zanthoxylum heitzii
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Author(s):  
Bertin Mikolo ◽  

The objective of this study was to evaluate crude extracts of leaves, bark and seeds of the plant Zanthoxylum heitzii using hexane, ethyl acetate, ethanol, water/ethanol and water solvents, and to evaluate the extracts for repellence to the malaria mosquito, Anopheles gambiae.


2017 ◽  
Vol 2017 ◽  
pp. 1-11
Author(s):  
Jacques Joël Essogo ◽  
Bruno Moukette Moukette ◽  
Francine Nzufo Tankeu ◽  
Pauline Nanfack ◽  
Constant Anatole Pieme

Ferric nitrilotriacetate (Fe-NTA) is a highly reactive compound used to induce degenerative disorders through oxidative stress (OS). Zanthoxylum heitzii (Z. heitzii) is a spice used as a medicinal plant to treat a variety of illnesses. This study investigated the ability of extracts from the leaves, fruits, roots, and barks of Z. Heitzii to inhibit Fe-NTA mediated oxidative damage in rats. The supernatant of rat liver homogenates was pretreated with the extracts for one hour before the induction of oxidative damage using a solution of Fe-NTA (400 mM). The activities of superoxide dismutase (SOD), catalase, and peroxidases were measured together with the marker of lipid peroxidation and the level of glutathione. The pretreated groups showed a significant increase in the activity of SOD, catalase, and peroxidases. The methanolic extract from the leaves of Z. heitzii (36.78 ± 3.30) and aqueous extract from the fruits (37.01 ± 2.52) showed the highest activities of SOD in the liver. The lowest concentration of MDA was found in the liver, and the glutathione was greater in the brain. Conclusively, these results suggest that Z. heitzii might be a chemoprotector which may be used in for prevention of distinct types of diseases induced by oxidative stress.


2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Christopher Dean Goodman ◽  
Ingvild Austarheim ◽  
Vanessa Mollard ◽  
Bertin Mikolo ◽  
Karl Egil Malterud ◽  
...  

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Christopher Dean Goodman ◽  
Ingvild Austarheim ◽  
Vanessa Mollard ◽  
Bertin Mikolo ◽  
Karl Egil Malterud ◽  
...  

Fitoterapia ◽  
2016 ◽  
Vol 109 ◽  
pp. 196-200 ◽  
Author(s):  
Helle Wangensteen ◽  
Giang Thanh Thi Ho ◽  
Margey Tadesse ◽  
Christopher O. Miles ◽  
Nastaran Moussavi ◽  
...  

2015 ◽  
Vol 13 (5) ◽  
pp. 326-335 ◽  
Author(s):  
Fidèle Ntchapda ◽  
Maguirgue Kakesse ◽  
Michel Archange Tagne Fokam ◽  
Olivier Mbouemboue Pancha ◽  
Djedouboum Abakar ◽  
...  

2015 ◽  
Vol 8 (5) ◽  
pp. 359-365 ◽  
Author(s):  
Fidele Ntchapda ◽  
Kakesse Maguirgue ◽  
Hamadjida Adjia ◽  
Paul Faustin Seke Etet ◽  
Théophile Dimo

Molecules ◽  
2014 ◽  
Vol 19 (12) ◽  
pp. 21276-21290 ◽  
Author(s):  
Hans Overgaard ◽  
Patcharawan Sirisopa ◽  
Bertin Mikolo ◽  
Karl Malterud ◽  
Helle Wangensteen ◽  
...  

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