties of poly (vinyl alcohol) with amino acids and studying its influence on osteoblastic cell adhesion

2018 ◽  
Vol 86 ◽  
pp. 70-82 ◽  
Author(s):  
S. Mohanapriya ◽  
V. Raj
Keyword(s):  
Amino Acids ◽  
Cell Adhesion ◽  
Vinyl Alcohol ◽  
Biological Properties ◽  
Poly Vinyl Alcohol ◽  
Osteoblastic Cell

scholarly journals Effects of cryo-processing on the mechanical and biological properties of poly(vinyl alcohol)-gelatin theta-gels

2020 ◽  
Vol 15 (5) ◽  
pp. 051004 ◽  
Author(s):  
Patrick N. Charron ◽  
Jaime I. Jacobs ◽  
Selina X. Yao ◽  
Rachael A. Oldinski
Keyword(s):  
Vinyl Alcohol ◽  
Biological Properties ◽  
Poly Vinyl Alcohol

scholarly journals The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

RSC Advances ◽  
2019 ◽  
Vol 9 (22) ◽  
pp. 12346-12353 ◽  
Author(s):  
Petra Rejmontová ◽  
Adriana Kovalcik ◽  
Petr Humpolíček ◽  
Zdenka Capáková ◽  
Erik Wrzecionko ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Vinyl Alcohol ◽  
Biological Properties ◽  
Kraft Lignin ◽  
Poly Vinyl Alcohol

The mechanical properties of poly(vinyl alcohol) (PVA)-based scaffolds were successfully improved.

scholarly journals Preparation of Charged Poly(vinyl alcohol) Gel Membranes with Controlled Lattice Sizes and Permeability of Amino Acids.

1994 ◽  
Vol 51 (2) ◽  
pp. 87-92 ◽  
Author(s):  
Masamitsu MIYA ◽  
Toshiharu HAMADA ◽  
Tomoo SHIOMI ◽  
Kiyokazu IMAI
Keyword(s):  
Amino Acids ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Gel Membranes

Superior physicochemical and biological properties of poly(vinyl alcohol)/sericin hydrogels fabricated by a non-toxic gamma-irradiation technique

2016 ◽  
Vol 32 (1) ◽  
pp. 32-44 ◽  
Author(s):  
Rungnapa Yamdej ◽  
Karnwalee Pangza ◽  
Teerapol Srichana ◽  
Pornanong Aramwit
Keyword(s):  
Gamma Irradiation ◽  
Vinyl Alcohol ◽  
Tensile Modulus ◽  
Biological Properties ◽  
Poly Vinyl Alcohol ◽  
High Elongation ◽  
Physicochemical And Biological Properties ◽  
Migration Assays ◽  
Gamma Irradiated ◽  
High Degree

Gamma irradiation was used to fabricate crosslinked poly(vinyl alcohol)/sericin hydrogels with different sericin concentrations, and the physicochemical and biological properties of the gamma-irradiated poly(vinyl alcohol)/sericin hydrogels were characterized. Following gamma irradiation, the hydrogels had a high gel fraction (80%–95%), implying a high degree of crosslinking. Fourier transform infrared spectra confirmed the crosslinking bonds within the hydrogels, as seen by the characteristic shift in the peak. Furthermore, a low tensile modulus together with a high elongation percentage indicated that the hydrogels were easy to handle. We also showed that all hydrogels released sericin simultaneously. The poly(vinyl alcohol)/sericin hydrogels with high sericin content released more sericin, possibly due to less crosslinking of the hydrogels. When L929 cells were cultured with the hydrogel extracts, the cells were viable and could proliferate, particularly for the cells cultured with the hydrogels containing a high sericin content, which released more sericin. Migration assays also demonstrated that the cells migrated toward the medium extract of hydrogels containing high sericin. We suggest that sterile gamma-irradiated poly(vinyl alcohol)/sericin hydrogels could be used as a wound dressing for the treatment of dry and low-exudate wounds.

scholarly journals Plasma functionalization of poly(vinyl alcohol) hydrogel for cell adhesion enhancement

Biomatter ◽  
2013 ◽  
Vol 3 (4) ◽  
pp. e25414 ◽  
Author(s):  
Julia M. Ino ◽  
Pascale Chevallier ◽  
Didier Letourneur ◽  
Diego Mantovani ◽  
Catherine Le Visage
Keyword(s):  
Cell Adhesion ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Plasma Functionalization

