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Science ◽  
2021 ◽  
Vol 374 (6565) ◽  
pp. 257-258
Author(s):  
Watcharop Chaikittisilp ◽  
Tatsuya Okubo
Keyword(s):  

2021 ◽  
Vol 5 (1) ◽  
pp. 64
Author(s):  
Hestu Wilujeng ◽  
Edi Irawan ◽  
Prahesti Tirta Safitri ◽  
Aan Subhan Pamungkas

The process of solving problems carried out by students in stages, namely understanding problems, planning solutions, carrying out solutions and checking again. Solving student problems varies according to the basic characteristics of students' interests, talents and potential. Learning will be more optimal if it is adjusted to the intelligence possessed by students. The goal is that teachers can facilitate learning according to the intelligence possessed by students, so the teacher must know the intelligence possessed by students. This research is a qualitative study using two subjects, namely the subject of linguistics and the subject of mathematical logic. The results showed that at the problem-understanding stage, SLM completed using formulas, completed according to plan and checked by recalculating. SL uses more trial-and-error reasoning, understanding information by reading sentences quickly as well as checking again.


2021 ◽  
pp. OP.20.00821
Author(s):  
Dax Kurbegov ◽  
Patricia Hurley ◽  
David M. Waterhouse ◽  
Nicholas J. Robert ◽  
Grzegorz S. Nowakowski ◽  
...  

PURPOSE: Feasibility assessments (FAs) are important to establish site capabilities to conduct clinical trials and their suitability for specific trials. However, current FA methods used by biotechnology and pharmaceutical (biotech-pharma) trial sponsors and contract research organizations (CROs) are costly, inefficient, unnecessarily burdensome, and resource intensive. These methods delay trial start-up, act as a barrier to site participation, and ultimately reduce timely patient access to clinical trials and novel treatments. METHODS: An ASCO Task Force was convened to assess the specific burdens and challenges with FAs and to develop recommendations to improve their efficiencies and effectiveness. Stakeholders (including trial sites, biotech-pharma sponsors, and CROs) provided insights into challenges and offered solutions through two surveys and an in-person meeting. The Task Force used the feedback to formulate consensus recommendations to improve FAs for oncology clinical trials. RESULTS: Three key recommendations were identified for application across all biotech-pharma sponsored trials: (1) implement a streamlined and uniform FA process across trials and sponsors; (2) minimize and standardize questions; and (3) leverage technology to centralize FAs, facilitate communications, and reduce redundancies. CONCLUSION: There is an urgency to improve the current FA process, which is costly, inconsistent, inefficient, labor intensive, and of uncertain effectiveness. All stakeholders stand to benefit from implementing these recommendations, which aim to minimize burdens and ensure that more trial sites and patients have timely access to oncology clinical trials. To have meaningful impact, adoption and consistent execution of these recommendations across all trials, sponsors, CROs, and sites are essential.


In almost every organization where user sensitive data is available, security and privacy of the data plays a vital role..As storage of these information is overhead in database, Tokens are generated which handles sessions and also self contains user details. One of such widely used stateless token is Json Web Token. This paper deals with the research that follows implementation of authentication and authorization technique using JSON web token which will make web service a role based one .In the project under taken, Json web token is generated in a more secured way by choosing the secret key for web token wisely. Usually key for the token was a mere string or the set of keys stored in a key ring in the database and used alternately for the users to create the token. Or one more trial model is created where captcha was used in short a random number was generated and used as secret key for token generation but the main issue was increased storage. Thus storage is tried to reduce also less predictive secret key is generated in this project.


Author(s):  
Qike Jia ◽  
Hongliang Chen ◽  
Xuewei Chen ◽  
Qichuan Tang

Purpose: The current study aims to explore the barriers for middle-aged Chinese to learn about and uptake low-dose computed tomography (LDCT) lung cancer screening. Methods: Data were collected via an online survey in December 2019. Final valid sample included 640 respondents, aged 40–60 years old, from 21 provinces of China. We performed multiple linear regressions to test the potential barriers to LDCT scan. Findings: Cost concerns, distrust in doctors, fears of disease, lack of knowledge, and optimistic bias are negatively associated with the intention to learn about and uptake LDCT scan. Implications: Our study contributes to understanding the negative predictors of middle-aged Chinese to get LDCT lung cancer scans. Future campaign programs should help audiences to build comprehensive understandings about lung cancer and LDCT scan. To better promote LDCT scan in China, the government should fund more trial programs continuously and public efforts should be made to rebuild the patient–doctor trust.


2018 ◽  
Vol 127 (11) ◽  
pp. 848-855 ◽  
Author(s):  
Steven Micucci ◽  
David B Keschner ◽  
Jonathan Liang

Objectives: To review the role of eustachian tube balloon dilation (ETBD) in the setting of chronic Eustachian tube dysfunction (ETD) and ascertain how ETBD is currently being used in practice today. Methods: An online survey included 20 questions designed by 3 investigators to examine how otolaryngologists utilize ETBD in the management of ETD. The survey was distributed to the members of the American Rhinologic Society (ARS), American Otological Society (AOS), and American Neurotology Society (ANS) in their respective annual electronic mailings in April and May of 2017. Results: A total of 1105 and 633 surveys were sent to ARS and AOS/ANS members, respectively. Of those, 157 surveys were returned (126 from ARS and 31 from AOS/ANS). Of those returning the survey, 72 (50%) had not performed ETBD and were excluded from subsequent analysis. Forty-four (66%) respondents consider ETBD after failure of medical management; conversely, 18 (27%) and 26 (39%) consider ETBD after failure of 1 or more trial of myringotomy tube placement. Routine testing for ETBD includes audiogram with tympanometry 64 (96%) and preoperative computer tomography (CT) 38 (57%). Fifty-three (80%) practitioners only perform ETBD in adults 18 years and older. Thirty-four (53%) respondents describe ETBD as “great” or “good,” while 27 (42%) were unsure, and only 3 (5%) did not like ETBD. Conclusions: Eustachian tube balloon dilation is a novel technique for the treatment of chronic ETD, and its role continues to evolve and develop. Current practice patterns demonstrate wide variability in the assessment of ETD, heterogeneity in the timing of ETBD, and controversy in preoperative CT screening.


2018 ◽  
Vol 4 (5) ◽  
pp. FSO299 ◽  
Author(s):  
Svenja Dieffenbacher ◽  
Stefanie Zschäbitz ◽  
Luisa Hofer ◽  
Gencay Hatiboglu ◽  
Weibin Hou ◽  
...  

2018 ◽  
Vol 37 (7) ◽  
pp. 2017-2018
Author(s):  
Patrick Durez ◽  
Karel Pavelka ◽  
Maria Alicia Lazaro ◽  
Abraham Garcia-Kutzbach ◽  
Robert J. Moots ◽  
...  

2018 ◽  
Vol 37 (5) ◽  
pp. 1417-1420 ◽  
Author(s):  
Patrick Durez ◽  
Karel Pavelka ◽  
Maria Alicia Lazaro ◽  
Abraham Garcia-Kutzbach ◽  
Robert J. Moots ◽  
...  

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