Identification of the component responsible for the effects of added dietary copper sulphate in the female domestic fowl

1981 ◽  
Vol 32 (11) ◽  
pp. 1047-1056 ◽  
Author(s):  
Norman Jackson ◽  
Mary H. Stevenson
1961 ◽  
Vol 12 (4) ◽  
pp. 743 ◽  
Author(s):  
AB Beck

Experiments have been carried out to determine whether the concentration of copper in the liver of the domestic fowl and duck can be raised by a moderate increase of dietary copper. Groups of both species were fed for 12 weeks on the same basal diet, to which was added copper sulphate to increase the copper intake two- and fivefold. No significant increase in the liver copper concentration was noted in either species. When copper was administered to both species by intravenous injection, it was rapidly excreted. mostly in the bile. In the fowl a significant amount was excreted through the caeca, but the experiments did not suggest that these organs were important in controlling copper storage. 5tudies on the relationship between h e r copper storage and age showed that there was a rapid increase in the duck after 3 weeks of age. No such changes were observed in the foul


1990 ◽  
Vol 115 (2) ◽  
pp. 291-293 ◽  
Author(s):  
A. L. Yannakopoulos ◽  
A. S. Tserveni-Gousi ◽  
G. Zervas

SUMMARYThe effect of 200, 400 and 600 mg dietary copper sulphate/kg was studied in 64 Japanese quail (Coturnix coturnix japonica) in 1987. The results indicated that addition of 200 or 400 mg/kg to conventional diets of quail 7–42 days old significantly increased (P < 0·05) body weight gain and significantly decreased (P < 0·05) feed intake. There were significant (P < 0·05) increases in carcass, breast and leg weights in some cases; the first two characters had the highest values in the quail fed the diet containing 200 mg Cu/kg. The addition of 600 mg Cu/kg to the diet had an adverse effect on liver weight compared with the addition of 200 and 400 mg/kg. Copper concentration in the liver was not influenced by any rate of copper supplementation.


1981 ◽  
Vol 46 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Mary H. Stevenson ◽  
N. Jackson

1. An experiment is reported in which the effects of giving copper sulphate-supplemented diets and control unsupplemented pair-fed diets to laying hens were compared.2. The level of food intake significantly adversely affected mean body-weight, egg number, egg weight, liver, kidney, oviduct and ovary weights. Gizzard weight/kg body-weight was significantly increased both with decreasing levels of food intake and increased CuSO4 supplementation.3. There was evidence of a depressing effect of CuSO4per se on egg production and possibly on oviduct and ovary weight.4. Liver lipid concentration was significantly decreased with decreasing levels of food intake and the results also suggest a depressing effect of CuSO4.5. The Cu concentrations and total contents in liver and kidneys were significantly increased by dietary added CuSO4. Liver and kidney Zn and Fe concentrations were increased with decreasing levels of food intake rather than by CuSO4. addition.


2019 ◽  
Vol 19 (3) ◽  
pp. 663-677
Author(s):  
Katarzyna Ognik ◽  
Ewelina Cholewińska ◽  
Anna Stępniowska ◽  
Aleksandra Drażbo ◽  
Krzysztof Kozłowski ◽  
...  

AbstractThe aim of the study was to determine what dosage of copper nanoparticles added in the form of a hydrocolloid to standard dietary supplementation with copper sulphate will increase the antioxidant potential in the liver and breast muscle of chickens. In total, 126 one-day-old Ross 308 chickens were assigned to 7 experimental groups of 18 birds each (3 replications of 6 individuals each). The basal-diet treatment did not receive nano-Cu. Experimental groups received nano-Cu (0.5, 1.0 or 1.5 mg/kg body weight per day) via a tube into the crop over three 3-day periods (days 8–10, 22–24 and 36–38) or three 7-day periods (days 8–14, 22–28 and 36–42). Dietary supplementation of chickens with nano-Cu to exceed the Cu level recommended by the NRC increased the content of Cu (P=0.042) while reducing that of Zn in the liver (P=0.031) and breast muscle (P=0.036). Supplementing the diet of chickens with nano-Cu to a level exceeding the level of copper recommended by the NRC by 7% to 25% increased the antioxidant potential of the liver and the breast meat. The study has shown that the antioxidant status of the liver and breast meat of chickens can be improved by supplementing the standard dietary copper sulphate supplement with the addition of nano-Cu, but to a level not exceeding 25% of the copper content recommended by NRC (1994) for broiler chickens, but the most safe is the nano-Cu level not exceeding 7% of the copper content recommended by NRC (1994).


Author(s):  
Alfredo Feria-Velasco ◽  
Guadalupe Tapia-Arizmendi

The fine structure of the Harderian gland has been described in some animal species (hamster, rabbit, mouse, domestic fowl and albino rats). There are only two reports in the literature dealing on the ultrastructure of rat Harderian gland in adult animals. In one of them the author describes the myoepithelial cells in methacrylate-embbeded tissue, and the other deals with the maturation of the acinar cells and the formation of the secretory droplets. The aim of the present work is to analize the relationships among the acinar cell components and to describe the two types of cells located at the perifery of the acini.


Author(s):  
U. Bielenberg

Copper deficiency can cause cardiovascular lesions in experimental animals. Previous experiments have shown that the biochemical and itDrphologic lesions induced by deprivation of dietary copper can be suppressed by feeding diets containing starch or can be magnified by a high sucrose diet. In a recent study it was found that the more severe signs of copper deficiency in rats fed sucrose as compared to starch were due to the fructose moiety of sucrose. Although fructose as compared to starch markedly enhanced the symptoms of copper deficiency, the possibility that an effect of dietary carbohydrates due to the nature of the simple carbohydrate (fructose vs glucose) cannot be excluded. The present study was designed to determine if the severity of copper deficiency in rats fed sucrose as compared to starch is due to the glucose as well as the fructose moiety of sucrose. This portion of the study assessed the morphologic changes in aortas of seventy weanling male rats who were fed, for 9 weeks, copper deficient or copper supplemented diets containing either 62% starch, fructose or glucose. The starch-fed copper supplemented group served as the most normal controls. Rats were sacrificed after 9 weeks of dietary treatments. Copper deficiency was verified by reduced serum ceruloplasmin activity and serum and hepatic copper concentration.


2002 ◽  
Author(s):  
Rebecca A. Sheffield ◽  
Pamela A. Komassa ◽  
Michael R. Baker

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