Intercellular communication and tissue growth

1971 ◽  
Vol 6 (4) ◽  
pp. 368-385 ◽  
Author(s):  
R. Azarnia ◽  
W. R. Loewenstein
Keyword(s):  
Intercellular Communication ◽  
Tissue Growth

scholarly journals INTERCELLULAR COMMUNICATION AND TISSUE GROWTH

1967 ◽  
Vol 33 (2) ◽  
pp. 235-242 ◽  
Author(s):  
Werner R. Loewenstein ◽  
Richard D. Penn
Keyword(s):  
Intercellular Communication ◽  
Wound Closure ◽  
Cell Movement ◽  
Normal Growth ◽  
Tissue Growth ◽  
Cellular Communication ◽  
Mechanical Contact ◽  
Cell Systems ◽  
Intact State ◽  
Striking Contrast

Intercellular communication was examined in regenerating rat liver and urodele skin, two tissues of fast but normal growth. In both, cellular communication is in general as good as in their respective normal intact state. This stands in striking contrast to the lack of cellular communication in tissues with cancerous growth. Upon wounding of the urodele skin, the normally permeable junctional membranes of cells near the wound border seal themselves off, thereby insulating the interiors of the communicated cell systems from the exterior. When the cells of two opposing borders make mechanical contact in the course of wound closure, communication between them ensues within 30 min. Within this period all cell movement also ceases ("contact inhibition"). The possible implications of these findings in the control of tissue growth are discussed.

scholarly journals INTERCELLULAR COMMUNICATION AND TISSUE GROWTH

1968 ◽  
Vol 38 (3) ◽  
pp. 556-561 ◽  
Author(s):  
A. Jamakosmanović ◽  
W. R. Loewenstein
Keyword(s):  
Intercellular Communication ◽  
Tissue Growth ◽  
Membrane Potentials ◽  
Normal Cells ◽  
Thyroid Cancers ◽  
Normal Thyroid

Intercellular communication was examined in normal and cancerous isolated thyroids with an intracellular electrical technique. The cells of normal thyroid (rat, mouse, hamster, man) communicate, within any given follicle, through permeable junctions. The cells of a wide variety of thyroid cancers (rat, hamster) do not communicate to any detectable degree and have resting membrane potentials lower than those of normal cells.

Intercellular communication and tissue growth

1969 ◽  
Vol 1 (1) ◽  
pp. 274-293 ◽  
Author(s):  
Carmia Borek ◽  
S. Higashino ◽  
W. R. Loewenstein
Keyword(s):  
Intercellular Communication ◽  
Tissue Growth

Intercellular communication and tissue growth

1972 ◽  
Vol 10 (1) ◽  
pp. 247-258 ◽  
Author(s):  
R. Azarnia ◽  
W. Michalke ◽  
W. R. Loewenstein
Keyword(s):  
Intercellular Communication ◽  
Tissue Growth

scholarly journals INTERCELLULAR COMMUNICATION AND TISSUE GROWTH

1967 ◽  
Vol 33 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Werner R. Loewenstein ◽  
Yoshinobu Kanno
Keyword(s):  
Cancer Cells ◽  
Membrane Permeability ◽  
Intercellular Communication ◽  
Surface Membrane ◽  
Cell Cancer ◽  
Normal Liver ◽  
Liver Cells ◽  
Tissue Growth ◽  
Liver Cancers ◽  
Strong Barrier

Intercellular communication was examined with intracellular electrical techniques in primary and transplanted rat liver cancers. Normal liver cells communicate rather freely with each other through permeable junctional membranes. Cancer liver cells show no communication at all; their surface membrane is a strong barrier to diffusion all around the cell. Cancer cells induce alterations in membrane permeability in normal liver cells; communication among the latter is markedly reduced when cancer cells grow near them.

Rheometers, Bioreactors, and Vocalization Forces: Using Basic Science Investigations to Help the Voices of Teachers

2008 ◽  
Vol 18 (3) ◽  
pp. 119-125
Author(s):  
Sarah Klemuk
Keyword(s):  
Basic Science ◽  
Tissue Growth ◽  
University Of Iowa ◽  
Support Cell ◽  
Rest Periods ◽  
Collaborative Studies ◽  
Professional Voice Users ◽  
The University ◽  
Science Investigations ◽  
Professional Voice

Abstract Collaborative studies at the University of Iowa and the National Center for Voice and Speech aim to help the voices of teachers. Investigators study how cells and tissues respond to vibration doses simulating typical vocalization patterns of teachers. A commercially manufactured instrument is uniquely modified to support cell and tissue growth, to subject tissues to vocalization-like forces, and to measure viscoelastic properties of tissues. Through this basic science approach, steps toward safety limits for vocalization and habilitating rest periods for professional voice users will be achieved.

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