Carbon Dots with Intrinsic Theranostic Properties for Bioimaging, Red-Light-Triggered Photodynamic/Photothermal Simultaneous Therapy In Vitro and In Vivo

2015 ◽  
Vol 5 (6) ◽  
pp. 665-675 ◽  
Author(s):  
Jiechao Ge ◽  
Qingyan Jia ◽  
Weimin Liu ◽  
Minhuan Lan ◽  
Bingjiang Zhou ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Red Light

Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo

2021 ◽  
Author(s):  
Lijuan Liu ◽  
Shengting Zhang ◽  
Xiaodan Zheng ◽  
Hongmei Li ◽  
Qi Chen ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fusobacterium Nucleatum ◽  
Living Cells ◽  
First Time ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Fusobacterium nucleatum has been employed for the first time to synthesize fluorescent carbon dots which could be applied for the determination of Fe3+ ions in living cells and bioimaging in vitro and in vivo with excellent biocompatibility.

scholarly journals Combined In Vitro and In Vivo Approaches to Propose a Putative Adverse Outcome Pathway for Acute Lung Inflammation Induced by Nanoparticles: A Study on Carbon Dots

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 180
Author(s):  
Maud Weiss ◽  
Jiahui Fan ◽  
Mickaël Claudel ◽  
Luc Lebeau ◽  
Françoise Pons ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Lung Inflammation ◽  
Adverse Outcome ◽  
Cellular Responses ◽  
Target Cells ◽  
Inflammasome Activation ◽  
Adverse Outcome Pathway ◽  
Acute Lung Inflammation

With the growth of nanotechnologies, concerns raised regarding the potential adverse effects of nanoparticles (NPs), especially on the respiratory tract. Adverse outcome pathways (AOP) have become recently the subject of intensive studies in order to get a better understanding of the mechanisms of NP toxicity, and hence hopefully predict the health risks associated with NP exposure. Herein, we propose a putative AOP for the lung toxicity of NPs using emerging nanomaterials called carbon dots (CDs), and in vivo and in vitro experimental approaches. We first investigated the effect of a single administration of CDs on mouse airways. We showed that CDs induce an acute lung inflammation and identified airway macrophages as target cells of CDs. Then, we studied the cellular responses induced by CDs in an in vitro model of macrophages. We observed that CDs are internalized by these cells (molecular initial event) and induce a series of key events, including loss of lysosomal integrity and mitochondrial disruption (organelle responses), as well as oxidative stress, inflammasome activation, inflammatory cytokine upregulation and macrophage death (cellular responses). All these effects triggering lung inflammation as tissular response may lead to acute lung injury.

Lysosome-targeted red-fluorescent carbon dots for turn-on detection of permanganate and pH in vivo and in vitro

2021 ◽  
pp. 130774
Author(s):  
Dan Chang ◽  
Zhonghua Zhao ◽  
Jianyang Feng ◽  
Yuye Xin ◽  
Yongxing Yang ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Turn On ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Visible red light enhances physiological anagen entry in vivo and has direct and indirect stimulative effects in vitro

2014 ◽  
Vol 47 (1) ◽  
pp. 50-59 ◽  
Author(s):  
Yi-Shuan Sheen ◽  
Sabrina Mai-Yi Fan ◽  
Chih-Chieh Chan ◽  
Yueh-Feng Wu ◽  
Shiou-Hwa Jee ◽  
...  
Keyword(s):  
Red Light

In situ synthesis of NIR-light emitting carbon dots derived from spinach for bio-imaging applications

2017 ◽  
Vol 5 (35) ◽  
pp. 7328-7334 ◽  
Author(s):  
Liping Li ◽  
Ruiping Zhang ◽  
Chunxiang Lu ◽  
Jinghua Sun ◽  
Lingjie Wang ◽  
...  
Keyword(s):  
Optical Properties ◽  
Carbon Dots ◽  
In Situ Synthesis ◽  
Light Emitting ◽  
Nir Light ◽  
Bio Imaging ◽  
One Step

NIR-light emitting CDs (R-CDs) were prepared using spinach as a precursor by one-step solvothermal treatment. The R-CDs exhibited great optical properties, negligible toxicity, and superior labelling capability both in vitro and in vivo.

Facile synthesis of red-emitting carbon dots from pulp-free lemon juice for bioimaging

2017 ◽  
Vol 5 (26) ◽  
pp. 5272-5277 ◽  
Author(s):  
Hui Ding ◽  
Yuan Ji ◽  
Ji-Shi Wei ◽  
Qing-Yu Gao ◽  
Zi-Yuan Zhou ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Lemon Juice ◽  
Facile Synthesis

A facile method was developed to produce efficient red-emitting carbon dots from pulp-free lemon juice for bioimaging both in vitro and in vivo.

Low temperature synthesis of phosphorous and nitrogen co-doped yellow fluorescent carbon dots for sensing and bioimaging

2015 ◽  
Vol 3 (33) ◽  
pp. 6813-6819 ◽  
Author(s):  
Xiaojuan Gong ◽  
Wenjing Lu ◽  
Yang Liu ◽  
Zengbo Li ◽  
Shaomin Shuang ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Ph Sensing ◽  
Low Temperature Synthesis ◽  
Low Toxicity ◽  
Doped Carbon Dots ◽  
Fluorescent Carbon Dots ◽  
Co Doped ◽  
High Output

A simple and high-output strategy for the fabrication of yellow fluorescent phosphorous and nitrogen co-doped carbon dots (P,N-CDs) is developed. P,N-CDs possess distinctive photoluminescence properties, low toxicity, and biocompatible. P,N-CDs are potentially useful for versatile applications such as pH sensing, in vitro and in vivo imaging.

Fluorescent carbon dots from antineoplastic drug etoposide for bioimaging in vitro and in vivo

2017 ◽  
Vol 5 (38) ◽  
pp. 7796-7800 ◽  
Author(s):  
Bin Wu ◽  
Rongrong Zhu ◽  
Mei Wang ◽  
Peng Liang ◽  
Yechang Qian ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Antineoplastic Drug ◽  
Step Method ◽  
One Step ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Carbon dots for bioimaging in vitro and in vivo were synthesized from the antineoplastic drug etoposide by a one-step method.

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