Establishment of contracting heart muscle cell cultures

1977 ◽  
Vol 3 (3) ◽  
pp. 637-640 ◽  
Author(s):  
A. P. Bollon ◽  
K. Nath ◽  
J. W. Shay
Keyword(s):  
Muscle Cell ◽  
Cell Cultures ◽  
Heart Muscle ◽  
Heart Muscle Cell ◽  
Contracting Heart

Functional alterations of cardiac subcellular structures during energy deficiency in relation to the metabolic state of the heart muscle cell

1980 ◽  
Vol 75 (1) ◽  
pp. 97-104 ◽  
Author(s):  
P. G. Spieckermann ◽  
M. M. Gebhard ◽  
G. G. Göring ◽  
H. Kahles ◽  
V. A. Mezger ◽  
...  
Keyword(s):  
Muscle Cell ◽  
Heart Muscle ◽  
Heart Muscle Cell ◽  
Metabolic State ◽  
Energy Deficiency

Activity of complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation

2004 ◽  
Vol 18 (11) ◽  
pp. 1300-1302 ◽  
Author(s):  
Dimitry Spitkovsky ◽  
Philipp Sasse ◽  
Eugen Kolossov ◽  
Cornelia Böttinger ◽  
Bernd K. Fleischmann ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Electron Transport ◽  
Muscle Cell ◽  
Heart Muscle ◽  
Electron Transport Chain ◽  
Complex Iii ◽  
Mitochondrial Electron Transport Chain ◽  
Heart Muscle Cell ◽  
Muscle Cell Differentiation ◽  
Transport Chain

scholarly journals Engineering the Microenvironment for Heart Muscle Cell Mechanobiology

2020 ◽  
Vol 118 (3) ◽  
pp. 154a
Author(s):  
Erica A. Castillo ◽  
Kerry Lane ◽  
Orlando Chirikian ◽  
Samuel Feinstein ◽  
Cheavar Blair ◽  
...  
Keyword(s):  
Muscle Cell ◽  
Heart Muscle ◽  
Heart Muscle Cell

scholarly journals Is the Fundamental Electrical Response of the Single Heart Muscle Cell a Spike Potential?

1963 ◽  
Vol 46 (5) ◽  
pp. 1029-1046 ◽  
Author(s):  
Leon Churney ◽  
Hisashi Ohshima
Keyword(s):  
Action Potential ◽  
Muscle Cell ◽  
Heart Muscle ◽  
Action Potentials ◽  
Electrical Response ◽  
Microelectrode Recording ◽  
Crucial Experiment ◽  
Heart Muscle Cell ◽  
Spike Potential ◽  
Intermediate Size

The urodele amphibians, Amphiuma and Necturus, provide heart fibers large enough to serve for microelectrode recording under visual control with the microscope. Bundles containing as few as 5 to 10 fibers yield spike potentials, rather than the plateau forms generally considered to be characteristic of heart muscle. These spikes fail to overshoot. The plateau form, and only the plateau form, is recorded exclusively from large tissue masses. An intermingling of spikes and plateau-shaped action potentials is obtained from bundles of intermediate size. These data are confirmed in experiments in which the myocardium is sliced into adhering strips of unequal sizes. The conclusion is drawn that the configuration of the recorded action potential curve is contingent upon the mass and geometry of the tissue impaled by the microelectrode. The crucial experiment of recording from an isolated single heart fiber is not possible, because of the attendant injury. Our proposal that the spike form is the elemental heart action potential is, to this extent, an extrapolation. Attempts to explain the nature of the spike along classical lines are not entirely satisfactory. Other theories are considered which, in their turn, are generally unacceptable. Evidently only further experimentation can clarify the situation.

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