A Potentiostat Readout Circuit with a Low-Noise and Mismatch-Tolerant Current Mirror Using Chopper Stabilization and Dynamic Element Matching for Electrochemical Sensors

This paper presents a potentiostat readout circuit with low-noise and mismatch-tolerant current mirror using chopper stabilization and dynamic element matching (DEM) for electrochemical sensors. Current-mode electrochemical sensors are widely used to detect the blood glucose and viruses in the diagnosis of various diseases such as diabetes, hyperlipidemia, and the H5N1 avian influenza virus (AIV). Low-noise and mismatch-tolerant characteristics are essential for sensing applications that require high reliability and high sensitivity. To achieve these characteristics, a proposed potentiostat readout circuit is implemented using the chopper stabilization scheme and the DEM technique. The proposed potentiostat readout circuit consists of a chopper-stabilized programmable gain transimpedance amplifier (TIA), gain-boosted cascode current mirror, and a control amplifier (CA). The chopper scheme, which is implemented in the TIA and CA, can reduce low frequency noise components, such as 1/f noise, and can obtain low-noise levels. The mismatch offsets of the cascode current mirror can be reduced by the DEM operation. The proposed current-mirror-based potentiostat readout circuit is designed using a standard 0.18 μm CMOS process and can measure the sensor current from 350 nA to 2.8 μA. The input-referred noise integrated from 0.1 Hz to 1 kHz is 21.7 pARMS, and the power consumption was 287.9 μW with a 1.8 V power supply.

A Symmetric Group Control Dynamic Element Matching Method Applied in High Resolution SAR ADCs for Biomedical Applications

Capacitor mismatch plays an important part in the spurious-free dynamic range (SFDR) performance of high-resolution successive approximation register (SAR) analog-to-digital converters (ADCs). This paper presents a symmetric group control dynamic element matching (SGCDEM) method aiming at enhancing SFDR of SAR ADCs applied in biomedical applications. The proposed scheme symmetrically divides the capacitor array into four sub-DACs, using quantization results corresponding to each sub-DAC as rotary control codes to symmetrically control the rotation of the capacitors. In order to improve the energy efficiency and save chip area, the proposed method replaces the pseudo-random number generator (PRNG) with quantization results of ADC as the rotary control code. Moreover, split rotator technology is applied in the proposed scheme to reduce the number of multiplexers (MUX) used in the rotator, which introduces a low logic depth. The proposed architecture has been implemented on a 12-bit SAR ADC model in MATLAB in order to verify its performances. After taking a standard deviation of 1% for the unit capacitance into consideration, this method achieves above 77.3[Formula: see text]dB SFDR, enabling to correct the SFDR by more than 23.6[Formula: see text]dB compared with the structure without DEM.