spontaneous neoplasm
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scholarly journals Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study

2020 ◽  
Vol 2 (4) ◽  
pp. 219-222
Author(s):  
Eleonora Duregon ◽  
◽  
Camila Vieira Ligo Teixeira ◽  
Rafael de Cabo
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Clinical Finding ◽  
Hind Limb ◽  
Histological Analysis ◽  
Tumor Burden ◽  
Limb Weakness ◽  
Intervertebral Disks ◽  
Spontaneous Neoplasm

A female UM-HET3 mouse from the Study of Longitudinal Aging in Mice (SLAM) was euthanized at 164 weeks of age due to hind limb weakness. Necropsy and histological analysis revealed that the most probable cause of the clinical finding was the compression of the thoracolumbar segment of the spinal cord by herniated intervertebral disks. In addition, a spontaneous chordoma was incidentally found in the coccygeal bones. Given the rarity of this type of tumor, bio-clinical annotations acquired throughout lifespan, detailed histopathological assessment, and comparative clinical-pathological correlations for this mouse are presented and discussed. Keywords: Geropathology, geroscience, study of longitudinal aging in mice (SLAM), spontaneous neoplasm, tumor burden, chordoma

scholarly journals Intrauterine Choriocarcinoma in a Rhesus Monkey

1969 ◽  
Vol 6 (4) ◽  
pp. 378-384 ◽  
Author(s):  
J. R. gLindsey ◽  
L. R. Wharton ◽  
J. D. Woodruff ◽  
H. J. Baker
Keyword(s):  
Rhesus Monkey ◽  
Pulmonary Metastasis ◽  
Reproductive Organs ◽  
Spontaneous Neoplasm ◽  
Female Reproductive Organs

A spontaneous neoplasm (the fourth reported from the female reproductive organs of the rhesus monkey) is described-an intrauterine choriocarcinoma with massive pulmonary metastasis.

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