Novel Elastomer Materials for Extreme Temperature Operation in Subsea Thermal Insulation Applications at Unlimited Water Depth

Rubber based systems have been used in subsea thermal insulation for many years and have proven themselves to be reliable and cost efficient. Formulations have been changed over the years, pressing the maximum usage temperature upwards and into the realm of 160 to180°C in a hot-wet environment. Until recently there was a need for high temperature along with pressure vessels (autoclaves) for vulcanisation. This has limited the widespread use of such systems. Recent changes have eliminated the need for autoclaves, however the high temperature vulcanisation hasstill been required. A novel formulation has been developed to address these shortcomings, so that this class of materials could have wider use. This new material employs freely available materials in a unique blend. The material contains no hydrolysable groups and can operate from −40°C to 180°C continuously in air and in a hot-wet environment and retains its resilience and flexibility; and thus opening for use in both high and low temperature systems. The formulation does not include the use of hollow glass microspheres and is, correspondingly, without water depth limitations. A new, highly reliable vulcanisation chemistry allows for a stable latency time for application, with vulcanisation temperatures reduced to 50°C. This allows for rapid hand application and simultaneous vulcanisation on subsea trees, valves, manifolds, etc. The material is self-agglomerating, merging under gentle pressure, and can be applied at high thickness. As the base material has an intrinsically low thermal conductivity, glass-based fillers are not needed. The material adheres well to painted or primed surfaces and to many other materials typically used in the offshore thermal insulation industry. The 2-component material is conveniently combined on site, reducing the need for refrigeration during transport and easing mobilisation logistics and is applied using simple hand tools. Extruded profiles can be used directly on complex structures or combined into sheets for ease of application on more regular shapes in order to optimise application rates. Moulds are not required for application, reducing engineering and fabrication cost, while also shortening mobilisation time. The system has been extensively qualified according to ISO 12736 for continuous use at 180°C. This paper will detail important aspects of the development project along with the results of the qualification testing.

Closure Techniques

The superficial location of the radial artery access site eliminates the need for overly specialized closure devices. Manual compression is considered the gold standard technique. Closure devices in their many iterations are designed to work by applying continuous pressure using an adjustable balloon. They are arguably superior to manual compression as they exert a continuous and gentle pressure on the artery. The simplest, and cheapest devices might be the best ones. A good closure technique ensures compression with a “just needed” intensity to maintain anterograde flow. A good technique also incorporates the principle of patent hemostasis with or without prophylactic ulnar artery occlusion while keeping the whole process relatively simple. These techniques result in fewer radial artery occlusions and other complications. Lower complications ensure patency of the radial artery for future procedures.

Novel approach to engage left main coronary artery in aneurysmally dilated aortic root

Aneurysmally dilated aortic route pose a considerable challenge in invasive coronary angiography (CAG) using routine workhorse catheters. Often one has to resort to either CT CAG which is not possible in all cases or use other techniques described in literature which may be technically challenging. We report a novel technique using multipurpose-1 (MPA-1) catheter. By applying gentle pressure, MPA-1 can be shaped to conform to aortic root anatomy by forming a primary and secondary loop. This makes engagement of left main ostium easy and atraumatic.

Barnacle-Inspired Paste for Instant Hemostatic Tissue Sealing

Whilst sealing damaged tissues by adhesives has potential advantages over suturing or stapling, existing tissue adhesives cannot form rapid or robust adhesion on tissues covered with body fluids such as blood. In contrast, the glues of barnacles, consisting of a lipid-rich matrix and adhesive proteins, and can strongly adhere to wet and contaminated surfaces. Here we report a barnacle-inspired paste capable of forming instant robust hemostatic sealing of diverse tissues. The paste is composed of a hydrophobic oil matrix and bioadhesive microparticles to implement the barnacle-inspired mechanism to repel blood through the hydrophobic matrix. Subsequently, the bioadhesive microparticles crosslink with underlying tissues under gentle pressure. The barnacle-inspired paste can provide tough (interfacial toughness over 300 J m-2) and strong (shear and tensile strength over 70 kPa, burst pressure over 350 mmHg) hemostatic sealing of a broad range of tissues within five seconds. We validate in vitro and in vivo biocompatibility and biodegradability of the barnacle-inspired paste in rodent models. We further demonstrate potential applications of the barnacle-inspired paste for instant hemostatic sealing in ex vivo porcine aorta, in vivo rat liver and heart models.

