Control of diabetic patients: Comparison of information obtained from fasting blood sugar level and the glycemic cycle

1974 ◽  
Vol 11 (4) ◽  
pp. 340-346
Author(s):  
Luc Méjean ◽  
Pierre Drouin ◽  
Jean-Marie Martin ◽  
Gerard Debry
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tafere Tilahun Aniley ◽  
Legesse Kassa Debusho ◽  
Zelalem Mehari Nigusie ◽  
Wondwosen Kassahun Yimer ◽  
Belay Birlie Yimer

Author(s):  
Fatemeh Owlia ◽  
Abbas-Ali Jafari ◽  
Saeed Hossein Khalilzadeh ◽  
Fatemeh Hajimir

Introduction: Diabetes is the most common metabolic disease, which can cause different effects on oral mucosa. Oral candidiasis is one of the most common lesions, particularly in un-controlled diabetic patients. The purpose of this study was evaluation of relationship between Candida colony counts of whole saliva and fasting blood sugar level and determination of candida species in un-controlled and controlled diabetic patients. Methods: This analytical case-control study was conducted on ninety diabetic patients, consisted of 45 patients with uncontrolled diabetes (HBA1C>7) and 45 patients with controlled diabetes (HBA1C<7). Demographic data and history of systemic disease were evaluated. The whole saliva samples were collected by spitting method and cultured on Sabouraud dextrose agar (SDA) and chromogenic agar for determining oral candida spices and colonization. Data were analyzed using SPSS17 and statistical T-test, chi-square and Pearson correlation tests. Results: Data analysis showed statistically significant higher positive candidal growth in uncontrolled group when compared to controlled group. C. albicans was the most common isolated Candida species in both groups. Significant positive correlation of CFU/ml with fasting blood sugar level in both groups was not seen. Conclusion: In spite of higher rate of candida colonization in uncontrolled diabetic patients, there is no significant relation with fasting blood sugar level.


2021 ◽  
Author(s):  
Sewnet Adem Kebede ◽  
Zemenu Tadesse Tessema ◽  
Shitaye Alemu Balcha ◽  
Tadesse Awoke Ayele

Abstract Background: Early identification of prognostic factors and close monitoring of the biomarkers is used to monitor the occurrence or progression of diabetic retinopathy. Therefore, this study aimed to assess change in fasting blood sugar level, time to diabetic retinopathy and its predictors among type 2 diabetes patients in Ethiopia.Methods: Institution based retrospective follow-up study was conducted at University of Gondar Comprehensive Specialized Hospital. Linear mixed effect model and cox proportional hazard models were fitted separately and later the two models were fitted jointly using R software. Variables with p-value <0.05 were considered as significant predictors in the adjusted analysis.Result: The incidence rate of diabetic retinopathy was 2 per 100-person year of observation with median follow up time of 90.8 months (IQR: 63.4). The current value and rate of change in fasting blood sugar level were significant predictors of time to diabetic retinopathy (AHR=1.35;95% CI: 1.12-1.63) and (AHR=1.70; 95%CI:1.21-2.39) respectively. Hypertension (AHR=2.49; 95%CI: 1.32-4.66), taking >1 antidiabetic oral agent (AHR=4.90; 95%CI: 1.07-20.0) and more than 10 years duration (AHR=0.17, 95% CI: 0.06-0.46) were predictors of time to diabetic retinopathy.Conclusion: This study revealed that medication, duration, weight, current age, and time have significant association with the progression change of fasting blood sugar. On the other hand, hypertension, medication and duration were significant predictors of time to diabetic retinopathy. The current value of fasting blood sugar and rate of fasting blood sugar change were significantly associated with time to diabetic retinopathy.


2021 ◽  
Vol 16 (8) ◽  
pp. 98-102
Author(s):  
Hashim Abdul Razzaq Iman ◽  
Hussein Murtadha Jinan

Diabetes mellitus type 2 (T2DM) results from beta cell dysfunction or reduced action of insulin responsive. The objective of this study was to examine the relevance between blood sugar, the activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in fasting women diabetic patients in different durations. A total of sixty-eight women were divided into three groups: first a healthy group – non-diabetic (twenty-six women), second and third groups (twenty-one) were diabetic patients of age 35 – 50 and 51 – 69 years respectively. Serum fasting blood sugar was significantly (P < 0.05) elevated to 181.60 mg/dl in female patients with 35 – 50 years. The same effect happened in activity of AST to 32.91 u/L in 51 – 69 years and ALT was 28.43 u/L in 35 – 50 years. No significant differences were found between the aged and fasting blood sugar, AST and ALT in diabetic patients. The correlation factor (r) between fasting blood sugar and the activity of ALT was highly significant.


Author(s):  
Soni .

