capsaicin analogues
Recently Published Documents


TOTAL DOCUMENTS

21
(FIVE YEARS 1)

H-INDEX

11
(FIVE YEARS 0)

2021 ◽  
Vol 64 (3) ◽  
pp. 1346-1361
Author(s):  
Stephen D. Richbart ◽  
Jamie R. Friedman ◽  
Kathleen C. Brown ◽  
Rama S. Gadepalli ◽  
Sarah L. Miles ◽  
...  

2020 ◽  
Vol 25 (1) ◽  
pp. 94-103
Author(s):  
Tania Diaz-Vidal ◽  
Luis Carlos Rosales-Rivera ◽  
Juan C. Mateos-Díaz ◽  
Jorge A. Rodríguez

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 915 ◽  
Author(s):  
Erika Cione ◽  
Pierluigi Plastina ◽  
Attilio Pingitore ◽  
Mariarita Perri ◽  
Maria Cristina Caroleo ◽  
...  

In this study, two capsaicin analogues, N-eicosapentaenoyl vanillylamine (EPVA) and N-docosahexaenoyl vanillylamine (DHVA), were enzymatically synthesized from their corresponding n-3 long chain polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both dietary relevant components. The compounds significantly reduced the production of some lipopolysaccharide (LPS)-induced inflammatory mediators, including nitric oxide (NO), macrophage-inflammatory protein-3α (CCL20) and monocyte chemoattractant protein-1 (MCP-1 or CCL2), by RAW264.7 macrophages. Next to this, only EPVA increased insulin secretion by pancreatic INS-1 832/13 β-cells, while raising intracellular Ca2+ and ATP concentrations. This suggests that the stimulation of insulin release occurs through an increase in the intracellular ATP/ADP ratio in the first phase, while is calcium-mediated in the second phase. Although it is not yet known whether EPVA is endogenously produced, its potential therapeutic value for diabetes treatment merits further investigation.


2015 ◽  
Vol 16 (S8) ◽  
Author(s):  
Javier Cáceres ◽  
Romina Sepúlveda ◽  
Camila Navas ◽  
Ramón Latorre ◽  
Fernando González-Nilo
Keyword(s):  

2014 ◽  
Vol 347 (12) ◽  
pp. 885-895 ◽  
Author(s):  
Mariana C. F. C. B. Damião ◽  
Kerly F. M. Pasqualoto ◽  
Adilson K. Ferreira ◽  
Sarah F. Teixeira ◽  
Ricardo A. Azevedo ◽  
...  

2011 ◽  
Vol 55 (3) ◽  
pp. 435-442 ◽  
Author(s):  
BiXian Peng ◽  
JunLian Wang ◽  
ZhengHong Peng ◽  
ShengZe Zhou ◽  
FengQi Wang ◽  
...  
Keyword(s):  

ChemInform ◽  
2010 ◽  
Vol 27 (32) ◽  
pp. no-no
Author(s):  
K. KOBATA ◽  
K. YOSHIKAWA ◽  
M. KOHASHI ◽  
T. WATANABE

Sign in / Sign up

Export Citation Format

Share Document