Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop

People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated risk of multiple age-associated comorbidities. To discuss current knowledge, research gaps, and priorities in aging and age-related comorbidities in treated HIV infection, the NIH program staff organized a workshop held in Bethesda, Maryland in September 2019. This review article describes highlights of discussions led by the Pathogenesis/Basic Science Research working group that focused on three high priority topics: immunopathogenesis; the microbiome/virome; and aging and senescence. We summarize knowledge in these fields and describe key questions for research on the pathogenesis of aging and age-related comorbidities in PWH. Understanding the drivers and mechanisms underlying accentuated biological aging is a high priority that will help identify potential therapeutic targets to improve healthspan in older PWH.

A mikroadatok felhasználása webarchiválási környezetben

Ebben a rövid tanulmányban először rövid áttekintést szeretnék nyújtani a mikroadatokkal ellátott szemantikus jelölőkről s azok általános könyvtári felhasználásáról. A továbbiakban néhány a webarchiválást érintő kihívást említek meg az archivált tartalom megjelenítése, a kutatástámogatás és a hosszútávú digitális megőrzés témaköreihez kapcsolódva. A tanulmány fő célja annak vizsgálata, hogy a mikroadatok felhasználása miként tud segíteni e kihívások kezelésében. Fontosnak tartom kiemelni az International Internet Preservation Consortium (IIPC) Research Working Group tevékenységét, mely nemzetközi értelemben is segíthet összehangolni az érintett kutatási és gyakorlati felhasználási tevékenységeket.

Home Practice: Irish women, Diaspora and Somatic Principles of Hosting

<span>Dr. Emma Meehan is a Research Fellow at Coventry University’s Centre for Dance Research. She received her BA and PhD from the Drama Department, Trinity College, Dublin, where she taught part-time on the BA and MA programmes. She also worked as the administrator for the Arts Technology Research Lab at Trinity College to support the Digital Arts and Humanities Doctoral Programme. Her doctoral research focused on the work of Irish choreographer Joan Davis, who combines dance and somatic practices in creating interactive, site-specific performances. Emma is associate editor for Journal of Dance and Somatic Practices, and was co-convenor of the Performance as Research Working Group at the International Federation for Theatre Research from 2013-2017.</span>

The Investigation of Homicide

This special issue of Homicide Studies devotes attention to the how of homicide investigation. Much like the Homicide Research Working Group itself, this issue calls attention to the contributions of both practical and academic homicide experts. We were looking for manuscripts that examined or extended the various facets of investigating homicide. The processes and practices of law enforcement agencies, prosecutors, and investigators greatly affect case resolution. How these entities interact as well as engage with members of the community go far in determining case success and views of efficacy.

Barriers and opportunities related to extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest in Canada: A report from the first meeting of the Canadian ECPR Research Working Group

For a French translation of the executive summary, please see the Supplementary Material at DOI: 10.1017/cem.2017.429