Background: Diabetes increases the risk of macrovascular complications and is often associated with angina in patient. Currently nicorandil, a potassium channel opener is being frequently used for the prevention and long-term treatment of angina pectoris. Glibenclamide exerts its antidiabetic action by closing the ATP sensitive potassium channels. Simultaneous use of nicorandil may antagonizes this action and may worsens the existing diabetes. To evaluate the pharmacodynamic interaction present study has been taken to study the effect of Nicorandil, a potassium channel opener on blood glucose level of alloxan induced diabetic rats and its pharmacodynamics interaction with Glibenclamide.Methods: Albino rats, weighing 150-200gm of male sex were used for the study. Diabetes was induced by injecting alloxan monohydrate 2% solution intra peritoneally in a dose of 150mg/kg body weight. Animal with Fasting Blood Sugar level between 250-300g/dl was selected for study and they were divided into 4 groups of 5 animals each. Group I- serving as control received 0.5ml normal saline orally for 28 days. Group II was given glibenclamide (0.5mg/kg body wt) for 28 days. Group III was treated orally with nicorandil (0.3mg/kg body wt) for 28 days. Group IV was given glibenclamide (0.5mg/kg) and nicorandil (0.3mg/kg) for 28 days. Fasting Blood Sugar level was recorded in all rats on 1st,3rd,7th,14th,21st and 28th day of the treatments.Results: results showed that glibenclamide significantly reduce blood sugar level (p <0.05) Wherase nicorandil showed rise in blood glucose level (p <0.05) While the combination (glibenclamide + nicorandil) showed rise in blood glucose (p <0.05) overall.Conclusions: Nicorandil worsen the existing diabetes and to be avoided or replaced with alternative drug in case of diabetes being treated with sulfonyl urease group of drugs.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Reiner C. Polii ◽  
Billy J. Kepel ◽  
Widdhi Bodhi ◽  
Aaltje E. Manampiring

Abstract: Obesity has become a serious problem world-wide. Obesity occurs due to the imbalance of intake and output energy. Thus, it is related with the incidence of insulin resistance and the disruption of glucose metabolism. This study was aimed to obtain the correlation between fasting blood sugar level and obesity in adolescents. This was an analytical study with a cross-sectional design. The results showed that the major category of subjects was obese I (38.33%). The highest percentage was normal blood sugar which was found in non-obese adolescent (96.8%). The Spearman correlation test showed a sweak correlation between obesity and fasting blood sugar level in adolescent (r=0.386; p=0.004). Conclusion: There was a significant weak correlation between fasting blood sugar level and obesity in adolescents.Keywords: obesity, fasting blood glucose, adolescent. Abstrak: Obesitas menjadi masalah di seluruh dunia baik di negara maju maupun negara berkembang, prevalensinya pun meningkat begitu pesat. Obesitas terjadi karena adanya ketidakseimbangan antara energi yang masuk dengan energi yang keluar. Obesitas berkaitan dengan terjadinya resitensi insulin dan gangguan metabolisme glukosa.Penelitian ini bertujuan untuk mengetahui hubungan kadar glukosa darah puasa dengan obesitas pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara. Jenis penelitian ialah analitik dengan desain potong lintang. Hasil penelitian menunjukkan bahwa subjek penelitian terbanyak dalam kategori obes I (25,0-29,9 kg/m2) sebesar 38,33%. Kadar gula darah normal pada remaja non-obes dengan persentasi tertinggi (96,8%). Analisis korelasi Spearman pada kedua variabel memperoleh nilai koefisien korelasi r = 0,368 (p = 0,004). Simpulan: Terdapat hubungan bermakna yang lemah antara kadar gula darah puasa dan obesitas pada remaja. Kata kunci: obesitas, gula darah puasa, remaja


2010 ◽  
Vol 7 (4) ◽  
pp. 1410-1415
Author(s):  
Baghdad Science Journal

This study was done at Al-Balad City Hospital on 60 diabetic patients (25 male and 35 female). The study included Fasting Blood Sugar and fungal diagnosis (systemic and superficial fungus). The results showed that the high concentration of blood sugar belonged to the group > 70 years among the diabetic patients with high significant differences in comparison with other groups P


1958 ◽  
Vol 192 (3) ◽  
pp. 482-484 ◽  
Author(s):  
L. L. Langley ◽  
C. H. Gunthorpe ◽  
W. A. Beall

There is no glucose in the parotid saliva of normal, untreated dogs. Glucose appears in the saliva when the blood sugar is elevated to about 512 mg%. If insulin is given along with the infusion of glucose, the threshold is elevated to approximately 1235 mg%. Conversely, in alloxan diabetic dogs there is glucose in the saliva at the fasting blood sugar level. In this series that level averaged 269 mg%. Apparently the passage of glucose from the blood to the saliva is more than a simple permeability function. Glandular intracellular carbohydrate metabolism may be involved.


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