scholarly journals An on‐site preparable, novel bone‐grafting complex consisting of human platelet‐rich fibrin and porous particles made of a recombinant collagen‐like protein

2018 ◽  
Vol 107 (5) ◽  
pp. 1420-1430 ◽  
Author(s):  
Tsuneyuki Tsukioka ◽  
Takahiro Hiratsuka ◽  
Masayuki Nakamura ◽  
Taisuke Watanabe ◽  
Yutaka Kitamura ◽  
...  
Keyword(s):  
Bone Grafting ◽  
Human Platelet ◽  
Porous Particles ◽  
Platelet Rich Fibrin

scholarly journals Histological and Histomorphometric Evaluation of Applying a Bioactive Advanced Platelet-Rich Fibrin to a Perforated Schneiderian Membrane in a Maxillary Sinus Elevation Model

2020 ◽  
Vol 8 ◽  
Author(s):  
Liangjing Xin ◽  
Shuai Yuan ◽  
Zhixiang Mu ◽  
Dize Li ◽  
Jinlin Song ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Bone Grafting ◽  
Major Complication ◽  
Collagen Membrane ◽  
Bovine Bone ◽  
Schneiderian Membrane ◽  
Platelet Rich Fibrin ◽  
Tissue Healing ◽  
Group A ◽  
Elevation Model

BackgroundSchneiderian membrane (SM) perforation is a major complication of maxillary sinus elevation with simultaneous bone grafting, yet under this scenario there is no standard biomaterial that maximizes favorable tissue healing and osteogenic effects.PurposeTo compare the effect of advanced platelet-rich fibrin (A-PRF) and collagen membrane (CM) on a perforated SM with simultaneous bone grafting in a maxillary sinus elevation model.Materials and MethodsAfter perforation of the SM was established, 24 animals were randomly divided into two groups: (i) group CM: CM and deproteinized bovine bone mineral (DBBM) (n = 12), (ii) group A-PRF: A-PRF and DBBM (n = 12). Radiographic and histological evaluations were performed at 1 and 4 weeks post-operation.ResultsAt 1 week, an intact SM was found in group A-PRF. At each time point, the number of inflammatory cells at the perforated site was higher in group CM, and the area of new osteoid formation was significantly greater in group A-PRF (p < 0.0001). At 4 weeks, the osteogenic pattern was shown as from the periphery to the center of the sinus cavity in group A-PRF.ConclusionThe higher elasticity, matching degradability, and plentiful growth factors of A-PRF resulted in a fully repaired SM, which later ensured the two osteogenic sources from the SM to generate significant new bone formation. Thus, A-PRF can be considered to be a useful bioactive tissue-healing biomaterial for SM perforation with simultaneous bone grafting.

scholarly journals Efficacy of Platelet-Rich Fibrin in Secondary Cleft Alveolar Bone Grafting

2019 ◽  
Vol 3 (1) ◽  
pp. s-0039-1678672 ◽  
Author(s):  
Anil Kumar Desai ◽  
Niranjan Kumar ◽  
Punit Dikhit ◽  
Srikanth B. Koikude ◽  
Saurav Bhaduri
Keyword(s):  
Bone Grafting ◽  
Alveolar Bone ◽  
Iliac Bone ◽  
Autogenous Bone ◽  
Platelet Rich Fibrin ◽  
Alveolar Bone Grafting ◽  
Osteogenic Effect ◽  
Group 2 ◽  
Secondary Alveolar Bone Grafting ◽  
Group 1

The main objective of this article is to evaluate the efficacy of platelet-rich fibrin (PRF) for secondary alveolar bone grafting. Patients between 9 and 14 years of age were included in study and were divided in two groups: Group 1—iliac bone with PRF and group 2—iliac bone without PRF. Radiographic assessment was done preoperatively, immediate postoperatively, and at 3, 6, and 9 months, respectively. Vertical bone height was assessed using 4-point scale. In group 1, 14 patients showed grade 1 resorption at 3 months and at 6 and 9 months all patients showed grade 1 resorption. In group 2, 16 patients had grade 1 resorption at 3 months, 2 patients had grade 2 resorption at 6 months, and 6 patients had grade 2 resorption at 9 months. Use of PRF growth factor with autogenous bone results in greater osteogenic effect which increases new bone regeneration and better wound healing.

scholarly journals A split-face of dermaroller and intradermal injection with the autologous platelet rich fibrin lysate in the treatment of exogenous ocronosis: A case series

2019 ◽  
Author(s):  
Moerbono Mochtar ◽  
Sri Esa Ilona ◽  
Dendy Zulfikar ◽  
Ammarilis Murastami ◽  
Suci Widhiati
Keyword(s):  
Patient Satisfaction ◽  
Human Platelet ◽  
Case Series ◽  
Intradermal Injection ◽  
Mixed Result ◽  
Platelet Rich Fibrin ◽  
Grading Scale ◽  
Autologous Platelet ◽  
Split Face

Exogenous ochronosis (EO) is a rare, cosmetically disfiguring condition, resulting from the long term use of topical hydroquinone in treatment of melasma. The studies about it are small and many of the treatments have mixed result. Autologous human platelet rich fibrin (PRF-L) is contains platelet that are purpose to release numerous growth factor that valuable in numerous dermatologic application.Platelet rich fibrin lysate used for EO has not been reported. We presented three cases with EO treated with split-face of the PRF-L applied right before dermaroller on right face and intradermal injection on the left for 8 weeks.The treatment re-apply every 2 weeks. The improvement was measuring by 10-point grading scale and dermoscopic examination, including five-point grading scale to assessment of patient satisfaction. All of three patients demonstrated significant improvementand very satisfied in 4th week of treatment. This result suggests that PRF-L can be used as of one modality for EO treatment.

Effects of leukocyte–platelet-rich fibrin (L-PRF) in different intraoral bone grafting procedures: a systematic review

2019 ◽  
Vol 48 (2) ◽  
pp. 250-262 ◽  
Author(s):  
P. Dragonas ◽  
T. Katsaros ◽  
G. Avila-Ortiz ◽  
L. Chambrone ◽  
J.H. Schiavo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Grafting ◽  
Platelet Rich Fibrin

scholarly journals Clinical and radiographic evaluation of platelet-rich fibrin as an adjunct to bone grafting demineralized freeze-dried bone allograft in intrabony defects

2020 ◽  
Vol 24 (1) ◽  
pp. 60 ◽  
Author(s):  
Abhinav Atchuta ◽  
JagadishReddy Gooty ◽  
VikramReddy Guntakandla ◽  
SunilKumar Palakuru ◽  
Satyanarayana Durvasula ◽  
...  
Keyword(s):  
Bone Grafting ◽  
Bone Allograft ◽  
Radiographic Evaluation ◽  
Intrabony Defects ◽  
Platelet Rich Fibrin ◽  
Freeze Dried

Incorporation of exudates of human platelet-rich fibrin gel in biodegradable fibrin scaffolds for tissue engineering of cartilage

2012 ◽  
Vol 100B (4) ◽  
pp. 948-955 ◽  
Author(s):  
Chi-Sheng Chien ◽  
Hsiu-O Ho ◽  
Yu-Chih Liang ◽  
Pai-Hung Ko ◽  
Ming-Thau Sheu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Human Platelet ◽  
Fibrin Gel ◽  
Platelet Rich Fibrin
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