pdgfrb rearrangement
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Myeloid neoplasm with a novel cryptic PDGFRB rearrangement detected by next-generation sequencing

2020 ◽  
Vol 244 ◽  
pp. 55-59
Author(s):  
Nives Zimmermann ◽  
Mehdi Nassiri ◽  
Jiehao Zhou ◽  
Adam M. Miller ◽  
Shanxiang Zhang
Keyword(s):  
Next Generation Sequencing ◽  
Next Generation ◽  
Myeloid Neoplasm ◽  
Generation Sequencing ◽  
Pdgfrb Rearrangement

scholarly journals A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia

2020 ◽  
Vol 4 (3) ◽  
pp. 445-448 ◽  
Author(s):  
Max Jan ◽  
Daniel E. Grinshpun ◽  
Julian A. Villalba ◽  
Paola Dal Cin ◽  
David B. Sykes ◽  
...  
Keyword(s):  
Cell Culture ◽  
Rna Sequencing ◽  
Myeloid Neoplasm ◽  
Key Points ◽  
Normal Fish ◽  
Pdgfrb Rearrangement

Key Points Targeted RNA sequencing detected a cryptic G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia and normal FISH studies. Consistent with the patient’s response to imatinib, we demonstrate this rearrangement is oncogenic and sensitive to TKI in cell culture.

scholarly journals Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib

2019 ◽  
Vol 5 (5) ◽  
pp. a004440 ◽  
Author(s):  
Mohammed Hassan ◽  
Erin Butler ◽  
Raphael Wilson ◽  
Angshumoy Roy ◽  
Yanbin Zheng ◽  
...  
Keyword(s):  
Infantile Myofibromatosis ◽  
Pdgfrb Rearrangement

scholarly journals Abnormal mast cells in myeloid neoplasm with eosinophilia and PDGFRB rearrangement

Blood ◽  
2019 ◽  
Vol 134 (8) ◽  
pp. 718-718
Author(s):  
Marie-Charlotte Bourrienne ◽  
Jérôme Debus
Keyword(s):  
Mast Cells ◽  
Myeloid Neoplasm ◽  
Pdgfrb Rearrangement

scholarly journals Molecular monitoring of patients with ETV6-PDGFRB rearrangement: Implications for therapeutic adaptation

2017 ◽  
Vol 182 (1) ◽  
pp. 148-152
Author(s):  
Audrey Bidet ◽  
Claudine Chollet ◽  
Martine Gardembas ◽  
Franck E. Nicolini ◽  
Philippe Genet ◽  
...  
Keyword(s):  
Molecular Monitoring ◽  
Pdgfrb Rearrangement

scholarly journals A Case of Myeloid Neoplasm with a PDGFRB Rearrangement and Eosinophilia

2017 ◽  
Vol 92 (1) ◽  
pp. 79-83
Author(s):  
Nam Gil Cho ◽  
Daejin Kim ◽  
Minjung Shim ◽  
So Young Chong
Keyword(s):  
Myeloid Neoplasm ◽  
Pdgfrb Rearrangement

Novel Chromosome 5 Inversion Associated With PDGFRB Rearrangement in Hypereosinophilic Syndrome

2016 ◽  
Vol 152 (12) ◽  
pp. 1391 ◽  
Author(s):  
Jennifer N. Saultz ◽  
Ben H. Kaffenberger ◽  
Montoya Taylor ◽  
Nyla A. Heerema ◽  
Rebecca Klisovic
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Chromosome 5 ◽  
Pdgfrb Rearrangement
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