International Patent Survey of Products and Processes Concerning Homeopathy

Background Homeopathy is a complementary medicine characterized by the use of diluted and potentized medicines. Innovations in this area are constantly being proposed in the relevant literature, such as scientific articles and patents. The objective of this study was to carry out a patent survey of homeopathic products and processes. Methods A free and international patent database, Espacenet, was used. The search was carried out using the keyword homeop*, with two approaches: (1) no date restrictions for the search and (2) a date limit for the publication years 2008 to 2018. The patents from the limited period were organized as depositor countries, ownerships and groups, including homeopathic formulations, equipment, packaging, production procedures, and analytical methods. Results Without date restriction, 601 patents were identified in the survey. Of these, 174 were related to homeopathy and published in the period 2008 to 2018. Technologies come mainly from the following countries: United States (55 patents), Russia (24), Germany (15), France (13), India (12), Ukraine (11), Brazil (6), and China (6). Among the ownerships, 69% of patent applications were by independent depositors, 23% by companies, 7.5% by universities, and 0.5% by company/university partnerships. New formulations represented 75.9% of technologies, whilst the others comprised 14.3% for equipment, 3.8% for drugs packaging, 3.8% for production procedures, and 2.2% for analytical methods. Conclusions The present review helps visualize the homeopathy-related patents published in recent years, as well as the main countries and researchers investing in the field of homeopathy.

Anti-Inflammatory Activity of the Compositae Family and Its Therapeutic Potential

Compositae is the largest family of flowering plants, with more than 1600 genera and 22 000 species. It has many economic uses in foods, cosmetics, and pharmaceutics. The literature reports its numerous medicinal benefits and recognized anti-inflammatory activity. Thus, this study evaluated the technological trends of anti-inflammatory activity of Compositae, based on the survey of scientific databases, articles, and patents, as well as the website of the Brazilian National Health Regulatory Agency (ANVISA), which is responsible for registering and controlling of healthcare and cosmetic products in the Brazil. The survey was conducted between 2008 and 2018, in the databases Science Direct, Lilacs, PubMed, and Web of Science (main collection), as well as the SciELO Citation Index. The patent survey was carried out on the basis of the Derwent Innovations Index, an important source for worldwide patent consultation, which covers 20 y of registered patents. Despite the numerous studies involving species of the Compositae family in different models of anti-inflammatory activity, there are few records of patents or products on the market from these species for that purpose. Some species have a traditional use and are present even in the Phytotherapic Summary of the Brazilian Pharmacopeia. This review confirms the therapeutic potential of Compositae for the development of anti-inflammatory drugs and reinforces the need to develop competencies and reduce technological bottlenecks to promote research and innovation in biodiversity products.

Patent Analysis and Structural Synthesis of Epicyclic Gear Trains Used in Automatic Transmissions

A patent survey is conducted to investigate the application status of epicyclic gear trains (EGTs) used in automatic transmissions (ATs). In this regard, 673 AT patents are investigated firstly, and 274 different EGTs are obtained after the patent processing. EGTs are presented by corresponding double bicolor graphs (DBGs) and they are sorted into 13 groups in accordance with the degree of freedom (DOF) of DBGs and the degree of hollow vertices. Then, structural characteristics of obtained EGTs, which are used to detect whether the EGTs obtained in the future can be used in ATs, are analyzed and summarized. Finally, a new approach is proposed to obtain new configurations of the EGTs with one main shaft based on the transformation relation between DBG and the basic graph. Several examples are presented to illustrate the validity of the proposed approach.

THE SELF-REPORTED PATENT QUALITY OF CHINESE FIRMS: MOTIVATION SOURCE AND TECHNOLOGY ACCUMULATION EFFECTS ANALYSIS

Enhanced innovation capacity has become imperative to China’s growth and development. Patent quantity and quality indicators are benchmark measures of innovative capacity. This paper utilizes data from the 2013 Chinese Patent Survey to explore self-evaluated firm-level patent quality in China. Focus is placed on the effects of technological accumulation and also patent motivation on four multi-dimensional self-evaluation indices: technical quality, writing quality, right stability and market value. The results: (i) verify the proposal that in high patent intensity industries “strategic patent behavior will reduce patent quality”; (ii) suggest that reducing administrative-driven patent behaviors could improve patent quality and (iii) find patent structure but not quantity to be positively correlated with patent quality. This serves to enrich understanding of China’s patent system and the one-dimensional “inventive step” analysis deriving from analyses of European Patent Survey data.