scholarly journals A Review of Selected Factors of Salivary Gland Tumour Formation and Malignant Transformation

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Pawel Sowa ◽  
Karolina Goroszkiewicz ◽  
Joanna Szydelko ◽  
Joanna Chechlinska ◽  
Katarzyna Pluta ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Malignant Transformation ◽  
Tumour Growth ◽  
Cell Cycle Regulators ◽  
Salivary Gland Tumours ◽  
Complex Processes ◽  
Tumour Formation ◽  
Benign Tumours ◽  
Benign Salivary Gland Tumours ◽  
Gland Tumour

Salivary gland tumours represent about 6% of head and neck neoplasms and about 0.5% of all malignancies in humans. Tumour growth and malignant transformation are complex processes involving various actions of molecules. Furthermore, some malignant salivary gland tumours are deemed to be caused by dedifferentiation or malignant transformation of benign tumours. The mechanisms of this transformation depend on a variety of different elements, such as cell cycle regulators, oncogenes, proteins, angiogenesis factors, and adipocytokines. The authors used PubMed, Medline, and Google websites to find and review the most significant papers related to malignant transformation in benign salivary gland tumours.

Palatal pleomorphic adenoma in a child

1995 ◽  
Vol 109 (4) ◽  
pp. 343-345 ◽  
Author(s):  
A. Noghreyan ◽  
A. Gatot ◽  
E. Maor ◽  
D. M. Fliss
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumours ◽  
A Minor ◽  
Benign Salivary Gland Tumours

AbstractBenign salivary gland tumours in childhood are rare. We present a case of a pleomorphic adenoma arising in a minor salivary gland within the hard palate, review the literature and discuss the diagnostic and therapeutic features of the condition.

scholarly journals A clinical study of the incidence of salivary gland tumors in a tertiary care teaching hospital

2019 ◽  
Vol 6 (6) ◽  
pp. 2110
Author(s):  
Sathish Babu N. ◽  
Naveen H. Mahadev ◽  
Kumar G. V.
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Critical Role ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Salivary Gland Tumour ◽  
Major Salivary Gland ◽  
Salivary Gland Tumours ◽  
Gland Tumour

Background: The salivary gland system of the upper aero digestive tract plays a critical role in the functions of digestion, respiration, communication, and overall homeostasis. The Salivary gland swellings can be broadly classified into inflammatory, non-inflammatory and neoplastic swellings like calculi, benign tumours such has pleomorphic adenoma, oncocytoma, Warthin's tumour, malignant tumors which include-adenocarcinoma, adenoid cystic carcinoma, undifferentiated carcinoma.Methods: The present cross-sectional study was conducted at the Department of general surgery, Sri Siddhartha Medical College over a period of 2 years from August 2016 to July 2018.  All major salivary gland neoplastic swellings confirmed by FNAC were included in this study.Results: In our study 23 patients had major salivary gland tumours out of that 19 patients had parotid and 4 had submandibular major salivary gland tumour. In our study out 23 cases of salivary tumours 19 cases were benign and 4 cases were malignant, out of 19 cases of parotid tumours, 15 (78.94%) cases were seen in superficial lobe and 4 (21.06%) were in deep lobe, out of 23 salivary gland tumours, 19 (82.6%) cases were pleomorphic adenoma 3(13.05%) cases were mucoepidermoid carcinoma and one case (4.35%) was acinic cell carcinoma.Conclusions: Parotid gland was the most common site of origin of both benign and malignant tumours, Pleomorphic adenoma was the most common benign salivary gland tumour and mucoepidermoid carcinoma was the most frequent malignant neoplasm.

scholarly journals SALIVARY GLAND TUMOURS;

2017 ◽  
Vol 24 (09) ◽  
pp. 1327-1330
Author(s):  
Arifullah - ◽  
Irfan Ul Islam Nasir ◽  
Syed Zafar Hassan ◽  
Ghulam Muhammad
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumours ◽  
Surgical Department ◽  
Adenoid Cystic ◽  
Pleomorphic Adenomas ◽  
Warthin’S Tumour ◽  
Benign Tumours ◽  
Common Benign Tumour

