scholarly journals Dynamic and Responsive Growth Factor Delivery from Electrospun and Hydrogel Tissue Engineering Materials

2017 ◽  
Vol 7 (1) ◽  
pp. 1700836 ◽  
Author(s):  
Kiara F. Bruggeman ◽  
Richard J. Williams ◽  
David R. Nisbet
2016 ◽  
Vol 22 (1) ◽  
pp. 49-58 ◽  
Author(s):  
Jagoda M. Jalowiec ◽  
Matteo D'Este ◽  
Jennifer Jane Bara ◽  
Jessica Denom ◽  
Ursula Menzel ◽  
...  

2017 ◽  
Vol 37 (3) ◽  
Author(s):  
Josephine C. Adams

In a recent publication in Bioscience Reports “Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies”, Brown et al. identified by mass spectrometry and immunoblotting that certain commercial preparations of the small leucine-rich proteoglycans (SLRPs) decorin and biglycan, in fact, contained a mix of several proteoglycans that also included fibromodulin and aggrecan. The preparations were thus not suitable to study specific activities of decorin or biglycan. Decorin and biglycan are widely studied SLRPs that are considered to have highly multi-functional effects on cells. Decorin is of interest as a transforming growth factor-β antagonist and is also finding use in tissue engineering materials. This Commentary discusses Brown et al.’s findings and general issues raised for researchers who work with commercially sourced purified proteoglycans.


RSC Advances ◽  
2018 ◽  
Vol 8 (30) ◽  
pp. 16503-16512 ◽  
Author(s):  
Chun Xu ◽  
Jia Xu ◽  
Lan Xiao ◽  
Zhihao Li ◽  
Yin Xiao ◽  
...  

Microsphere based drug delivery systems show great advantages for tissue engineering.


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