EFEKTIVITAS EFFLEURAGE MASSAGE UNTUK MENGURANGI NYERI PUNGGUNG PADA IBU HAMIL TRIMESTER III DI RB CI SEMARANG

Background: About 80% of women will feel back pain at some point during pregnancy. Most back pain during pregnancy occurs due to changes in the spinal muscles which are as much as 70%. and 30% of back pain during pregnancy may be due to irregularities in the condition of the spine that occurred earlier. Effleurage massage is a form of massage by using a palm that gives a gentle pressure to the top of the body in a circular direction repeatedly.Purpose: Knowing the scale of pain in pregnant women who have back trimester III back pain before and after effleurage massage done at RB CI Semarang.Research methods: Type of research used quantitative method, population in this research is trimester III pregnant woman in RB CI Semarang a number of 40 Respondent with collecting data obtained by doing effleurage massage with pre experimental design using pretest - postest one group design. Sampling technique in this research use Purposive Sampling technique.Results: the results obtained before the effleurage massage performed on pregnant women on average - scale pain 7, while after effleurage massage performed on average pregnant women decreased to pain scale 3. Conclusion:There is effect of effleurage massage on back pain in pregnant mother of trimester III.Keywords: effleurage massage, back painLiterature : 17 (2005 – 2017 ) AbstractAbout 80% of women will feel back pain at some point during pregnancy. Most back pain during pregnancy occurs due to changes in the spinal muscles which are as much as 70%. and 30% of back pain during pregnancy may be due to irregularities in the condition of the spine that occurred earlier.Effleurage massage is a form of massage by using a palm that gives a gentle pressure to the top of the body in a circular direction repeatedly.Knowing the scale of pain in pregnant women who have back trimester III back pain before and after effleurage massage done at RB CI Semarang.Type of research used quantitative method, population in this research is trimester III pregnant woman in RB CI Semarang a number of 40 Respondent with collecting data obtained by doing effleurage massage with pre experimental design using pretest - postest one group design. Sampling technique in this research use Purposive Sampling technique.the results obtained before the effleurage massage performed on pregnant women on average - scale pain 7, while after effleurage massage performed on average pregnant women decreased to pain scale 3. There is effect of effleurage massage on back pain in pregnant mother of trimester III.Keywords:effleurage massage, back pain

A High-Loaded Axial Compressor Bifurcate Stator Blade Aerodynamic Design and Vorticity Dynamics Diagnosis for Flow Structure

On the flow instability caused by large scale boundary-layer flow separation in highly loaded compressor/fan blade passage, a novel bifurcate compressor blade is designed based on pressure gradient control idea for blade passage flow, and a distinctive variable solidity bifurcate blade concept and three-dimensional blade design technology are integrated to achieve this design idea in this paper. The quantitative flow information for the bifurcate blade passage is obtained by numerical simulation method to investigate the separation flow structure and dynamic mechanism near the wall and in the wake flow area. Besides, the complex influence of vortex structure evolution and the dynamic mechanism of low energy fluid redistribution being controlled in boundary-layer flow area would be revealed by applying the vorticity dynamics theory. The variable law of design parameters is explored in order to decrease aerodynamic loss, to delay flow separation near the wall and corner for the blade surface, to restructure blade aerodynamic loading, to form gentle pressure gradient and to diminish wake flow loss. The results indicate that although extra aerodynamic loss is generated by the geometric mutation of bifurcate segment, the bifurcate blade effectively restrains the migration of high-entropy secondary flow fluid in the shroud corner area, thus substantially decreasing the loss near endwall/corner, which remarkably promotes the aerodynamic performance, particularly under the condition of positive incidence angle. Moreover, the bifurcate blade skillfully remolds the pressure gradient on the blade surface, and promotes total pressure as well as velocity for the wake area that would be beneficial for the downstream rotor blade. With the introduction of key physical concepts and flow parameters of vortex/vorticity dynamics, such as boundary vorticity flux, vorticity vector, skin-friction vector and tangential pressure gradient, the physical root source and mechanism of gentle pressure gradient formation, wake flow structure being weakened, and flow separation reduction for the endwall and corner are further revealed.

