Recent developments in PDMS surface modification for microfluidic devices

2010 ◽  
Vol 31 (1) ◽  
pp. 2-16 ◽  
Author(s):  
Jinwen Zhou ◽  
Amanda Vera Ellis ◽  
Nicolas Hans Voelcker
2011 ◽  
Vol 33 (1) ◽  
pp. 89-104 ◽  
Author(s):  
Jinwen Zhou ◽  
Dmitriy A. Khodakov ◽  
Amanda V. Ellis ◽  
Nicolas H. Voelcker

Life ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 53 ◽  
Author(s):  
Hironori Sugiyama ◽  
Taro Toyota

Experimental evolution in chemical models of cells could reveal the fundamental mechanisms of cells today. Various chemical cell models, water-in-oil emulsions, oil-on-water droplets, and vesicles have been constructed in order to conduct research on experimental evolution. In this review, firstly, recent studies with these candidate models are introduced and discussed with regards to the two hierarchical directions of experimental evolution (chemical evolution and evolution of a molecular self-assembly). Secondly, we suggest giant vesicles (GVs), which have diameters larger than 1 µm, as promising chemical cell models for studying experimental evolution. Thirdly, since technical difficulties still exist in conventional GV experiments, recent developments of microfluidic devices to deal with GVs are reviewed with regards to the realization of open-ended evolution in GVs. Finally, as a future perspective, we link the concept of messy chemistry to the promising, unexplored direction of experimental evolution in GVs.


2010 ◽  
Vol 211 (2) ◽  
pp. 195-203 ◽  
Author(s):  
J. D. Jeyaprakash S. Samuel ◽  
Thilo Brenner ◽  
Oswald Prucker ◽  
Markus Grumann ◽  
Jens Ducree ◽  
...  

2002 ◽  
Vol 470 (1) ◽  
pp. 87-99 ◽  
Author(s):  
Steven A Soper ◽  
Alyssa C Henry ◽  
Bikas Vaidya ◽  
Michelle Galloway ◽  
Musundi Wabuyele ◽  
...  

2015 ◽  
Vol 3 (29) ◽  
pp. 6032-6036 ◽  
Author(s):  
Jennifer M. Leung ◽  
Leslie R. Berry ◽  
Helen M. Atkinson ◽  
Rena M. Cornelius ◽  
Darren Sandejas ◽  
...  

PDMS surface for blood oxygenator modified with antithrombin–heparin complexviapolydopamine.


2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Ismail Ab Rahman ◽  
Vejayakumaran Padavettan

Application of silica nanoparticles as fillers in the preparation of nanocomposite of polymers has drawn much attention, due to the increased demand for new materials with improved thermal, mechanical, physical, and chemical properties. Recent developments in the synthesis of monodispersed, narrow-size distribution of nanoparticles by sol-gel method provide significant boost to development of silica-polymer nanocomposites. This paper is written by emphasizing on the synthesis of silica nanoparticles, characterization on size-dependent properties, and surface modification for the preparation of homogeneous nanocomposites, generally by sol-gel technique. The effect of nanosilica on the properties of various types of silica-polymer composites is also summarized.


TECHNOLOGY ◽  
2017 ◽  
Vol 05 (01) ◽  
pp. 1-12 ◽  
Author(s):  
Aslihan Gokaltun ◽  
Martin L. Yarmush ◽  
Ayse Asatekin ◽  
O. Berk Usta

In the last decade microfabrication processes including rapid prototyping techniques have advanced rapidly and achieved a fairly mature stage. These advances have encouraged and enabled the use of microfluidic devices by a wider range of users with applications in biological separations and cell and organoid cultures. Accordingly, a significant current challenge in the field is controlling biomolecular interactions at interfaces and the development of novel biomaterials to satisfy the unique needs of the biomedical applications. Poly(dimethylsiloxane) (PDMS) is one of the most widely used materials in the fabrication of microfluidic devices. The popularity of this material is the result of its low cost, simple fabrication allowing rapid prototyping, high optical transparency, and gas permeability. However, a major drawback of PDMS is its hydrophobicity and fast hydrophobic recovery after surface hydrophilization. This results in significant nonspecific adsorption of proteins as well as small hydrophobic molecules such as therapeutic drugs limiting the utility of PDMS in biomedical microfluidic circuitry. Accordingly, here, we focus on recent advances in surface molecular treatments to prevent fouling of PDMS surfaces towards improving its utility and expanding its use cases in biomedical applications.


2013 ◽  
Vol 8 (6) ◽  
pp. 305-307 ◽  
Author(s):  
Maryam Alsadat Rad ◽  
Kamarulazizi Ibrahim ◽  
Khairudin Mohamed ◽  
Nazalan Najimudin

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