scholarly journals Altered cortical thickness and attentional deficits in adolescent girls and women with bulimia nervosa

2018 ◽  
Vol 43 (3) ◽  
pp. 151-160 ◽  
Author(s):  
Laura A. Berner ◽  
Mihaela Stefan ◽  
Seonjoo Lee ◽  
Zhishun Wang ◽  
Kate Terranova ◽  
...  
Keyword(s):  
Bulimia Nervosa ◽  
Adolescent Girls ◽  
Cortical Thickness ◽  
Attentional Deficits

scholarly journals Alterations in cortical thickness and structural connectivity are associated with symptom severity in bulimia nervosa

2017 ◽  
Author(s):  
Margaret L. Westwater ◽  
Jakob Seidlitz ◽  
Kelly M.J. Diederen ◽  
Sarah Fischer ◽  
James C. Thompson
Keyword(s):  
Individual Differences ◽  
Bulimia Nervosa ◽  
Cortical Thickness ◽  
Symptom Severity ◽  
Structural Connectivity ◽  
Temporal Cortex ◽  
Continuous Measure ◽  
Grey Matter Volume ◽  
Adult Women ◽  
Eating Disorder Examination

AbstractBulimia nervosa (BN) is a serious psychiatric illness defined by preoccupation with weight and shape, episodic binge-eating and compensatory behaviors. Although diagnosed BN has been associated with diffuse grey matter volume reductions, characterization of brain structure alterations in women with a range of BN symptoms has yet to be made. This study examined whether changes in cortical thickness (CT) scaled with BN symptom severity in a sample of 33 adult women (n = 10 BN; n = 5 EDNOS-BN). Our second objective was to assess global structural connectivity (SC) of CT and to determine if individual differences in global SC relate to BN symptom severity. We used the validated Eating Disorder Examination Questionnaire (EDE-Q; Fairburn & Beglin, 1994) as a continuous measure of BN symptom severity. Increased EDE-Q score was negatively related to global CT and local CT in the left middle frontal gyrus, right superior frontal gyrus and bilateral orbitofrontal cortex (OFC) and temporoparietal regions. Moreover, analysis of global SC indicated that BN-related cortical thinning preferentially occurred in regions with high global connectivity. Finally, we showed that individuals’ contribution to global SC at the group level were significantly related to EDE-Q score, where increased EDE-Q score correlated with reduced connectivity of the left OFC and middle temporal cortex and increased connectivity of the right superior parietal lobule. Our findings offer novel insight into CT alterations in BN and further suggest that the combination of CT and structural connectivity measures may be sensitive to individual differences in BN symptom severity.

scholarly journals Associations between cortical thickness, structural connectivity and severity of dimensional bulimia nervosa symptomatology

2018 ◽  
Vol 271 ◽  
pp. 118-125 ◽  
Author(s):  
Margaret L. Westwater ◽  
Jakob Seidlitz ◽  
Kelly M.J. Diederen ◽  
Sarah Fischer ◽  
James C. Thompson
Keyword(s):  
Bulimia Nervosa ◽  
Cortical Thickness ◽  
Structural Connectivity

scholarly journals The modelled cost-effectiveness of cognitive dissonance for the prevention of anorexia nervosa and bulimia nervosa in adolescent girls in Australia

2017 ◽  
Vol 50 (7) ◽  
pp. 834-841 ◽  
Author(s):  
Long Khanh-Dao Le ◽  
Jan J. Barendregt ◽  
Phillipa Hay ◽  
Susan M. Sawyer ◽  
Susan J. Paxton ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Cost Effectiveness ◽  
Bulimia Nervosa ◽  
Cognitive Dissonance ◽  
Adolescent Girls
Sign in / Sign up

Export Citation Format

Share Document