Mediated Narratives of Syrian Refugees : Mapping Victim–Threat Correlations in Turkish Newspapers

Turkey has become the first and main transition hub for Syrian refugees. Furthermore, Turkey is spatially as well as culturally simultaneously referred to as European and Asian or Middle Eastern depending the point of view. Therefore, the representation of refugees in the Turkish press proves significant for the knowledge produced about refugees. Accordingly, this chapter strives to investigate the coverage of Syrian refugees in newspapers, which constitutes only one aspect of the overall reception of the issue in Turkey, and therefore does not claim to be exhaustive. Yet, because daily newspapers are still among the most important media sectors in Turkey, they constitute a special case of knowledge production worth investigating.

MILITARY-ESTATE CODES IN MEDIEVAL JAPAN: ERA OF THE FIRST SHOGUNATES

The phenomenon of clan-regional rulemaking during the military-oligarchic regime in medieval Japan is studied for the first time. The purpose of the study was a comparative analysis of the texts of the largest princely codes of daimyo and military houses, as well as the norms of the Bushido code . The analysis was carried out on the basis of historical-genetic and synchronous-logical methods using Japanese primary sources with a survey translation, as well as scientific and abstract materials of Japanese, English and Russian medieval studies. Among the results achieved, a typology and hierarchy of sources of traditional law of the Shogun period are identified. The evolution of the system of law sources from the Kamakura shogunate to the Miromati dynasty is traced. One of the most striking monuments of Kamakur law is examined (the military-estate code Goseibai Sikimoku, 1232). Its sources, structure, technic mode and criminal provisions are studied. The analysis of the Bushido code showed that this quasi-legal regulator of the samurai behavior was an eclectic code of norms and rules for the bushi warriors with their ideals of loyalty and patriotism. The main transition to a new stage in the legal history of Japan after the Kammu сode, 1336 and during the period of Warring Provinces was established. It was distinguished by an increase in the number and significance of local law monuments - princely and clan codes, city statutes and charters of merchants' houses. From this list, the author singled out and compared in juridical techniques the ten large bunkokuho codes published by the largest princes- daimyo in order to systematize local laws and streamline the administrative-judicial system.

Ordering Phase Transition with Symmetry-Breaking from Disorder over Non-Equivalent Sites: Calorimetric and Crystallographic Study of Crystalline d-Sorbose

Phase transitions in the crystalline state of chiral sorbose were examined using precise heat capacity calorimetry and X-ray crystallography. The calorimetry established heat capacity below room temperature. Besides the known transition (main transition) at 199.5 K, the calorimetry detected plural thermal anomalies assignable to new phase transitions (around 210 K) and a glass transition (at ca. 120 K). The X-ray diffraction at low temperatures established the crystal structure of the lowest temperature phase. The identification of the broken symmetry upon the main transition solves an apparent contradiction that the structural disorder reported previously does not contribute seemingly to the symmetrization.

Passive Double Skin Façade (DSF) Basic Components and Functions

Efficient building design is not impossible to be achieved in construction industry. Due to the various environmental issues that related to the building design, architects and people in the construction industry try to create an environmental friendly building design. Function as the main transition building element, building facade plays a major role to control and prevent the unnecessary elements from outside to enter the interior building space. Double Skin Facade (DSF) possessed a high potential to provide multifunction benefits to the building design, human and environment. There are various definitions that being applied to defined each of the DSF design and functions. This paper reveals some of the definitions and functions that related to the basic components for DSF such as cavity, inner and outer skin glaze facade and shading device. Each of the DSF's components has its own functions to provide a better building design. Information regarding on each of the DSF's components are highlighted that base on the literature review. All of the information is tabulates to identify the percentage of each basic component for DSF. This research reveals the definitions and functions regarding on the basic component for passive DSF as a source to increase the understanding and knowledge especially for those who are involved in the construction industry

Critical Discussion of the Belief Model

Chapter 6 argues that most of the reductive assumptions put forward by the Belief Model are wrong. It rejects the view that suspended judgement is nothing but the absence of belief and disbelief, and likewise rejects the view that disbelief is nothing but belief-in-negation. Thought experiments demonstrate that all three types of coarse-grained attitude are self-standing elements of our rational architecture. It is shown that norms for belief put forward by the Belief Model do not morph automatically into norms for disbelief or suspended judgement. Then it is shown that the model’s main transition rule does not function at all like rational shift of belief in ordinary life.

About transition processes in blasthole drilling at quarries

As a system, the mining enterprise develops under constantly changing conditions of the external and internal environment. These conditions affect the state of the most important drilling subsystem: blasthole drilling technology, safety, performance, power consumption of the boring rigs and roller bits used. The main transition processes as necessary responses of the subsystem to changing conditions were identified as a result of fragmentary data analysis showing decisions taken over the past 15-20 years, which increase drilling activity efficiency and safety of smaller quarries of Russia, which contain a significant amount of material resources. The main transition processes contribute to the growth of drilling performance and consist of changing the following: bit design for specific rocks; drilling method; drilling mode; boring rig design; controlled parameters of drilling process and rock properties redetermination; parameters of maintenance and repair system. Based on the performed analysis, the systematization results of the main factors predetermining the need for transition processes implementation in the “drilling operations” subsystem were obtained and presented. The proposed approach allowed to reveal a holistic picture of the main interacting factors in the “drilling operations” subsystem. Based on the factors systematization presented in the article it is possible to envisage changes of individual factors depending on changes of other factors, not functionally related directly when planning drilling operations.

