squalene synthetase Latest Research Papers

ChemInform Abstract: Squalene Synthetase Inhibitors: Synthesis of Sulfonium Ion Mimics of the Carbocationic Intermediates.

ChemInform ◽

10.1002/chin.199144271 ◽

2010 ◽

Vol 22 (44) ◽

pp. no-no

Author(s):

A. C. OEHLSCHLAGER ◽

S. M. SINGH ◽

S. SHARMA

Keyword(s):

Squalene Synthetase

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ChemInform Abstract: Isoprenyl Phosphinylformates: New Inhibitors of Squalene Synthetase.

ChemInform ◽

10.1002/chin.199146271 ◽

2010 ◽

Vol 22 (46) ◽

pp. no-no

Author(s):

S. A. BILLER ◽

C. FORSTER ◽

E. M. GORDON ◽

T. HARRITY ◽

L. C. RICH ◽

...

Keyword(s):

Squalene Synthetase

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ChemInform Abstract: Synthesis and Squalene Synthetase Inhibitory Activity of Tripotassium 1-Methyl-1-((N-benzyl-N-farnesyl)aminoethylphosphinato) ethylphosphonate (I) as a Tethered Analog of N-Benzyl-N-farnesylamine - Inorganic Pyrophosphate Ion Pair.

ChemInform ◽

10.1002/chin.199423194 ◽

2010 ◽

Vol 25 (23) ◽

pp. no-no

Author(s):

M. PRASHAD

Keyword(s):

Inhibitory Activity ◽

Ion Pair ◽

Inorganic Pyrophosphate ◽

Squalene Synthetase

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Enzymatic resolution of benzothiazepine for the preparation of squalene synthetase inhibitors

Tetrahedron Asymmetry ◽

10.1016/s0957-4166(00)00458-4 ◽

2000 ◽

Vol 11 (22) ◽

pp. 4447-4450 ◽

Cited By ~ 16

Author(s):

Xiaojing Yang ◽

Leanne Buzon ◽

Ernie Hamanaka ◽

Kevin K.-C. Liu

Keyword(s):

Enzymatic Resolution ◽

Squalene Synthetase

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HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)33336-8 ◽

1999 ◽

Vol 40 (1) ◽

pp. 24-38 ◽

Cited By ~ 4

Author(s):

Stephen F. Petras ◽

Saralyn Lindsey ◽

H. James Harwood

Keyword(s):

Hmg Coa Reductase ◽

Coa Reductase ◽

Squalene Synthetase

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2.P.40 Discovery of the squalene synthetase inhibitor CP-340,868

Atherosclerosis ◽

10.1016/s0021-9150(97)88678-9 ◽

1997 ◽

Vol 134 (1-2) ◽

pp. 125 ◽

Cited By ~ 1

Author(s):

C.M. Hayward ◽

E.S. Hamanaka ◽

R.J. Aiello ◽

H.J. Harwood ◽

C.E. Aldinger ◽

...

Keyword(s):

Synthetase Inhibitor ◽

Squalene Synthetase

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2.P.28 Preclinical drug metabolism studies in rat, mouse, dog and monkey with allometric scaling for CP-340,868, a novel squalene synthetase inhibitor

Atherosclerosis ◽

10.1016/s0021-9150(97)88665-0 ◽

1997 ◽

Vol 134 (1-2) ◽

pp. 122

Author(s):

W.W. Day ◽

M.C. Allen ◽

E.S. Hamanaka ◽

R.J. Aiello ◽

J.T. Mayne ◽

...

Keyword(s):

Drug Metabolism ◽

Allometric Scaling ◽

Synthetase Inhibitor ◽

Squalene Synthetase

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Squalene synthetase inhibitors

Drug Discovery Today ◽

10.1016/s1359-6446(97)83298-9 ◽

1997 ◽

Vol 2 (2) ◽

pp. 80

Keyword(s):

Squalene Synthetase

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Molecular cloning, in vitro expression and characterization of a plant squalene synthetase cDNA

Plant Molecular Biology ◽

10.1007/bf00019548 ◽

1996 ◽

Vol 30 (6) ◽

pp. 1139-1151 ◽

Cited By ~ 32

Author(s):

Kathleen M. Hanley ◽

Olivier Nicolas ◽

Timothy B. Donaldson ◽

Constance Smith-Monroy ◽

Gordon W. Robinson ◽

...

Keyword(s):

Molecular Cloning ◽

In Vitro Expression ◽

Squalene Synthetase

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Inhibition of Mammalian Squalene Synthetase Activity by Zaragozic Acid A Is a Result of Competitive Inhibition Followed by Mechanism-based Irreversible Inactivation

Journal of Biological Chemistry ◽

10.1074/jbc.270.16.9083 ◽

1995 ◽

Vol 270 (16) ◽

pp. 9083-9096 ◽

Cited By ~ 30

Author(s):

Saralyn Lindsey ◽

H. James Harwood

Keyword(s):

Competitive Inhibition ◽

Synthetase Activity ◽

Zaragozic Acid ◽

Squalene Synthetase

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squalene synthetase
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H-INDEX

ChemInform Abstract: Squalene Synthetase Inhibitors: Synthesis of Sulfonium Ion Mimics of the Carbocationic Intermediates.

ChemInform Abstract: Isoprenyl Phosphinylformates: New Inhibitors of Squalene Synthetase.

ChemInform Abstract: Synthesis and Squalene Synthetase Inhibitory Activity of Tripotassium 1-Methyl-1-((N-benzyl-N-farnesyl)aminoethylphosphinato) ethylphosphonate (I) as a Tethered Analog of N-Benzyl-N-farnesylamine - Inorganic Pyrophosphate Ion Pair.

Enzymatic resolution of benzothiazepine for the preparation of squalene synthetase inhibitors

HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells

2.P.40 Discovery of the squalene synthetase inhibitor CP-340,868

2.P.28 Preclinical drug metabolism studies in rat, mouse, dog and monkey with allometric scaling for CP-340,868, a novel squalene synthetase inhibitor

Squalene synthetase inhibitors

Molecular cloning, in vitro expression and characterization of a plant squalene synthetase cDNA

Inhibition of Mammalian Squalene Synthetase Activity by Zaragozic Acid A Is a Result of Competitive Inhibition Followed by Mechanism-based Irreversible Inactivation

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squalene synthetaseRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

ChemInform Abstract: Squalene Synthetase Inhibitors: Synthesis of Sulfonium Ion Mimics of the Carbocationic Intermediates.

ChemInform Abstract: Isoprenyl Phosphinylformates: New Inhibitors of Squalene Synthetase.

ChemInform Abstract: Synthesis and Squalene Synthetase Inhibitory Activity of Tripotassium 1-Methyl-1-((N-benzyl-N-farnesyl)aminoethylphosphinato) ethylphosphonate (I) as a Tethered Analog of N-Benzyl-N-farnesylamine - Inorganic Pyrophosphate Ion Pair.

Enzymatic resolution of benzothiazepine for the preparation of squalene synthetase inhibitors

HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells

2.P.40 Discovery of the squalene synthetase inhibitor CP-340,868

2.P.28 Preclinical drug metabolism studies in rat, mouse, dog and monkey with allometric scaling for CP-340,868, a novel squalene synthetase inhibitor

Squalene synthetase inhibitors

Molecular cloning, in vitro expression and characterization of a plant squalene synthetase cDNA

Inhibition of Mammalian Squalene Synthetase Activity by Zaragozic Acid A Is a Result of Competitive Inhibition Followed by Mechanism-based Irreversible Inactivation

squalene synthetase
Recently Published Documents