Furanone-containing poly(vinyl alcohol) nanofibers for cell-adhesion inhibition

2013 ◽  
Vol 47 (3) ◽  
pp. 1049-1059 ◽  
Author(s):  
Nonjabulo P. Gule ◽  
Michele de Kwaadsteniet ◽  
Thomas E. Cloete ◽  
Bert Klumperman
Keyword(s):  
Cell Adhesion ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Adhesion Inhibition

Hydroxyapatite-Poly(Vinyl Alcohol)-Sodium Alginate Porous Hydrogels with Poly(Vinyl Alcohol) Surface Layer Used for Articular Cartilage Repair

2016 ◽  
Vol 852 ◽  
pp. 1155-1161 ◽  
Author(s):  
Xiao Bing Luo ◽  
Ming Feng Ma ◽  
Xian Ju Zhou
Keyword(s):  
Articular Cartilage ◽  
Sodium Alginate ◽  
Vinyl Alcohol ◽  
Biological Properties ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
X Ray ◽  
Composite Hydrogels ◽  
Good Potential ◽  
Gas Foaming

The double-layered PVA/nanohydroxyapatite (nHA)-poly (vinyl alcohol)(PVA)-sodium alginate (SA) porous composite scaffolds used as synthetic articular cartilage were prepared by the freeze-thawing method, gas foaming method and crosslink method of Ca2+ ion, i.e., upper PVA layer for the cartilage substitute and underlying SA30 porous hydrogels for bone bonding. The microstructure and morphology of composite hydrogels were characterized using scanning electronic microscopy (SEM).It had high porosity and uniform pores. The content of HA in SA30 matrix were tested by Energy-dispersive X-ray spectroscopy (EDS). The biological properties of the composite hydrogels had been evaluated by co-culture and MTT. All results indicate that the PVA/SA30 hydrogels has good potential for repairing or replacing articular cartilage.

Physically crosslinked poly(vinyl alcohol)–carrageenan composite hydrogels: pore structure stability and cell adhesive ability

RSC Advances ◽  
2015 ◽  
Vol 5 (95) ◽  
pp. 78180-78191 ◽  
Author(s):  
Yabin Zhang ◽  
Lei Ye ◽  
Man Cui ◽  
Boguang Yang ◽  
Junjie Li ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Structure Stability ◽  
Pore Collapse ◽  
Composite Hydrogels ◽  
Cell Adhesive ◽  
Adhesive Ability ◽  
Physically Crosslinked ◽  
Enhance Cell Adhesion

Poly(vinyl alcohol) (PVA)–carrageenan (CAR) composite hydrogels can reduce pore collapse during lyophilization and enhance cell adhesion in comparison to pure PVA hydrogels.

Fabrication of curcumin-loaded gum tragacanth/poly(vinyl alcohol) nanofibers with optimized electrospinning parameters

2016 ◽  
Vol 46 (5) ◽  
pp. 1170-1192 ◽  
Author(s):  
Marziyeh Ranjbar-Mohammadi ◽  
Saeid Kargozar ◽  
S Hajir Bahrami ◽  
MT Joghataei
Keyword(s):  
Response Surface ◽  
Vinyl Alcohol ◽  
Polymer Concentration ◽  
Back Propagation ◽  
Average Diameter ◽  
Biological Properties ◽  
Poly Vinyl Alcohol ◽  
Surface Model ◽  
Back Propagation Algorithm ◽  
Gum Tragacanth

This paper focuses on using response surface methodology (RSM) and artificial neural network (ANN) to optimize the diameter of Gum tragacanth (GT)/poly(vinyl alcohol) (PVA) nanofibers. However, producing curcumin-loaded GT/PVA nanofibers with using these optimized conditions is another aim. RSM methodology based on four variables (voltage, feed rate, distance between nozzle and collector, and solution concentration) with three levels and ANN technique were compared for modeling the average diameter of nanofibers. In the RSM method, the individual and interaction effects between the parameters on the average diameter of nanofibers were determined using Box-Behnken design (BBD). Data sets of input–output patterns were used for training the multilayer perceptron (MP) neural networks trained with back-propagation algorithm for modeling purpose. Experimental results for both ANN and RSM techniques showed agreement with the predicted fiber diameter. High-regression coefficient between the variables and the response displayed that the performance of RSM for minimizing diameter of nanofibers was better than ANN. Based on response surface model, optimum conditions (polymer concentration of 4.2% (w/v), distance between the capillary and collector 20 cm, applied voltage of 20 kV and flow rate of 0.5 mL/h) were obtained for producing GT/PVA nanofibers with minimized diameter. Then curcumin-loaded GT/PVA nanofibers were produced with acquired optimum condition and the effect of curcumin concentration (3 and 5% (w/v)) on the morphology, diameter and biological properties of nanofibers was investigated.

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