Recent Developments and New Approaches in Mechanical and Chemical Gasketing

1981 ◽  
Author(s):  
Daniel E. Czernik
1999 ◽  
Vol 2 (3) ◽  
pp. 209-230 ◽  
Author(s):  
Aneta Pavlenko

In this paper, I argue that current approaches to modeling of concepts in bilingual memory privilege word representation at the expense of concept representation. I identify four problems with the study of concepts in bilingual memory: conflation of semantic and conceptual levels of representation; scarcity of methods targeting conceptual representation; assumption of the static nature of the conceptual store; and insufficient acknowledgment of linguistic and cultural specificity of concepts. Basing my arguments on recent developments in the fields of neurolinguistics, linguistics, psychology, linguistic anthropology, and second language acquisition, I suggest new approaches to the study of concepts in bilingualism, based on notions of concept comparability and concept encoding. Subsequently, I discuss various ways in which concepts could develop and interact with each other in bilingual memory and address possible individual, psycholinguistic, and sociolinguistic constraints on conceptual representation and interaction in bilingual memory.


Synthesis ◽  
2021 ◽  
Author(s):  
Weilong Liu ◽  
Nicolas Winssinger

The α-exo-methylene-γ-butyrolactone moiety is present in a vast array of structurally diverse natural products and is often central to their biological activity. In this review, we summarize new approaches to α-exo-methylene-γ-butyrolactones developed over the past decade as well as their applications in total synthesis.


2020 ◽  
Vol 29 (2) ◽  
pp. 106-114
Author(s):  
Armin Grunwald ◽  
Martina Schäfer ◽  
Matthias Bergmann

Das Feld der transdisziplinären Forschung wird zusehends unübersichtlicher. Neben Reallaboren werden vielfältige neue Formate wie Fortschrittskollegs (akademische Qualifizierung), Innovationsgruppen (Bereitstellung von Innovationen) und Citizen Science (neue Verhältnisse von Wissenschaft und Gesellschaft) erprobt. Der Beitrag schafft Überblick und Orientierung und reflektiert ,,Neuheit“ und Erwartungen an spezifische Wirkungen der Formate.Transdisciplinary research has gained new momentum in recent years. Several new research formats have been developed and tested, primarily motivated by new funding opportunities, and based on new initiatives from research communities. These new formats comprise real-world lab research, new approaches to academic qualification, new approaches to innovation co-development, and the exploration of new relationships between science and society. In this paper, we considered real-world labs, advanced graduate schools, innovation groups and recent developments in the field of citizen science. We analyzed and compared these formats with respect to their novelty in an effort to develop and explore overarching hypotheses for transdisciplinary research, for example, with respect to potentials and paths of impact. This was all done with the aim of creating oversight to promote further conceptual development in the increasingly fragmented field of transdisciplinary research.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1123
Author(s):  
Maydelid Trujillo-Nolasco ◽  
Enrique Morales-Avila ◽  
Pedro Cruz-Nova ◽  
Kattesh V. Katti ◽  
Blanca Ocampo-García

The application of nanotechnology in nuclear medicine offers attractive therapeutic opportunities for the treatment of various diseases, including cancer. Indeed, nanoparticles-conjugated targeted alpha-particle therapy (TAT) would be ideal for localized cell killing due to high linear energy transfer and short ranges of alpha emitters. New approaches in radiolabeling are necessary because chemical radiolabeling techniques are rendered sub-optimal due to the presence of recoil energy generated by alpha decay, which causes chemical bonds to break. This review attempts to cover, in a concise fashion, various aspects of physics, radiobiology, and production of alpha emitters, as well as highlight the main problems they present, with possible new approaches to mitigate those problems. Special emphasis is placed on the strategies proposed for managing recoil energy. We will also provide an account of the recent studies in vitro and in vivo preclinical investigations of α-particle therapy delivered by various nanosystems from different materials, including inorganic nanoparticles, liposomes, and polymersomes, and some carbon-based systems are also summarized.


2006 ◽  
Vol 11 (2) ◽  
pp. 261-267
Author(s):  
Michel Wieviorka

In this paper, the author seeks to approach contemporary violence in its most different expressions, including the use of the most recent developments in biology, bacteriology, chemistry and nuclear physics. The central idea is that violence changes, and with it the way it is perceived and how we react to it. The text, besides putting violence into a historical context, analyzes 1) the big transformation(s) in the world: the end of the cold war, the new industrial structure and its consequences for the decline of the labor movement, globalization and the new forms of victimization; 2) in the second part, the author points to new approaches and characterizes novel contemporary subjects.


2009 ◽  
Vol 6 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Peter Koller ◽  
Liam Cashman

AbstractIt is widely acknowledged that only by ensuring the correct implementation of European environmental law will it be possible to achieve the EU's ambitious environmental objectives. Implementation has therefore become a strategic priority for the European Commission in recent years. This article presents a short overview of the main challenges in implementing EC environmental law and the Commission's compliance promotion and legal enforcement activities in this field. It deals with the Commission's priority-setting for its legal enforcement actions and presents briefly recent developments and new approaches in the Commission's complaints and infringements handling.


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