Mild Methodology for the Versatile Chemical Modification of Polylactide Surfaces: Original Combination of Anionic and Click Chemistry for Biomedical Applications

2011 ◽  
Vol 21 (17) ◽  
pp. 3321-3330 ◽  
Author(s):  
Sarah El Habnouni ◽  
Vincent Darcos ◽  
Xavier Garric ◽  
Jean-Philippe Lavigne ◽  
Benjamin Nottelet ◽  
...  
Keyword(s):  
Chemical Modification ◽  
Click Chemistry ◽  
Biomedical Applications

Chemical modification of enveloped viruses for biomedical applications

2018 ◽  
Vol 10 (11) ◽  
pp. 666-679 ◽  
Author(s):  
Pahweenvaj Ratnatilaka Na Bhuket ◽  
Jittima Amie Luckanagul ◽  
Pornchai Rojsitthisak ◽  
Qian Wang
Keyword(s):  
Drug Delivery ◽  
Chemical Modification ◽  
Biomedical Applications ◽  
Vaccine Development ◽  
Enveloped Viruses ◽  
Bio Imaging

Chemistry enables scientists to use enveloped viruses in several biomedical applications including bio-imaging, drug delivery and vaccine development.

Dendrimer Synthesis and Functionalization by Click Chemistry for Biomedical Applications

2009 ◽  
pp. 177-193 ◽  
Author(s):  
Daniel Q. McNerny ◽  
Douglas G. Mullen ◽  
Istvan J. Majoros ◽  
Mark M. Banaszak Holl ◽  
James R. Baker
Keyword(s):  
Click Chemistry ◽  
Biomedical Applications

scholarly journals "Click" chemistry as a tool to create novel biomaterials: a short review

2017 ◽  
Vol 1 (1) ◽  
pp. 22-34
Author(s):  
Mariana Barbosa ◽  
Cristina Martins ◽  
Paula Gomes
Keyword(s):  
Click Chemistry ◽  
Biomedical Applications ◽  
Recent Literature ◽  
Click Reaction ◽  
Cycloaddition Reaction ◽  
Polymeric Materials ◽  
Short Review ◽  
Dipolar Cycloaddition ◽  
Functionalization Of Polymers ◽  
Grafting Modification

In recent years, there has been a growing demand for novel strategies for biomedical applications. Chitosan is a typical cationic amino-containing polysaccharide that has been widely used due to its unique properties. The grafting modification of chitosan has been explored as an interesting method to develop multifunctional novel chitosan hybrid materials for drug delivery, tissue engineering, and other biomedical applications. Recently, “click” chemistry has been introduced into the synthesis of polymeric materials with well-defined and complex chain architectures. The Huisgen’s 1,3-dipolar cycloaddition reaction between alkynes and azides yielding triazoles is the principal example of a “click” reaction. Bioconjugation, surface modification, and orthogonal functionalization of polymers were successfully performed through this chemoselective reaction. In recent literature interest has been shown in this cycloaddition for the modification of polysaccharides, however, only a few chitosan graft copolymers have been synthesized by this technique.

scholarly journals Mild Covalent Functionalization of Transition Metal Dichalcogenides with Maleimides: A “Click” Reaction for TMDCs

2018 ◽  
Author(s):  
Mariano Vera-Hidalgo ◽  
Emerson Giovanelli ◽  
Cristina Navío ◽  
Emilio Pérez
Keyword(s):  
Transition Metal ◽  
Chemical Modification ◽  
Biomedical Applications ◽  
Click Reaction ◽  
Transition Metal Dichalcogenides ◽  
Polymer Chemistry ◽  
Covalent Functionalization ◽  
Click Reactions ◽  
Mild Conditions ◽  
Metal Dichalcogenides

The physical properties of ultrathin transition metal dichalcogenides (2D-TMDCs) make them promising candidates as active nanomaterials for catalysis, optoelectronics, and biomedical applications. Chemical modification of TMDCs is expected to be key in modifying/adding new functions that will help make such promise a reality. We present a mild method for the modification of the basal planes of 2H-MoS<sub>2</sub> and WS<sub>2</sub>. We exploit the soft nucleophilicity of sulfur to react it with maleimide derivatives, achieving covalent functionalization of 2H-TMDCs under very mild conditions. Extensive characterization proves that the reaction occurs through Michael addition. Our results adapt one of the most popular “click” reactions in polymer chemistry and biochemistry to obtain a powerful tool for the chemical manipulation of TMDCs.

Ionic liquids in the processing and chemical modification of chitin and chitosan for biomedical applications

2017 ◽  
Vol 19 (5) ◽  
pp. 1208-1220 ◽  
Author(s):  
Simone S. Silva ◽  
João F. Mano ◽  
Rui L. Reis
Keyword(s):  
Ionic Liquids ◽  
Chemical Modification ◽  
Biomedical Applications ◽  
Chitin And Chitosan

Ionic liquids (ILs) have huge potential to provide new ways for the sustainable processing of chitin and chitosan to a variety of matrices for biomedical applications

The study of the pseudo-polyrotaxane architecture as a route for mild surface functionalization by click chemistry of poly(ε-caprolactone)-based electrospun fibers

2017 ◽  
Vol 5 (11) ◽  
pp. 2181-2189 ◽  
Author(s):  
M. Oster ◽  
G. Schlatter ◽  
S. Gallet ◽  
R. Baati ◽  
E. Pollet ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Surface Functionalization ◽  
Biomedical Applications ◽  
Copper Catalysts ◽  
Electrospun Fibers

PCL fibers with pseudopolyrotaxanes at their surface are functionalized with bicyclononyne clickable groups making possible an easy bioconjugation in water and without copper catalysts for biomedical applications.

Synthesis of an MUC1 Glycopeptide Dendrimer Based on β-Cyclodextrin by Click Chemistry

Synlett ◽  
2017 ◽  
Vol 28 (15) ◽  
pp. 1961-1965 ◽  
Author(s):  
Yan-Mei Li ◽  
Pu-Guang Chen ◽  
Zhi-Hua Huang ◽  
Zhan-Yi Sun ◽  
Qian-Qian Li ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Efficient Method ◽  
Biomedical Applications ◽  
Catalyst System

Glycopeptide dendrimers are attractive candidates for biomedical applications. Here, an efficient method for preparing multivalent MUC1 glycopeptide dendrimers based on β-cyclodextrin is described. By using copper(I) bromide and thioanisole as a catalyst system, precisely defined heptavalent conjugates were efficiently obtained. Using this heptavalent glycopeptide dendrimer, we observed multivalent effects in recognition and association processes in antibody and epitope interactions, which might have biomedical applications.

scholarly journals Synergistically complexation of phenol functionalized polymer induced in-situ microfiber formation for 3D printing of marine-based hydrogel

2022 ◽  
Author(s):  
Hafez Jafari ◽  
Christine Delporte ◽  
Katrien V. Bernaerts ◽  
Houman Alimoradi ◽  
Lei Nie ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
3D Printing ◽  
Chemical Modification ◽  
Biomedical Applications ◽  
Safe Approach

The design of 3D printable bio-based hydrogels with enhanced mechanical properties and minimal chemical modification can open new opportunities in the field of biomedical applications. A facile and safe approach...

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