Objectives: The objective of the study was to find the frequency of salivarygland tumours. Study Design: A descriptive study. Period: 1st Jan 2008 to 31st Dec 2010 (of 3years duration). Setting: ENT department Khyber Teaching Hospital and Surgical departmentHayatabad Medical Complex, Peshawar. Material and methods: Total number of 108 patientshaving salivary gland tumours enrolled from admitted patients in ENT department KhyberTeaching Hospital and Surgical department Hayatabad Medical Complex Peshawar. Thestudy was designed to find the frequency of salivary gland tumours. Results: In our studymost of the patients were having benign tumours (80.6%) with malignant counterpart in about19.4%. Overall the most common tumour was pleomorphic adenoma about 71.3% followed byMucoepidermoid 6.5%, adenoid cystic carcinoma 4.6% and Warthin’s tumour 4.6%. The mostcommonly involved salivary gland is parotid gland about 78.7% (85/108) with pleomorphicadenoma being the most common benign tumour and Mucoepidermoid the malignant variety.In submandibular gland/ sublingual glands the most common was pleomorphic adenomaand in minor salivary gland majority were malignant. Conclusion: Most of the salivary glandtumours are benign with majority of them are pleomorphic adenomas and parotid gland is themost common involved salivary gland.

scholarly journals Salivary gland tumours: a hospital-based study on demographic and incidence pattern, histopathological types and treatment strategy

2020 ◽  
Vol 6 (12) ◽  
pp. 2218
Author(s):  
M. K. Mili ◽  
Hirak Jyoti Das ◽  
Asha Saikia ◽  
N. J. Saikia ◽  
J. Phookan ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Treatment Strategy ◽  
Tertiary Care ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumour ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Gland Tumour

<p><strong>Background: </strong>Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.</p><p><strong>Methods: </strong>Hospital based cross sectional study was done in a tertiary care centre during a period of 1 year, which included 21 patients (10 men and 11 women). Patients were analysed according to age, gender, food habits, histopathological type and site of the tumour and treatment strategy.</p><p><strong>Results: </strong>All the cases were from upper Assam province sharing a particular demographic pattern between 19-65 years. Peak incidence in males was fourth decade and females was third decade. Male female ratio was 0.9:1. Out of 21 cases, 14 were parotid gland tumours, 6 submandibular gland tumours and 1 minor salivary gland tumour. Most of the tumours were benign (16) and 5 were malignant.</p><p><strong>Conclusions: </strong>Two patients were of age 19 years which is conflicting the normal national incidence. All cases belonged to lower economic strata with decreased intake of beta carotene enriched food items. The most common site is parotid gland and most common tumour is pleomorphic adenoma which is in accordance to other studies. Benign cases were subjected to superficial parotidectomy and malignant cases to total parotidectomy with neck dissection.</p>

scholarly journals Increase in the incidence of parotid gland tumors in the years 2005–2014

2017 ◽  
Vol 71 (2) ◽  
pp. 29-34 ◽  
Author(s):  
Grażyna Stryjewska-Makuch ◽  
Bogdan Kolebacz ◽  
Małgorzata A. Janik ◽  
Agnieszka Wolnik
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Head And Neck ◽  
Cancer Incidence ◽  
Malignant Tumours ◽  
Parotid Glands ◽  
Upward Trend ◽  
Salivary Gland Tumours ◽  
Benign Tumours ◽  
Parotid Gland Tumours

Introduction: Salivary gland tumours account for 3-6% of tumours of the head and neck. About 80% of salivary gland tumors occur in parotid glands, 10-17% of which are malignant The aim of the study was to assess whether there is an upward trend in cancer incidence within the parotid glands, with particular emphasis on cancers. Materials and methods: 322 patients underwent surgery and 328 parotid gland tumours were removed in the years 2005-2014 at the Department of Laryngology and Laryngological Oncology of the Upper Silesian Medical Centre in Katowice-Ochojec. Clinical, histopathological and statistical analyses of the removed parotid gland tumours were performed. Results and discussion: A significant increase in the incidence of benign tumours, especially mixed and Warthin tumours, was demonstrated. There was no significant increase in the number of malignant tumours over the analysed period of time.