First Report of Soybean Neocosmospora Stem Rot Caused by Neocosmospora vasinfecta var. vasinfecta in China

During October 2009, the occurrence of a disease on soybean (Glycine max) was observed in several fields in Boluo County and Zengcheng City, Guangdong Province. Top leaves of infected plants initially turned yellow and plants eventually were defoliated, while stems and roots became black and rotted. The stem lesions sometimes extended 10 to 15 cm upward from the soil surface. Orange-to-brown spherical fruiting bodies, which were very similar with those of the soybean red crown rot pathogen, scattered or congregated on the stem lesions. Plants with symptoms were sampled from fields. Fruiting bodies were excised from diseased tissues. Microscopic examination revealed that they were perithecia, globose to pyriform, ostiolate with a short neck, and measured 160 to 298 × 151 to 235 μm. Under gentle pressure, asci and ascospores were exuded from these perithecia. Asci were eight spored, narrowly cylindrical to clavate, thin walled, with a short stalk, and measured 58 to 124 μm long and 8 to 15 μm in diameter. Ascospores were uniseriately arranged, globose to ellipsoid, thick walled, one celled, hyaline to pale, and measured 14 to 17 × 8 to 12 μm. Isolation was made from stem tissues at the edge of disease lesions on potato dextrose agar (PDA) amended with streptomycin sulfate and incubated at 25°C. Mycelia were white and floccose. Conidia were cylindrical to oblong-ellipsoidal, hyaline, one celled, and measured 6 to 22 × 2 to 5 μm, aggregating in a slimy mass on the apex of the conidiogenous cell. Abundant orange-to-brown spherical perithecia were produced on the colony. Ascospores had walls with a rugose ornamentation that could be clearly seen under a scanning electron microscope. The fungus was identified as Neocosmospora vasinfecta var. vasinfecta (anamorph Acremonium sp.) (1). The internal transcribed spacer (ITS) region of rDNA of two isolates were amplified with universal primers ITS1/ITS4 and sequenced (GenBank Accession No. JF705861 and JF705862), and comparisons with GenBank accessions showed 99% similarity with N. vasinfecta strain Pec070 (Accession No. FJ940902) and strain NRRL22497 (Accession No. AY381142). Pathogenicity tests were conducted. Five, 3-week-old seedlings of soybean cv. Huaxia No. 3 planted in plastic pots (20 cm in diameter) were wounded with a needle at the base of the stem below the soil line and near the root system, and then inoculated by drenching the soil with a conidial suspension (105 per ml). Control plants were inoculated with sterile water. There were six replicates for each treatment. The treated plants were incubated at 25 ± 2°C in a greenhouse. All inoculated plants exhibited symptoms of leaf yellowing and black rot of stems and roots 3 weeks after inoculation. N. vasinfecta var. vasinfecta was reisolated from the diseased plants. All control plants remained healthy. To our knowledge, this is the first observation of Neocosmospora stem rot of soybean in China. The pathogen could pose a threat to soybean, which is a major crop in China. This disease has been previously reported in the United States though the anamorph of the pathogen has either not been identified or has been identified as a Cylindrocarpon sp. (2,4). This fungus is also associated with human infections (3). References: (1) P. F. Cannon and D. L. Hawksworth. Trans. Br. Mycol. Soc. 82:673, 1984. (2) F. A. Gray et al. Plant Dis. 64:321, 1980. (3) P. Manikandan et al. Med. Mycol. 46:279, 2008. (4) D. V. Phillips. Phytopathology 62:612, 1972.

Microsurgical removal of previously placed aneurysm clips and application of new clips for recurrent cerebral aneurysms

✓ A technique is described for removing previously placed aneurysm clips and applying new aneurysm clips for the treatment of regrown or reruptured cerebral aneurysms in patients more than 10 years after the original clipping of the aneurysm neck. The adherent tissue covering previously placed clips is cut just on and alongside the clips themselves using a small scalpel. Using the clip applicator, gentle pressure is applied to open the clip blade as little as possible. The aneurysm clip is carefully slid out along the line where the clip blade has resided, and a new aneurysm clip is applied. The procedure was successfully accomplished in four patients. Whereas three of these patients had an uneventful postoperative course, the remaining patient experienced transient right oculomotor nerve palsy and left-sided motor weakness. The present technique is a useful procedure for treatment of regrown or reruptured cerebral aneurysms occurring a significantly long time after initial clipping of an aneurysm neck.