Changes in Electrical Conductance of Polymer Composites Melts Due to Carbon Nanofiller Particles Migration

In this work, the results of investigation of the effect of polymer composite melts electrical conductance increase with time are presented. The conductance time dependencies were obtained for composites based on polypropylene filled with carbon nanoparticles of different types. The dependencies were analyzed to demonstrate the possibility of correlation of the conductance kinetics with different composite parameters, such as the filler geometry. Additional studies were carried out, such as electron microscopy study, conductance measurements after consecutive surface layer removal, and composite melt conductance measurements using a three-electrode scheme. The results showed that the increased electrical conductance of the composite materials can be attributed to the formation of an enriched with the filler particles surface layer, which happens during the stay of the composite in a melt state. Analysis of the experimental data, along with the results of numerical modeling, allowed to suggest a possible filler distribution transformation scheme. The physical premises behind the investigated effect are discussed.

Single-Molecule Junction Origami

Stimuli-responsive molecular junctions, where the conductance can be altered by an external perturbation, are an important class of nanoelectronic devices. These have recently attracted interest as large effects can be introduced through exploitation of quantum phenomena. We show here that significant changes in conductance can be attained as a molecule is repeatedly compressed and relaxed, resulting in molecular folding along a flexible fragment and cycling between an <i>anti</i> and a <i>syn </i>conformation. Power spectral density analysis and DFT transport calculations show that through-space tunnelling between two phenyl fragments is responsible for the conductance increase as the molecule is mechanically folded to the <i>syn</i> conformation. This phenomenon represents a novel class of mechanoresistive molecular devices, where the functional moiety is embedded in the conductive backbone and exploits intramolecular nonbonding interactions, in contrast to most studies where mechanoresistivity arises from changes in the molecule-electrode interface.

Single-Molecule Junction Origami

Stimuli-responsive molecular junctions, where the conductance can be altered by an external perturbation, are an important class of nanoelectronic devices. These have recently attracted interest as large effects can be introduced through exploitation of quantum phenomena. We show here that significant changes in conductance can be attained as a molecule is repeatedly compressed and relaxed, resulting in molecular folding along a flexible fragment and cycling between an <i>anti</i> and a <i>syn </i>conformation. Power spectral density analysis and DFT transport calculations show that through-space tunnelling between two phenyl fragments is responsible for the conductance increase as the molecule is mechanically folded to the <i>syn</i> conformation. This phenomenon represents a novel class of mechanoresistive molecular devices, where the functional moiety is embedded in the conductive backbone and exploits intramolecular nonbonding interactions, in contrast to most studies where mechanoresistivity arises from changes in the molecule-electrode interface.

Solvent-mediated conductance increase of dodecanethiol-stabilized gold nanoparticle monolayers

Gold nanoparticle monolayers provide convenient templates to study charge transport in organic molecules beyond single junction techniques. Conductance is reported to increase by several orders of magnitude following immersion of alkanethiol-stabilized gold nanoparticle monolayers in a solution containing conjugated thiol-functionalized molecules. Typically, this observation is attributed to molecular exchange. Less attention has been paid to the role of the solvent alone. Here, we report on an increase in conductance of dodecanethiol-stabilized gold nanoparticle monolayers on Si/SiO2 by an average factor of 36 and 22 after immersion in pure ethanol (EtOH) and tetrahydrofuran (THF), respectively. Analysis by scanning electron microscopy (SEM) and small-angle X-ray scattering (SAXS) reveals a solvent-induced decrease in lattice constant of close-packed monolayers. We compare the conductance of the monolayer after molecular exchange with two different oligophenylenes to shed light on the respective contribution of the solvent-induced structural change and the molecular exchange itself on the conductance increase.

Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: Relevance to trypanosome lysis

Apolipoprotein L-1 (APOL1), the trypanolytic factor of human serum, can lyse several African trypanosome species includingTrypanosoma brucei brucei, but not the human-infective pathogensT. brucei rhodesienseandT. brucei gambiense, which are resistant to lysis by human serum. Lysis follows the uptake of APOL1 into acidic endosomes and is apparently caused by colloid-osmotic swelling due to an increased ion permeability of the plasma membrane. Here we demonstrate that nanogram quantities of full-length recombinant APOL1 induce ideally cation-selective macroscopic conductances in planar lipid bilayers. The conductances were highly sensitive to pH: their induction required acidic pH (pH 5.3), but their magnitude could be increased 3,000-fold upon alkalinization of the milieu (pKa= 7.1). We show that this phenomenon can be attributed to the association of APOL1 with the bilayer at acidic pH, followed by the opening of APOL1-induced cation-selective channels upon pH neutralization. Furthermore, the conductance increase at neutral pH (but not membrane association at acidic pH) was prevented by the interaction of APOL1 with the serum resistance-associated protein, which is produced byT. brucei rhodesienseand prevents trypanosome lysis by APOL1. These data are consistent with a model of lysis that involves endocytic recycling of APOL1 and the formation of cation-selective channels, at neutral pH, in the parasite plasma membrane.

Electrophysiological evidence of GABAA and GABAC receptors on zebrafish retinal bipolar cells

To refine inhibitory circuitry models for ON and OFF pathways in zebrafish retina, GABAergic properties of zebrafish bipolar cells were studied with two techniques: whole cell patch responses to GABA puffs in retinal slice, and voltage probe responses in isolated cells. Retinal slices documented predominantly axon terminal responses; isolated cells revealed mainly soma-dendritic responses. In the slice, GABA elicited a conductance increase, GABA responses were more robust at axon terminals than dendrites, and Erev varied with [Cl−]in. Axon terminals of ON- and OFF-type cells were similarly sensitive to GABA (30–40 pA peak current); axotomized cells were unresponsive. Bicuculline-sensitive, picrotoxin-sensitive, and picrotoxin-insensitive components were identified. Muscimol was as effective as GABA; baclofen was ineffective. Isolated bipolar cells were either intact or axotomized. Even in cells without an axon, GABA or muscimol (but not baclofen) hyperpolarized dendritic and somatic regions, suggesting significant distal expression. Median fluorescence change for GABA was −0.22 log units (∼ −16 mV); median half-amplitude dose was 0.4 μM. Reduced [Cl−]out blocked GABA responses. GABA hyperpolarized isolated ON-bipolar cells; OFF-cells were either unresponsive or depolarized. Hyperpolarizing GABA responses in isolated cells were bicuculline and TPMPA insensitive, but blocked or partially blocked by picrotoxin or zinc. In summary, axon terminals contain bicuculline-sensitive GABAA receptors and both picrotoxin-sensitive and insensitive GABAC receptors. Dendritic processes express zinc- and picrotoxin-sensitive GABAC receptors.

Rapid Electrical Sintering of Nanoparticle Stuctures

ABSTRACTA method for rapid electrical sintering (RES) of nanoparticle structures on temperature-sensitive substrates is presented. For an inkjetted silver nanoparticle conductor, a conductance increase of five orders of magnitude is demonstrated to occur in a timescale that typically varies between a few and one hundred milliseconds depending on process parameters. Furthermore, most of the conductance change takes only a few microseconds. The achievable final conductivities are within a factor of two from the bulk silver conductivity, as calculated using the external geometric dimensions of the structure ignoring porosity. The method is also applicable to other inorganic conductors such as indium-tin-oxide (ITO). More generally, the method offers a versatile tool in nanotechnology for electrical functionalization of nanoparticle structures. The method is also potentially suited for mass production.