Relations between the effect of tetanus toxin on the neuromuscular transmission and histological functional properties of various muscles of the rat

1980 ◽  
Vol 38 (2) ◽  
Author(s):  
H. Kretzschmar ◽  
F. Kirchner ◽  
K. Takano
Keyword(s):  
Functional Properties ◽  
Tetanus Toxin ◽  
Neuromuscular Transmission

Action of tetanus toxin on neuromuscular transmission

1964 ◽  
Vol 58 (4) ◽  
pp. 1199-1203
Author(s):  
G. N. Kryzhanovskii ◽  
A. Kh. Kasymov
Keyword(s):  
Tetanus Toxin ◽  
Neuromuscular Transmission

The Effect of Tetanus Toxin on Neuromuscular Transmission

1970 ◽  
Vol 3 (4) ◽  
pp. 193-205 ◽  
Author(s):  
H.E. Kaeser ◽  
A. Saner
Keyword(s):  
Tetanus Toxin ◽  
Neuromuscular Transmission

Fragment A-B of tetanus toxin does not block neuromuscular transmission in the goldfish

Toxicon ◽  
1990 ◽  
Vol 28 (6) ◽  
pp. 737-741 ◽  
Author(s):  
J. Mellanby ◽  
M. Matsuda ◽  
N. Sugimoto ◽  
D.-L. Lei ◽  
B. Bizzini
Keyword(s):  
Tetanus Toxin ◽  
Neuromuscular Transmission

Quaternary structure of Limulus polyphemus hemocyanin

1978 ◽  
Vol 36 (2) ◽  
pp. 176-177
Author(s):  
T. Wichertjes ◽  
E.J. Kwak ◽  
E.F.J. Van Bruggen
Keyword(s):  
Electron Microscopy ◽  
Functional Properties ◽  
Horseshoe Crab ◽  
Temperature Jump ◽  
Quaternary Structure ◽  
Crystallographic Analysis ◽  
Limulus Polyphemus ◽  
Oxygen Binding ◽  
X Ray ◽  
Intact Molecule

Hemocyanin of the horseshoe crab (Limulus polyphemus) has been studied in nany ways. Recently the structure, dissociation and reassembly was studied using electron microscopy of negatively stained specimens as the method of investigation. Crystallization of the protein proved to be possible and X-ray crystallographic analysis was started. Also fluorescence properties of the hemocyanin after dialysis against Tris-glycine buffer + 0.01 M EDTA pH 8.9 (so called “stripped” hemocyanin) and its fractions II and V were studied, as well as functional properties of the fractions by NMR. Finally the temperature-jump method was used for assaying the oxygen binding of the dissociating molecule and of preparations of isolated subunits. Nevertheless very little is known about the structure of the intact molecule. Schutter et al. suggested that the molecule possibly consists of two halves, combined in a staggered way, the halves themselves consisting of four subunits arranged in a square.

Two-Dimensional Crystallization of Tetanus Toxin

1985 ◽  
Vol 43 ◽  
pp. 528-529
Author(s):  
Jeffry A. Reidler ◽  
John P. Robinson
Keyword(s):  
Electron Microscopy ◽  
Tetanus Toxin ◽  
Structural Information ◽  
Three Dimensional ◽  
Two Dimensional ◽  
Membrane Interface ◽  
3D Reconstructions ◽  
Cellular Receptors ◽  
Computer Reconstruction ◽  
2D Crystals

We have prepared two-dimensional (2D) crystals of tetanus toxin using procedures developed by Uzgiris and Kornberg for the directed production of 2D crystals of monoclonal antibodies at an antigen-phospholipid monolayer interface. The tetanus toxin crystals were formed using a small mole fraction of the natural receptor, GT1, incorporated into phosphatidyl choline monolayers. The crystals formed at low concentration overnight. Two dimensional crystals of this type are particularly useful for structure determination using electron microscopy and computer image refinement. Three dimensional (3D) structural information can be derived from these crystals by computer reconstruction of photographs of toxin crystals taken at different tilt angles. Such 3D reconstructions may help elucidate the mechanism of entry of the enzymatic subunit of toxins into cells, particularly since these crystals form directly on a membrane interface at similar concentrations of ganglioside GT1 to the natural cellular receptors.

Effect of halothane on neuromuscular transmission

JAMA ◽  
1966 ◽  
Vol 197 (10) ◽  
pp. 770-774 ◽  
Author(s):  
A. J. Gissen
Keyword(s):  
Neuromuscular Transmission

Structural and functional properties of Escherichia coli-derived nucleoplasmin A comparative study of recombinant and natural proteins

2001 ◽  
Vol 268 (6) ◽  
pp. 1739-1748
Author(s):  
Aitor Hierro ◽  
Jesus M. Arizmendi ◽  
Javier De Las Rivas ◽  
M. Angeles Urbaneja ◽  
Adelina Prado ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Comparative Study ◽  
Functional Properties ◽  
Structural And Functional Properties
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