scholarly journals Speckle contrast diffuse correlation tomography of cerebral blood flow in perinatal disease model of neonatal piglets

2021 ◽  
Author(s):  
Chong Huang ◽  
Siavash Mazdeyasna ◽  
Mehrana Mohtasebi ◽  
Kathryn E. Saatman ◽  
Qiang Cheng ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Disease Model ◽  
Speckle Contrast ◽  
Neonatal Piglets

Cerebral Blood Flow and Metabolism in Fasting Neonatal Piglets

Neonatology ◽  
1989 ◽  
Vol 55 (4-5) ◽  
pp. 275-280 ◽  
Author(s):  
P.A. Flecknell ◽  
W. Wootton
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Neonatal Piglets

Cerebral Blood Flow and Cerebral Metabolism in Normal and Intrauterine Growth Retarded Neonatal Piglets

1983 ◽  
Vol 64 (2) ◽  
pp. 161-165 ◽  
Author(s):  
P. A. Flecknell ◽  
R. Wootton ◽  
Muriel John
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Partition Coefficient ◽  
Cerebral Metabolism ◽  
Liver Weight ◽  
Arterial Oxygen ◽  
Intrauterine Growth ◽  
Neonatal Piglets ◽  
Fick Principle ◽  
The Brain

1. Cerebral blood flow and cerebral metabolism were measured in conscious, normally grown neonatal piglets and in littermates which had undergone intrauterine growth retardation. 2. Cerebral blood flow was measured by the Kety-Schmidt technique using [125I]iodoantipyrine as the tracer. The tissue: blood partition coefficient of this tracer was measured in separate groups of growth retarded and normal animals. Cerebral utilization rates of glucose and oxygen were calculated from the arteriovenous concentration differences on the Fick principle. 3. The mean body weight of the growth retarded animals was about half that of their normally grown littermates, and liver weight was reduced in proportion. Brain weight was slightly but significantly lower in the growth retarded animals. 4. Cerebral blood flow was lower in the growth retarded piglets but the rates of cerebral utilization of oxygen and glucose were not significantly different in the two groups. The fractional extraction of arterial oxygen by the brain was significantly higher in the growth retarded animals. 5. The partition coefficient of ipdoantipyrine was significantly lower in the growth retarded animals, being about 75% of the normal value. It is clear that had the partition coefficients been assumed to have been the same in both groups the calculated cerebral blood flows would have been identical. 6. It is concluded that growth retarded neonatal piglets have relatively normal sized brains, with a rate of glucose and oxygen consumption that is not significantly different from normal, despite a reduction in cerebral blood flow of about 35%. Consequently the fractional extraction rate of arterial oxygen by the brain is increased from 50% to 70%.

Intraoperative laser speckle contrast imaging for monitoring cerebral blood flow: results from a 10-patient pilot study

2012 ◽  
Author(s):  
Lisa M. Richards ◽  
Erica L. Weber ◽  
Ashwin B. Parthasarathy ◽  
Kaelyn L. Kappeler ◽  
Douglas J. Fox ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Pilot Study ◽  
Laser Speckle ◽  
Contrast Imaging ◽  
Laser Speckle Contrast Imaging ◽  
Speckle Contrast
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