Endocrine disruption effects of long-term exposure to perfluorodecanoic acid (PFDA) and perfluorotridecanoic acid (PFTrDA) in zebrafish (Danio rerio) and related mechanisms

Chemosphere ◽  
2014 ◽  
Vol 108 ◽  
pp. 360-366 ◽  
Author(s):  
Areum Jo ◽  
Kyunghee Ji ◽  
Kyungho Choi
2012 ◽  
Vol 120-121 ◽  
pp. 11-18 ◽  
Author(s):  
Lianguo Chen ◽  
Chenyan Hu ◽  
Changjiang Huang ◽  
Qiangwei Wang ◽  
Xiaofang Wang ◽  
...  
Keyword(s):  

2015 ◽  
Vol 197 ◽  
pp. 278-286 ◽  
Author(s):  
Xiyan Mu ◽  
Kai Wang ◽  
Tingting Chai ◽  
Lizhen Zhu ◽  
Yang Yang ◽  
...  

2021 ◽  
Vol 92 (8) ◽  
pp. A11.2-A11
Author(s):  
Ewelina de Leon ◽  
Graeme Yorston

Objectives/AimsTraumatic brain injury is a common cause of permanent or long-term disability,1 and up to 80% of people with moderate to severe brain injury have some degree of pituitary insufficiency. Endocrine disruption has been documented in medical literature since the 1940s,2-4 where central diabetes insipidus has been described as a common transient complication which causes polydipsia (insatiable thirst). However, polydipsia can be caused by other conditions. It is classified into dipsogenic, in a syndrome of disordered thirst-regulating mechanism in patients without psychiatric disease called dipsogenic diabetes insipidus, psychogenic, as a compulsive water drinking in patients with psychiatric conditions referred to as psychogenic polydipsia or psychogenic diabetes insipidus and iatrogenic where large quantities of water are consumed for health benefits. All of which are referred to as primary polydipsia if these conditions cannot be distinguished. Dipsogenic diabetes insipidus and psychogenic polydipsia can be easily mixed up, misdiagnosed or even unrecognised, mainly because their pathophysiology is still unclear. Are these conditions different, or is there anything that can relate them to each other? With this literature review, we are aiming to find the link between subsets of polydipsia after brain trauma, to compare proposed differential diagnosis and their functionality in clinical settings.MethodA literature review was conducted following a search of MEDLINE, CINAHL Plus, APA PsycArticles, APA PsycBooks, APA PsycInfo databases from 1858 onwards.ResultsWe will present our findings from the literature review.ConclusionPolydipsia is a common clinical problem and requires careful evaluation and management to prevent long term neurological sequelae, and there are no evidence-based treatment guidelines.References National Institute of Health and Care Excellence (NICE). (2019). Head Injury. CG176. Retrieved from: https://www.nice.org.uk/guidance/cg176 Escamilla RF, Lisser H. Simmonds disease: A clinical study with revie of the literature; Differentiation from anorexia nervosa by statistical analysis of 595 cases, 101 of which were provided pathologically. The Journal of Clinical Endocrinology & Metabolism 1942;2(2):6596. Porter RJ, Miller RA. Diabetes insipidus following closed head injury. Journal of Neurology, Neurosurgery, and Psychiatry 1946;11:528562. Webb NE, Little B, Loupee-Wilson S, Power EM. Traumatic brain injury and neuro-endocrine disruption: medical and psychosocial rehabilitation. NeuroRehabilitation (Reading, Mass.) 2014;34(4):625636.


2008 ◽  
Vol 77 (3) ◽  
pp. 455-460 ◽  
Author(s):  
E. Voslářová ◽  
V. Pištěková ◽  
Z. Svobodová ◽  
I. Bedáňová

The aim of this study was to investigate the long-term effects of subchronic exposure to sublethal levels of nitrite, ranging from 15 to 130 mg l-1 NO2-, on growth in aquarium fish Danio rerio. The juvenile growth test according to OECD 215 was used in the experiments. Fish weight was measured at the beginning of the experiment and then using the same method, fish weight was observed 28 days after fish stocking. Compared to the control, growth suppression was detected from the concentration of 73 mg l-1 NO2- (P < 0.05) and a significant inhibition of fish body growth was shown from 130 mg l-1 NO2- (P < 0.01). An exponential relationship between nitrite concentrations and specific growth rate (R2 = 0.896) was detected.


2019 ◽  
Vol 9 (7) ◽  
pp. 1362 ◽  
Author(s):  
Chunhong Shi ◽  
Yide He ◽  
Jiaxin Liu ◽  
Yue Lu ◽  
Yuting Fan ◽  
...  

In aquatic environments, organisms are exposed to mixtures of pollutants which may change the toxicity profile of each contaminant, compared to its toxicity alone. Carbamazepine (CBZ) and cadmium (Cd) are among the pollutants that co-occur in aquatic environments. To date, most research about their toxicity towards aquatic vertebrates is based on single exposure experiments. The present study aims to evaluate single and combined effects of CBZ and Cd on biomarkers in female Danio rerio (zebrafish) by exposing them to environmentally relevant concentrations of these two pollutants for ten days. Four kinds of biomarkers involved in antioxidant systems, energy metabolism, nervous system, and endocrine disruption, respectively, were studied. Our research results coincided with those of former studies in single exposure experiments. However, the combined exposure of CBZ and Cd exerted different responses from other studies in which these two contaminants were examined alone in zebrafish. The present study evidenced the need to conduct more coexposure studies to enhance the environmental relevance of these experimental results.


2020 ◽  
Vol 184 ◽  
pp. 109310 ◽  
Author(s):  
Miaomiao Teng ◽  
Chen Wang ◽  
Min Song ◽  
Xiangguang Chen ◽  
Jie Zhang ◽  
...  

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