Histopathology as a tool for the evaluation of endocrine disruption in zebrafish (Danio rerio)

2003 ◽  
Vol 22 (4) ◽  
pp. 908-913 ◽  
Author(s):  
Leo T. M. van der Ven ◽  
Piet W. Wester ◽  
Jeff G. Vos
2019 ◽  
Vol 9 (7) ◽  
pp. 1362 ◽  
Author(s):  
Chunhong Shi ◽  
Yide He ◽  
Jiaxin Liu ◽  
Yue Lu ◽  
Yuting Fan ◽  
...  

In aquatic environments, organisms are exposed to mixtures of pollutants which may change the toxicity profile of each contaminant, compared to its toxicity alone. Carbamazepine (CBZ) and cadmium (Cd) are among the pollutants that co-occur in aquatic environments. To date, most research about their toxicity towards aquatic vertebrates is based on single exposure experiments. The present study aims to evaluate single and combined effects of CBZ and Cd on biomarkers in female Danio rerio (zebrafish) by exposing them to environmentally relevant concentrations of these two pollutants for ten days. Four kinds of biomarkers involved in antioxidant systems, energy metabolism, nervous system, and endocrine disruption, respectively, were studied. Our research results coincided with those of former studies in single exposure experiments. However, the combined exposure of CBZ and Cd exerted different responses from other studies in which these two contaminants were examined alone in zebrafish. The present study evidenced the need to conduct more coexposure studies to enhance the environmental relevance of these experimental results.


2020 ◽  
Vol 184 ◽  
pp. 109310 ◽  
Author(s):  
Miaomiao Teng ◽  
Chen Wang ◽  
Min Song ◽  
Xiangguang Chen ◽  
Jie Zhang ◽  
...  

Chemosphere ◽  
2020 ◽  
Vol 240 ◽  
pp. 124970 ◽  
Author(s):  
Steve U. Ayobahan ◽  
Sebastian Eilebrecht ◽  
Lisa Baumann ◽  
Matthias Teigeler ◽  
Henner Hollert ◽  
...  

2016 ◽  
Vol 171 ◽  
pp. 48-58 ◽  
Author(s):  
Chen Jianjie ◽  
Xue Wenjuan ◽  
Cao Jinling ◽  
Song Jie ◽  
Jia Ruhui ◽  
...  

2016 ◽  
Vol 48 ◽  
pp. 157-167 ◽  
Author(s):  
Xuesong Zhao ◽  
Xin Ren ◽  
Baixiang Ren ◽  
Zhouying Luo ◽  
Rong Zhu

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