A Palatal Myoepithelioma

Dental Update ◽  
2019 ◽  
Vol 46 (7) ◽  
pp. 684-685
Author(s):  
Amandeep Bains ◽  
Thomas Dennis ◽  
Dimtrios Doumpiotis
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Oral Cavity ◽  
Clinical Relevance ◽  
Minor Salivary Glands ◽  
Parotid Glands ◽  
Rare Tumour ◽  
Salivary Gland Tumours ◽  
Rare Site ◽  
Benign Salivary Gland Tumours

This case report demonstrates the management of a myoepithelioma in the minor salivary glands of the palate. Myoepitheliomas are rare, benign, salivary gland tumours which usually affect the parotid glands. The rare neoplasms only account for 1–1.5% of all salivary gland neoplasms. This case shows a minimal approach to treating this rare tumour found in a rare site. CPD/Clinical Relevance: This case demonstrates the potential for rapid epithelial recovery within the oral cavity.

scholarly journals Papillary mucous cystadenoma of parotid gland

2017 ◽  
Vol 3 (12) ◽  
pp. 322
Author(s):  
Ananthaneni Anuradha ◽  
Undavalli Suresh Babu ◽  
Penumala Vignatha ◽  
Bagalad S. Bhavana
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Male Patient ◽  
Excisional Biopsy ◽  
Review Of Literature ◽  
Salivary Gland Tumours ◽  
Histopathological Features ◽  
Papillary Cystadenoma ◽  
Benign Salivary Gland Tumours

<p>Cystadenomas are rare benign salivary gland tumours characterised by prominent epithelium-lined papillary projections into the cystic spaces. Cystadenoma accounts for 2% of all salivary gland tumors, occurring most commonly in major salivary glands. Histopathologically there are two variants, papillary and mucinous variant. However very few cases are being reported in literature. We report a case of papillary cystadenoma occuring in parotid gland in a 28 year old male patient. Clinically, it presents as a soft, fluctuant, sessile and non-tender swelling measuring about 4×3.5 cm in diameter. Excisional biopsy was performed. The histopathological features were characteristic of papillary cystadenoma. This article highlights its clinical and histopathological features along with review of literature. </p>

Immunohistochemical Staining of Histological Fragments Derived from Salivary Gland Tumour Fine-Needle Biopsy Aspirates

2016 ◽  
Vol 61 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Marie Lundberg ◽  
Berent Munsterhjelm ◽  
Antti Mäkitie ◽  
Ilmo Leivo
Keyword(s):  
Salivary Gland ◽  
Fine Needle Biopsy ◽  
Added Value ◽  
University Hospital ◽  
Differential Diagnostics ◽  
Fine Needle ◽  
Salivary Gland Tumours ◽  
Pathology Reports ◽  
Gland Tumour ◽  
Malignant Diagnosis

Objectives: The aim of this study was to describe a method for analysing histological fragments derived from fine- needle aspirate biopsy (FNAB) of salivary gland tumours (SGTs), and to evaluate the use of immunohistochemistry (IHC) on them. Study Design: We reviewed all 509 FNAB pathology reports taken from SGTs at Helsinki University Hospital, Finland, between 1999 and 2009. In 51% of the cases (n = 209) “histo-fragments” had been obtained and 31 had been further analysed by IHC. Of these, 25 (81%) were available for review. We evaluated the benefit of IHC by relating its added value to the preoperative cytological diagnosis and its accuracy compared with the postoperative histological diagnosis. Results: Most of the samples analysed by IHC were assigned a malignant diagnosis, with 12 different types of malignancy represented. IHC was advantageous in 76% of the cases. In the 108 studies using IHC in this series, antibodies to 36 different antigens were used. Conclusion: Analysis of histo-fragments in FNABs using IHC can be valuable in specific differential diagnostics and raises diagnostic accuracy in SGTs.

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