Fragrance Compounds and Essential Oils with Sedative Effects upon Inhalation

1993 ◽  
Vol 82 (6) ◽  
pp. 660-664 ◽  
Author(s):  
Gerhard Buchbauer ◽  
Leopold Jirovetz ◽  
Walter Jäger ◽  
Christine Plank ◽  
Hermann Dietrich
2005 ◽  
Vol 28 (7) ◽  
pp. 770-774 ◽  
Author(s):  
Won Churl Lim ◽  
Jeong Min Seo ◽  
Chun Il Lee ◽  
Hyeong Bae Pyo ◽  
Bum Chun Lee

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Eduardo Rodrigues da Silva ◽  
Danilo Ribeiro de Oliveira ◽  
Patrícia Dias Fernandes ◽  
Humberto Ribeiro Bizzo ◽  
Suzana Guimarães Leitão

Background.Breuis an aromatic oleoresin which has been used by Amazonian traditional communities as a remedy for headaches and migraines by burning and inhaling the smoke produced during its combustion. This study evaluated the antinociceptive and sedative activities of formulations containingbreuessential oils administered by inhalation.Methods. Five different formulations (A–E) containingbreuessential oils were evaluated for their sedative and antinociceptive activities in mice. They were delivered for 20 minutes using an inhalation chamber coupled with a nebulizer and the air inside was collected by static headspace and analyzed by GC-FID.Results. All nebulized formulations had similar chemical compositions and major compounds as the original essential oils. None of them resulted in significant increase in response time during the hot plate test. In the formalin test, Formulation E showed a significant inhibition of licking responses in the early (46.8%) and late (60.2%) phases. Formulation B was effective (36.9%) in the first phase and Formulation D (37.9%) in the second. None of the formulations presented sedative effects.Conclusion.Breuessential oils, when inhaled, may present antinociceptive and anti-inflammatory properties without sedation. Additionally, nebulization proved to be an efficient method for administration of formulations containing these essential oils.


2020 ◽  
Vol 68 (1) ◽  
Author(s):  
Mailen Ortega Cuadros ◽  
Emma E Acosta de Guevara ◽  
Ailen D Molina Castillo ◽  
Clara Gutiérrez Castañeda ◽  
Glorismar Castro Amarís ◽  
...  

Introduction: Lippia alba is an aromatic species belonging to the Verbenaceae family. Its essential oils have been used in different industries, because of its biological properties. Objective: Identify the perspectives of the biotechnological applications of Lippia alba essential oils. Methodology: A scoping review was conducted on the biological activity of Lippia alba essential oils registered until October, 2018 in EBSCO, Embase, Scopus, and Lilacs databases. Results: Chemotypes I and III have been reported for different biological activities from the evaluations performed on microorganisms, fish, arthropods, small mammals, and cell lines; fundamentally associated with antibacterial, antifungal, cytotoxic, antioxidant, and sedative effects, among others. Records focused mainly on the health, fishing industry, and agrifood sectors. Conclusion: Studies on the effect of essential oil are promising, but do not reflect a continuity of the research toward prototypes or finished commercial products. Research groups must unify evaluation methodologies and include in all studies the relationship between phytochemical and biological activity for the meta-analyses to be possible. Likewise, they must join efforts through the National System for Agricultural Innovation (SNIA, for the term in Spanish) to generate finished products that impact upon society and facilitate progress in the country’s bio-economy.


2011 ◽  
Vol 50 (1) ◽  
pp. 113-119 ◽  
Author(s):  
J. Ascari ◽  
S.L. Sens ◽  
D.S. Nunes ◽  
A. Wisniewski ◽  
M.D. Arbo ◽  
...  

2017 ◽  
Vol 30 (1) ◽  
pp. 56-68 ◽  
Author(s):  
Kenichi Tomi ◽  
Makiko Kitao ◽  
Hiroshi Murakami ◽  
Yasuki Matsumura ◽  
Takahiro Hayashi

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