Value-semantic factors of teachers’ professional growth in the context of the longevity problem

The article discusses the study results of the Russian teachers’ professional longevity. The authors try to highlight the role of value-semantic factors that determine the teacher’s orientation to the productive extension of his professional path beyond the retirement age. The study results, in particular, the analysis of data from in-depth interviews with teachers of retirement age (n = 40) allows us to assert a significant contribution of value-semantic factors to the overall picture of the process of a teacher’s transition to the post-professional period of his life. In particular, three main transition strategies are identified: 1. Postponement; 2. Smooth transition; 3. Forced finish. Each strategy corresponds to a certain type of indicators of a value-semantic nature: attitude to health, attitude to the level of one’s professional efficiency, combining professional and personal goals. There is a high diagnostic value of the metaphor method in the study of the respondents’ professional path.

Influence of Lipid’s Main Transition Temperature on the Stability of Chimeric Liposomal Systems

Background: The incorporation of polymeric components into liposomes promotes structural rearrangement of the lipid bilayers that could affect their properties and their behavior. Therefore, by mixing phospholipids with polymeric compounds the, socalled chimeric liposomal nanosystems are produced and could be advantageous, compared with conventional (e.g. composed of pure phospholipids) liposomal nanostructures. Objective: In this work, we used lipids with different main transition temperature (Tm) i.e 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC, Tm=55°C), L-α-phosphatidylcholine, hydrogenated (Soy) (HSPC, Tm=52 °C) and egg phosphatidylcholine (EggPC, Tm=23 °C) and we studied and compared the physicochemical characteristics and the stability of conventional with that of chimeric liposomes. Methods: Thin-film hydration method (TFH) was used as the preparation protocol for all systems. Dynamic and electrophoretic light scattering (DLS and ELS) were utilized in order to elucidate the physicochemical characteristics of all systems. All liposomal systems exhibited sizes below 100nm while the ζ-potential was around zero, indicating the absence of surface charge. Results: The results revealed that the Tm of each phospholipid influences the biophysical behavior of the lipidic membrane, which contributes to the physicochemical characteristics and affects the physical stability of the liposomal nanosystems. The nature and physicochemical properties of each phospholipid seem to play a key role, regarding the structural characteristics and the formation process of the liposomal nanosystems. Conclusion: : Comparing the physicochemical properties of the conventional liposomes with those of the chimeric liposomal systems, we conclude that the complexity of the latter, due to the incorporation of the polymeric guest into the lipidic bilayer, revealed new properties, which correspond to increased physical stability.

Thermal and Chemical Unfolding of a recombinant monoclonal IgG1 antibody: Application of the Multi-State Zimm-Bragg Theory

The thermal unfolding of a recombinant monoclonal antibody IgG1 (mAb) was measured with differential scanning calorimetry (DSC). The DSC thermograms reveal a pre-transition at 72°C with an unfolding enthalpy of ΔHcal ∼ 200-300 kcal/mol and a main transition at 85 °C with an enthalpy of ∼900 - 1000 kcal/mol. In contrast to single-domain molecules, mAb unfolding is a complex reaction that is analysed with the multi-state Zimm-Bragg theory. For the investigated mAb, unfolding is characterised by a cooperativity parameter σ ∼10−4 and a Gibbs free energy of unfolding of gnu ∼100 cal/mol per amino acid. The enthalpy of unfolding provides the number of amino acid residues v participating in the unfolding reaction. On average, v∼220±50 amino acids are involved in the pre-transition and v∼850±30 in the main transition, accounting for ∼90% of all amino acids. Thermal unfolding was further studied in the presence of guanidineHCl. The chemical denaturant reduces the unfolding enthalpy ΔHcal and lowers the midpoint temperature T0. Both parameters depend linearly on the concentration of denaturant. The guanidineHCl concentrations needed to unfold mAb at 25 °C are predicted to be 2-3 M for the pre-transition and 5-7 M for the main transition, varying with pH. GuanidineHCl binds to mAb with an exothermic binding enthalpy, which partially compensates the endothermic mAb unfolding enthalpy. The number of guanidineHCL molecules bound upon unfolding is deduced from the DSC thermograms. The bound guanidineHCl-to-unfolded amino acid ratio is 0.79 for the pre-transition and 0.55 for the main transition. The pre-transition binds more denaturant molecules and is more easily destabilised than the main transition.Overall, the current study shows the strength of the Zimm-Bragg model for the quantitative description of unfolding events of large, therapeutic proteins, such as a monoclonal antibody.Statement of significanceFirst quantitative thermodynamic study of an antibody with differential scanning calorimetry and analyzed with the multi-state Zimm-Bragg theory.

Emerging Technologies in Mass Spectrometry-Based DNA Adductomics

The measurement of DNA adducts, the covalent modifications of DNA upon the exposure to the environmental and dietary genotoxicants and endogenously produced electrophiles, provides molecular evidence for DNA damage. With the recent improvements in the sensitivity and scanning speed of mass spectrometry (MS) instrumentation, particularly high-resolution MS, it is now feasible to screen for the totality of DNA damage in the human genome through DNA adductomics approaches. Several MS platforms have been used in DNA adductomic analysis, each of which has its strengths and limitations. The loss of 2′-deoxyribose from the modified nucleoside upon collision-induced dissociation is the main transition feature utilized in the screening of DNA adducts. Several advanced data-dependent and data-independent scanning techniques originated from proteomics and metabolomics have been tailored for DNA adductomics. The field of DNA adductomics is an emerging technology in human exposure assessment. As the analytical technology matures and bioinformatics tools become available for analysis of the MS data, DNA adductomics can advance our understanding about the role of chemical exposures in DNA damage and disease risk.