scholarly journals Myeloid/Lymphoid Neoplasms with PDGFRB Rearrangement

2020 ◽  
Author(s):  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Antonia Morey-Matamalas ◽  
Enric Vidal ◽  
Jorge Martínez ◽  
Jaume Alomar ◽  
Antonio Ramis ◽  
...  

Abstract Background The present paper reviews the occurrence of neoplasms in swine and presents a case series of 56 tumors submitted to the Slaughterhouse Support Network (Servei de Suport a Escorxadors [SESC] IRTA-CReSA]) from slaughtered pigs from 1998 to 2018 (April) in Catalonia (Spain). The aim of the study was to describe the spectrum of spontaneous neoplastic lesions found in slaughtered pigs and to compare the reported tumor cases with previous published data. Lymphoid neoplasms were characterized and classified using the WHO classification adapted for animals. Results The most reported neoplasm during this period was lymphoma (28). Within lymphomas, the B-cell type was the most common, being the diffuse large B-cell lymphoma (15/28) the most represented subtype. Other submitted non-lymphoid neoplasms included melanoma (7), nephroblastoma (3), mast cell tumor (2), liposarcoma (2), osteochondromatosis (2), papillary cystadenocarcinoma (1), peripheral nerve sheath tumor (1), lymphoid leukemia (1), fibropapilloma (1), hemangiosarcoma (1), hepatoma (1), histiocytic sarcoma (1), pheochromocytoma (1) and osteosarcoma (1). Conclusions The existence of a well-established Slaughterhouse Support Network allowed the compilation of comprehensive data for further epidemiological and pathological studies, particularly about less commonly reported lesions in livestock such as neoplasms in pigs.


Pathology ◽  
2017 ◽  
Vol 49 ◽  
pp. S39
Author(s):  
Sue Morgan
Keyword(s):  

2021 ◽  
Vol 21 ◽  
pp. S66-S68
Author(s):  
Andreas Reiter ◽  
Nicholas C.P. Cross ◽  
Jason Gotlib

2010 ◽  
Vol 67 (10) ◽  
pp. 664-672 ◽  
Author(s):  
L. Orsi ◽  
A. Monnereau ◽  
B. Dananche ◽  
C. Berthou ◽  
P. Fenaux ◽  
...  

Cancer ◽  
2004 ◽  
Vol 102 (3) ◽  
pp. 174-185 ◽  
Author(s):  
Eugene V. Sheval ◽  
Janna V. Churakova ◽  
Oksana A. Dudnik ◽  
Ivan A. Vorobjev

Blood ◽  
2008 ◽  
Vol 112 (12) ◽  
pp. 4384-4399 ◽  
Author(s):  
Elaine S. Jaffe ◽  
Nancy Lee Harris ◽  
Harald Stein ◽  
Peter G. Isaacson

AbstractIn the past 50 years, we have witnessed explosive growth in the understanding of normal and neoplastic lymphoid cells. B-cell, T-cell, and natural killer (NK)–cell neoplasms in many respects recapitulate normal stages of lymphoid cell differentiation and function, so that they can be to some extent classified according to the corresponding normal stage. Likewise, the molecular mechanisms involved the pathogenesis of lymphomas and lymphoid leukemias are often based on the physiology of the lymphoid cells, capitalizing on deregulated normal physiology by harnessing the promoters of genes essential for lymphocyte function. The clinical manifestations of lymphomas likewise reflect the normal function of lymphoid cells in vivo. The multiparameter approach to classification adopted by the World Health Organization (WHO) classification has been validated in international studies as being highly reproducible, and enhancing the interpretation of clinical and translational studies. In addition, accurate and precise classification of disease entities facilitates the discovery of the molecular basis of lymphoid neoplasms in the basic science laboratory.


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