scholarly journals The Use of Platelet-Rich Fibrin in Bone Grafting

Author(s):  
Belir Atalay ◽  
Ozge Doganay
Author(s):  
Liangjing Xin ◽  
Shuai Yuan ◽  
Zhixiang Mu ◽  
Dize Li ◽  
Jinlin Song ◽  
...  

BackgroundSchneiderian membrane (SM) perforation is a major complication of maxillary sinus elevation with simultaneous bone grafting, yet under this scenario there is no standard biomaterial that maximizes favorable tissue healing and osteogenic effects.PurposeTo compare the effect of advanced platelet-rich fibrin (A-PRF) and collagen membrane (CM) on a perforated SM with simultaneous bone grafting in a maxillary sinus elevation model.Materials and MethodsAfter perforation of the SM was established, 24 animals were randomly divided into two groups: (i) group CM: CM and deproteinized bovine bone mineral (DBBM) (n = 12), (ii) group A-PRF: A-PRF and DBBM (n = 12). Radiographic and histological evaluations were performed at 1 and 4 weeks post-operation.ResultsAt 1 week, an intact SM was found in group A-PRF. At each time point, the number of inflammatory cells at the perforated site was higher in group CM, and the area of new osteoid formation was significantly greater in group A-PRF (p < 0.0001). At 4 weeks, the osteogenic pattern was shown as from the periphery to the center of the sinus cavity in group A-PRF.ConclusionThe higher elasticity, matching degradability, and plentiful growth factors of A-PRF resulted in a fully repaired SM, which later ensured the two osteogenic sources from the SM to generate significant new bone formation. Thus, A-PRF can be considered to be a useful bioactive tissue-healing biomaterial for SM perforation with simultaneous bone grafting.


2019 ◽  
Vol 3 (1) ◽  
pp. s-0039-1678672 ◽  
Author(s):  
Anil Kumar Desai ◽  
Niranjan Kumar ◽  
Punit Dikhit ◽  
Srikanth B. Koikude ◽  
Saurav Bhaduri

The main objective of this article is to evaluate the efficacy of platelet-rich fibrin (PRF) for secondary alveolar bone grafting. Patients between 9 and 14 years of age were included in study and were divided in two groups: Group 1—iliac bone with PRF and group 2—iliac bone without PRF. Radiographic assessment was done preoperatively, immediate postoperatively, and at 3, 6, and 9 months, respectively. Vertical bone height was assessed using 4-point scale. In group 1, 14 patients showed grade 1 resorption at 3 months and at 6 and 9 months all patients showed grade 1 resorption. In group 2, 16 patients had grade 1 resorption at 3 months, 2 patients had grade 2 resorption at 6 months, and 6 patients had grade 2 resorption at 9 months. Use of PRF growth factor with autogenous bone results in greater osteogenic effect which increases new bone regeneration and better wound healing.


2018 ◽  
Vol 107 (5) ◽  
pp. 1420-1430 ◽  
Author(s):  
Tsuneyuki Tsukioka ◽  
Takahiro Hiratsuka ◽  
Masayuki Nakamura ◽  
Taisuke Watanabe ◽  
Yutaka Kitamura ◽  
...  

2019 ◽  
Vol 48 (2) ◽  
pp. 250-262 ◽  
Author(s):  
P. Dragonas ◽  
T. Katsaros ◽  
G. Avila-Ortiz ◽  
L. Chambrone ◽  
J.H. Schiavo ◽  
...  

2020 ◽  
Vol 24 (1) ◽  
pp. 60 ◽  
Author(s):  
Abhinav Atchuta ◽  
JagadishReddy Gooty ◽  
VikramReddy Guntakandla ◽  
SunilKumar Palakuru ◽  
Satyanarayana Durvasula ◽  
...  

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