scholarly journals Tools 2021: New methods, new approaches, and a salute to recent developments in protein science

2020 ◽  
Vol 30 (1) ◽  
pp. 5-7
Author(s):  
Brian W. Matthews
2019 ◽  
Vol 26 (8) ◽  
pp. 1311-1327 ◽  
Author(s):  
Pala Rajasekharreddy ◽  
Chao Huang ◽  
Siddhardha Busi ◽  
Jobina Rajkumari ◽  
Ming-Hong Tai ◽  
...  

With the emergence of nanotechnology, new methods have been developed for engineering various nanoparticles for biomedical applications. Nanotheranostics is a burgeoning research field with tremendous prospects for the improvement of diagnosis and treatment of various cancers. However, the development of biocompatible and efficient drug/gene delivery theranostic systems still remains a challenge. Green synthetic approach of nanoparticles with low capital and operating expenses, reduced environmental pollution and better biocompatibility and stability is a latest and novel field, which is advantageous over chemical or physical nanoparticle synthesis methods. In this article, we summarize the recent research progresses related to green synthesized nanoparticles for cancer theranostic applications, and we also conclude with a look at the current challenges and insight into the future directions based on recent developments in these areas.


1990 ◽  
Vol 18 (1_part_1) ◽  
pp. 65-74
Author(s):  
John M. Frazier ◽  
Alan M. Goldberg

Biomedical endeavours can be divided into three major categories: research, education, and testing. Within the context of each of these categories, activities involving whole animals have made major contributions and will continue to do so in the future. However, with technological developments in the areas of biotechnology and computers, new methods are already reducing the use of whole animals in certain areas. This article discusses the general issues of alternatives and then focuses on the development of new approaches to toxicity testing.


2021 ◽  
Vol 22 (5) ◽  
pp. 2585
Author(s):  
Silvia Vasiliu ◽  
Stefania Racovita ◽  
Ionela Aurica Gugoasa ◽  
Maria-Andreea Lungan ◽  
Marcel Popa ◽  
...  

Dentistry, as a branch of medicine, has undergone continuous evolution over time. The scientific world has focused its attention on the development of new methods and materials with improved properties that meet the needs of patients. For this purpose, the replacement of so-called “passive” dental materials that do not interact with the oral environment with “smart/intelligent” materials that have the capability to change their shape, color, or size in response to an externally stimulus, such as the temperature, pH, light, moisture, stress, electric or magnetic fields, and chemical compounds, has received much attention in recent years. A strong trend in dental applications is to apply nanotechnology and smart nanomaterials such as nanoclays, nanofibers, nanocomposites, nanobubbles, nanocapsules, solid-lipid nanoparticles, nanospheres, metallic nanoparticles, nanotubes, and nanocrystals. Among the nanomaterials, the smart nanoparticles present several advantages compared to other materials, creating the possibility to use them in various dental applications, including preventive dentistry, endodontics, restoration, and periodontal diseases. This review is focused on the recent developments and dental applications (drug delivery systems and restoration materials) of smart nanoparticles.


Author(s):  
Douglass F. Taber ◽  
Tristan Lambert

Organic synthesis is a vibrant and rapidly evolving field; chemists can now cyclize alkenes directly onto enones. Like the first five books in this series, Organic Synthesis: State of the Art 2013-2015 will lead readers quickly to the most important recent developments in a research area. This series offers chemists a way to stay abreast of what's new and exciting in organic synthesis. The cumulative reaction/transformation index of 2013-2015 outlines all significant new organic transformations over the past twelve years. Future volumes will continue to come out every two years. The 2013-2015 volume features the best new methods in subspecialties such as C-O, C-N and C-C ring construction, catalytic asymmetric synthesis, selective C-H functionalization, and enantioselective epoxidation. This text consolidates two years of Douglass Taber's popular weekly online column, "Organic Chemistry Highlights" as featured on the organic-chemistry.org website and also features cumulative indices of all six volumes in this series, going back twelve years.


Upravlenie ◽  
10.12737/2819 ◽  
2014 ◽  
Vol 2 (1) ◽  
pp. 57-60
Author(s):  
Мальчевский ◽  
A. Malchevskiy ◽  
Афанасьев ◽  
Valentin Afanasev

Application of new methods for managing large-scale integrated structures are considered as exemplified by the bank holding company. The factors urging the use of new approaches are highlighted. The author gives solid ground for options and prospects for development of conceptual approach, ensuring consistency of goals and enhancing integration of a holding company’s components.


2001 ◽  
Vol os8 (2) ◽  
pp. 59-62 ◽  
Author(s):  
Jackie E Brown

The number of dental radiographs taken in the UK has steadily increased over the past 20 years—recently estimating around 18 million taken in the general dental services alone, and dental radiographs now account for nearly 25% of all medical radiographic exposures.1 Radiographs remain our most useful diagnostic aid. Their strength is in demonstrating hard tissue pathology, which makes radiographs particularly effective in the maxillofacial region. Although well accepted in this capacity, there remain a number of limitations and drawbacks to conventional radiographs which recent developments have begun to overcome. There have been improvements in the scope and capabilities of dental imaging equipment. There has also been a continuing effort to reduce radiation-induced harm by limiting our exposure to it. This has been possible both through the introduction of new methods and protocols for reducing individual radiation exposures and by the creation of guidelines for selecting radiographs more effectively and thereby reducing the total number of radiographs taken.


1999 ◽  
Vol 2 (3) ◽  
pp. 209-230 ◽  
Author(s):  
Aneta Pavlenko

In this paper, I argue that current approaches to modeling of concepts in bilingual memory privilege word representation at the expense of concept representation. I identify four problems with the study of concepts in bilingual memory: conflation of semantic and conceptual levels of representation; scarcity of methods targeting conceptual representation; assumption of the static nature of the conceptual store; and insufficient acknowledgment of linguistic and cultural specificity of concepts. Basing my arguments on recent developments in the fields of neurolinguistics, linguistics, psychology, linguistic anthropology, and second language acquisition, I suggest new approaches to the study of concepts in bilingualism, based on notions of concept comparability and concept encoding. Subsequently, I discuss various ways in which concepts could develop and interact with each other in bilingual memory and address possible individual, psycholinguistic, and sociolinguistic constraints on conceptual representation and interaction in bilingual memory.


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