Sex differences in the pattern of age-dependent increase in the BMI from 20-59 years

2002 ◽  
Vol 14 (6) ◽  
pp. 693-698 ◽  
Author(s):  
Zygmunt Welon ◽  
Alicja Szklarska ◽  
Tadeusz Bielicki ◽  
Robert M. Malina
Keyword(s):  
Sex Differences ◽  
Age Dependent

Abstract 055: Sex Differences in the Development of Age-Dependent Hypertension and the Salt Sensitivity of Blood Pressure

Hypertension ◽  
2019 ◽  
Vol 74 (Suppl_1) ◽  
Author(s):  
Franco J Puleo ◽  
Alissa A Frame ◽  
Parul Chaudhary ◽  
Richard D Wainford
Keyword(s):  
Blood Pressure ◽  
Sex Differences ◽  
Salt Sensitivity ◽  
Age Dependent

Sex differences in survival of cutaneous melanoma are age dependent

2011 ◽  
Vol 21 (3) ◽  
pp. 244-252 ◽  
Author(s):  
Liljana Mervic ◽  
Ulrike Leiter ◽  
Friedegund Meier ◽  
Thomas Eigentler ◽  
Andrea Forschner ◽  
...  
Keyword(s):  
Sex Differences ◽  
Cutaneous Melanoma ◽  
Age Dependent

scholarly journals Sex differences in the effects of juvenile and adult diet on age-dependent reproductive effort

2015 ◽  
Vol 28 (5) ◽  
pp. 1067-1079 ◽  
Author(s):  
T. M. Houslay ◽  
J. Hunt ◽  
M. C. Tinsley ◽  
L. F. Bussière
Keyword(s):  
Sex Differences ◽  
Reproductive Effort ◽  
Age Dependent ◽  
Adult Diet

Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis

2016 ◽  
Vol 46 ◽  
pp. 11-17 ◽  
Author(s):  
Yoshiyuki Kobayashi ◽  
Hiroaki Hobara ◽  
Thijs A. Heldoorn ◽  
Makiko Kouchi ◽  
Masaaki Mochimaru
Keyword(s):  
Principal Component Analysis ◽  
Sex Differences ◽  
Principal Component ◽  
Component Analysis ◽  
Gait Pattern ◽  
Age Dependent ◽  
Age Independent

scholarly journals TMIC-34. SENESCENT ASTROCYTE INDUCED INFLAMMATION MAY UNDERLIE SEX DIFFERENCES IN THE AGE-DEPENDENT RISE IN GLIOBLASTOMA INCIDENCE

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi255-vi255
Author(s):  
Gina Rhee ◽  
Lauren Broestl ◽  
Lucia Grandison ◽  
Nicole Warrington ◽  
Najla Kfoury ◽  
...  
Keyword(s):  
Sex Differences ◽  
Inflammatory Cell ◽  
Recipient Mouse ◽  
Biological Mechanisms ◽  
Astrocyte Activation ◽  
Male And Female ◽  
Cell Recruitment ◽  
Age Dependent ◽  
Inflammatory Cell Recruitment ◽  
Secretory Phenotype

Abstract Sex differences in the rates of glioblastoma increase with age. There are likely to be multiple biological mechanisms underlying these sex differences. Here, we focused on the changes that occur with aging in the secretomes of male and female astrocytes to determine whether sex differences in chemokine and cytokine secretion, and inflammatory cell recruitment, could be one of those mechanisms. We focused on glioblastoma (GBM) and the role that senescent astrocytes might play in the age-dependent widening of the gap between male and female GBM cases. We found that the senescence associated secretory phenotype of male and female astrocytes significantly differed, notably in the enrichment of Fractalkine (1.33:1 (F:M)), the primary chemoattractant for microglia, in female compared to male SASP. This was in contrast to the greater abundance of tumorigenic growth factors like bFGF (1.25:1 (M:F)), in the male SASP. Implantation of either male or female senescent astrocytes into the brains of mice resulted in the recruitment of microglia to the injection site. Regardless of the recipient mouse sex, female astrocyte implantation resulted in significantly larger microglial infiltrates (2-fold) and greater astrocyte activation, as compared to the injection of equal numbers of male senescent cells. We propose a model for how sex differences in astrocyte SASP could result in lower rates of GBM with age in females: greater microglial attraction to senescent cells results in their enhanced clearance and consequently a reduction in senescence-associated GBM promotion.

Sex differences in language asymmetry are age-dependent and small: A large-scale, consonant–vowel dichotic listening study with behavioral and fMRI data

Cortex ◽  
2013 ◽  
Vol 49 (7) ◽  
pp. 1910-1921 ◽  
Author(s):  
Marco Hirnstein ◽  
René Westerhausen ◽  
Maria S. Korsnes ◽  
Kenneth Hugdahl
Keyword(s):  
Sex Differences ◽  
Dichotic Listening ◽  
Large Scale ◽  
Fmri Data ◽  
Age Dependent

scholarly journals Sex Differences of Age-Dependent Changes of Insulin Sensitivity in Japanese Nondiabetic Subjects

Diabetes Care ◽  
2005 ◽  
Vol 28 (10) ◽  
pp. 2590a-2591a ◽  
Author(s):  
M. Otsuki ◽  
S. Kasayama ◽  
H. Saito ◽  
M. Mukai ◽  
M. Koga
Keyword(s):  
Sex Differences ◽  
Insulin Sensitivity ◽  
Age Dependent

scholarly journals Age-related DNA methylation changes are sex-specific: a comprehensive assessment

2020 ◽  
Author(s):  
Igor Yusipov ◽  
Maria Giulia Bacalini ◽  
Alena Kalyakulina ◽  
Mikhail Krivonosov ◽  
Chiara Pirazzini ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Sex Differences ◽  
Meta Analysis ◽  
Large Fraction ◽  
Age Related ◽  
Genome Wide ◽  
Epigenetic Age ◽  
Age Dependent ◽  
Males And Females ◽  
Methylation Patterns

AbstractIn humans, females live longer than males but experience a worse longevity, as genome-wide autosomal DNA methylation differences between males and females have been reported. So far, few studies have investigated if DNA methylation is differently affected by aging in males and females. We performed a meta-analysis of 4 large whole blood datasets, comparing 4 aspects of epigenetic age-dependent remodeling between the two sexes: differential methylation, variability, epimutations and entropy. We reported that a large fraction (43%) of sex-associated probes undergoes age-associated DNA methylation changes, and that a limited number of probes shows age-by-sex interaction. We experimentally validated 2 regions mapping in FIGN and PRR4 genes, and showed sex-specific deviations of their methylation patterns in models of decelerated (centenarians) and accelerated (Down syndrome) aging. While we did not find sex differences in the age-associated increase in epimutations and in entropy, we showed that the number of probes showing age-related increase in methylation variability is 15 times higher in males compared to females. Our results can offer new epigenetic tools to study the interaction between aging and sex and can pave the way to the identification of molecular triggers of sex differences in longevity and age-related diseases prevalence.

Sex differences in the sensitivity of CBA mice to convulsions induced by GABA antagonists are age-dependent

1987 ◽  
Vol 91 (2) ◽  
pp. 226-229 ◽  
Author(s):  
Hari Manev ◽  
Danka Peričić ◽  
Suzana Anić-Stojiljković
Keyword(s):  
Sex Differences ◽  
Gaba Antagonists ◽  
Cba Mice ◽  
Age Dependent
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