Stimulative and sedative effects of essential oils upon inhalation in mice

Won Churl Lim; Jeong Min Seo; Chun Il Lee; Hyeong Bae Pyo; Bum Chun Lee

doi:10.1007/bf02977341

Stimulative and sedative effects of essential oils upon inhalation in mice

Archives of Pharmacal Research ◽

10.1007/bf02977341 ◽

2005 ◽

Vol 28 (7) ◽

pp. 770-774 ◽

Cited By ~ 22

Author(s):

Won Churl Lim ◽

Jeong Min Seo ◽

Chun Il Lee ◽

Hyeong Bae Pyo ◽

Bum Chun Lee

Keyword(s):

Essential Oils ◽

Sedative Effects

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Fragrance Compounds and Essential Oils with Sedative Effects upon Inhalation

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600820623 ◽

1993 ◽

Vol 82 (6) ◽

pp. 660-664 ◽

Cited By ~ 205

Author(s):

Gerhard Buchbauer ◽

Leopold Jirovetz ◽

Walter Jäger ◽

Christine Plank ◽

Hermann Dietrich

Keyword(s):

Essential Oils ◽

Sedative Effects ◽

Fragrance Compounds

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Ethnopharmacological Evaluation ofBreuEssential Oils fromProtiumSpecies Administered by Inhalation

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2017/2924171 ◽

2017 ◽

Vol 2017 ◽

pp. 1-10 ◽

Cited By ~ 4

Author(s):

Eduardo Rodrigues da Silva ◽

Danilo Ribeiro de Oliveira ◽

Patrícia Dias Fernandes ◽

Humberto Ribeiro Bizzo ◽

Suzana Guimarães Leitão

Keyword(s):

Essential Oils ◽

Formalin Test ◽

Significant Inhibition ◽

Chemical Compositions ◽

Static Headspace ◽

Hot Plate ◽

Hot Plate Test ◽

Test Formulation ◽

Similar Chemical ◽

Sedative Effects

Background.Breuis an aromatic oleoresin which has been used by Amazonian traditional communities as a remedy for headaches and migraines by burning and inhaling the smoke produced during its combustion. This study evaluated the antinociceptive and sedative activities of formulations containingbreuessential oils administered by inhalation.Methods. Five different formulations (A–E) containingbreuessential oils were evaluated for their sedative and antinociceptive activities in mice. They were delivered for 20 minutes using an inhalation chamber coupled with a nebulizer and the air inside was collected by static headspace and analyzed by GC-FID.Results. All nebulized formulations had similar chemical compositions and major compounds as the original essential oils. None of them resulted in significant increase in response time during the hot plate test. In the formalin test, Formulation E showed a significant inhibition of licking responses in the early (46.8%) and late (60.2%) phases. Formulation B was effective (36.9%) in the first phase and Formulation D (37.9%) in the second. None of the formulations presented sedative effects.Conclusion.Breuessential oils, when inhaled, may present antinociceptive and anti-inflammatory properties without sedation. Additionally, nebulization proved to be an efficient method for administration of formulations containing these essential oils.

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Essential oils biological activity of the Lippia alba (Verbenaceae) shrub

Revista de Biología Tropical ◽

10.15517/rbt.v68i1.39153 ◽

2020 ◽

Vol 68 (1) ◽

Author(s):

Mailen Ortega Cuadros ◽

Emma E Acosta de Guevara ◽

Ailen D Molina Castillo ◽

Clara Gutiérrez Castañeda ◽

Glorismar Castro Amarís ◽

...

Keyword(s):

Biological Activity ◽

Essential Oils ◽

Biological Activities ◽

Biological Properties ◽

Research Groups ◽

Lippia Alba ◽

Sedative Effects ◽

Aromatic Species ◽

Meta Analyses ◽

The Relationship

Introduction: Lippia alba is an aromatic species belonging to the Verbenaceae family. Its essential oils have been used in different industries, because of its biological properties. Objective: Identify the perspectives of the biotechnological applications of Lippia alba essential oils. Methodology: A scoping review was conducted on the biological activity of Lippia alba essential oils registered until October, 2018 in EBSCO, Embase, Scopus, and Lilacs databases. Results: Chemotypes I and III have been reported for different biological activities from the evaluations performed on microorganisms, fish, arthropods, small mammals, and cell lines; fundamentally associated with antibacterial, antifungal, cytotoxic, antioxidant, and sedative effects, among others. Records focused mainly on the health, fishing industry, and agrifood sectors. Conclusion: Studies on the effect of essential oil are promising, but do not reflect a continuity of the research toward prototypes or finished commercial products. Research groups must unify evaluation methodologies and include in all studies the relationship between phytochemical and biological activity for the meta-analyses to be possible. Likewise, they must join efforts through the National System for Agricultural Innovation (SNIA, for the term in Spanish) to generate finished products that impact upon society and facilitate progress in the country’s bio-economy.

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