Subcortical brain volume and cortical thickness in adolescent girls and women with binge eating

Author(s):  
Kelsey E. Hagan ◽  
Cara Bohon
2020 ◽  
Vol 274 ◽  
pp. 1201-1205
Author(s):  
Nadia Abdo ◽  
Emily Boyd ◽  
Shaunte Baboumian ◽  
Spiro P. Pantazatos ◽  
Allan Geliebter

2019 ◽  
Vol 85 (10) ◽  
pp. S33 ◽  
Author(s):  
Premika Boedhoe ◽  
Daan van Rooij ◽  
Martine Hoogman ◽  
Lianne Schmaal ◽  
Paul M. Thompson ◽  
...  

2020 ◽  
Vol 177 (9) ◽  
pp. 834-843 ◽  
Author(s):  
Premika S.W. Boedhoe ◽  
Daan van Rooij ◽  
Martine Hoogman ◽  
Jos W.R. Twisk ◽  
Lianne Schmaal ◽  
...  

Stroke ◽  
2020 ◽  
Vol 51 (9) ◽  
Author(s):  
Amy Brodtmann ◽  
Mohamed Salah Khlif ◽  
Natalia Egorova ◽  
Michele Veldsman ◽  
Laura J. Bird ◽  
...  

Background and Purpose: Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification of potential therapeutic windows for interventions to prevent poststroke brain atrophy. Methods: We charted total and regional brain volume and cortical thickness trajectories, comparing atrophy rates over 2 time periods in the first year after ischemic stroke: within 3 months (early period) and between 3 and 12 months (later period). Patients with first-ever or recurrent ischemic stroke were recruited from 3 Melbourne hospitals at 1 of 2 poststroke time points: within 6 weeks (baseline) or 3 months. Whole-brain 3T magnetic resonance imaging was performed at 3 time points: baseline, 3 months, and 12 months. Eighty-six stroke participants completed testing at baseline; 125 at 3 months (76 baseline follow-up plus 49 delayed recruitment); and 113 participants at 12 months. Their data were compared with 40 healthy control participants with identical testing. We examined 5 brain measures: hippocampal volume, thalamic volume, total brain and hemispheric brain volume, and cortical thickness. We tested whether brain atrophy rates differed between time points and groups. A linear mixed-effect model was used to compare brain structural changes, including age, sex, years of education, a composite cerebrovascular risk factor score, and total intracranial volume as covariates. Results: Atrophy rates were greater in stroke than control participants. Ipsilesional hemispheric, hippocampal, and thalamic atrophy rates were 2 to 4 times greater in the early versus later period. Conclusions: Regional atrophy rates vary over the first year after stroke. Rapid brain volume loss in the first 3 months after stroke may represent a potential window for intervention. Registration: URL: https://www.clinicaltrials.gov . Unique identifier: NCT02205424.


1993 ◽  
Vol 699 (1 Prevention an) ◽  
pp. 200-206 ◽  
Author(s):  
R. BERKOWITZ ◽  
A. J. STUNKARD ◽  
V. A. STALLINGS

2018 ◽  
Vol 51 (6) ◽  
pp. 1702450 ◽  
Author(s):  
Sébastien Celle ◽  
Claire Boutet ◽  
Cédric Annweiler ◽  
Jean-Claude Barthélémy ◽  
Frédéric Roche

The link between sleep apnoea and brain structure is unclear; although dysfunction of the hippocampus, middle temporal gyrus and brainstem/cerebellum have been observed previously. However, this link has been little explored in elderly subjects. The aim of this study was to explore the link between sleep apnoea and the brain in an elderly population.226 asymptomatic elderly subjects (age mean±sd 75.3±0.9 years, range 72.3–77.8 years) from the PROOF (Evaluation of Ageing, Autonomic Nervous System Activity and Cardiovascular Events) cohort study were explored using linear voxel-based or cortical thickness with apnoea/hypopnoea index (AHI; mean±sd 15.9±11.5 events·h−1, range 6–63.6 events·h−1) as a covariate of main interest. The brain volumes of 20 control subjects, 18 apnoeic (AHI >29 events·h−1) treated patients and 20 apnoeic untreated patients from this population were compared using voxel-based morphometry, cortical thickness or surface-based analyses.AHI was not associated with any change in local brain volume, cortical thickness or cortex surface. Control subjects, apnoeic treated and untreated patients were not different in terms of local brain volume, cortical thickness or surface.In a specific population of asymptomatic elderly healthy subjects, sleep apnoea does not seem to be associated with a change in local brain volume or in cortical thickness.


2018 ◽  
Vol 18 ◽  
pp. 377-381 ◽  
Author(s):  
Magdalena Wojtowicz ◽  
Andrew J. Gardner ◽  
Peter Stanwell ◽  
Ross Zafonte ◽  
Bradford C. Dickerson ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0235609
Author(s):  
Tiago Gil Oliveira ◽  
Chloe Ifrah ◽  
Roman Fleysher ◽  
Michael Stockman ◽  
Michael L. Lipton

2018 ◽  
Vol 43 (3) ◽  
pp. 151-160 ◽  
Author(s):  
Laura A. Berner ◽  
Mihaela Stefan ◽  
Seonjoo Lee ◽  
Zhishun Wang ◽  
Kate Terranova ◽  
...  

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