Research and Implementation of Self-Publishing Website Platforms for Universities Based on CMS

To update school websites, incorporating personality and ease of maintenance and management, the authors propose the use of a Content Management System (CMS). A CMS is a self-publishing Website platform for university information resources. The system has many features, such as self-service, fast station, self-service custom modules, dynamic replacement site style template, flexible adjustment of dynamic website contents and structures, search engine optimization (SEO) measures, and so forth. Each institution can customize according to their own information platform needs. A CMS greatly shortens the development cycle of the site and promotes the development of information tec hnology on campus.

Research and Implementation of Self-Publishing Website Platforms for Universities Based on CMS

To update school websites, incorporating personality and ease of maintenance and management, the authors propose the use of a Content Management System (CMS). A CMS is a self-publishing Website platform for university information resources. The system has many features, such as self-service, fast station, self-service custom modules, dynamic replacement site style template, flexible adjustment of dynamic website contents and structures, search engine optimization (SEO) measures, and so forth. Each institution can customize according to their own information platform needs. A CMS greatly shortens the development cycle of the site and promotes the development of information technology on campus.

Unusual pattern of single nucleotide polymorphism at the exuperantia2 locus of Drosophila pseudoobscura

We have investigated the pattern of DNA sequence variation at the exuperantia2 locus in Drosophila pseudoobscura. This adds to the increasing dataset of genetic variation in D. pseudoobscura, a useful model species for evolutionary genetic studies. The level of silent site nucleotide diversity and the divergence from an outgroup Drosophila miranda are comparable with those for other X-linked loci. One peculiar pattern at the exu2 locus of D. pseudoobscura is a complete linkage disequilibrium between two SNPs, one of which is a replacement site. As a result, there are two distinct haplotype groups in our dataset. Based upon the comparisons with the outgroup sequences from D. miranda and Drosophila persimilis, we show that the newly derived haplotype group has lower diversity than the ancestral haplotype group. The pattern of protein evolution at exu2 shows some deviation from the neutral model. Together, these and other characteristics of the exu2 locus suggest the action of selection on the pattern of SNP variation, consistent with a partial selective sweep associated with the newly derived haplotype.

Selection on Rapidly Evolving Proteins in the Arabidopsis Genome

Genes that have undergone positive or diversifying selection are likely to be associated with adaptive divergence between species. One indicator of adaptive selection at the molecular level is an excess of amino acid replacement fixed differences per replacement site relative to the number of synonymous fixed differences per synonymous site (ω = Ka/Ks). We used an evolutionary expressed sequence tag (EST) approach to estimate the distribution of ω among 304 orthologous loci between Arabidopsis thaliana and A. lyrata to identify genes potentially involved in the adaptive divergence between these two Brassicaceae species. We find that 14 of 304 genes (∼5%) have an estimated ω > 1 and are candidates for genes with increased selection intensities. Molecular population genetic analyses of 6 of these rapidly evolving protein loci indicate that, despite their high levels of between-species nonsynonymous divergence, these genes do not have elevated levels of intraspecific replacement polymorphisms compared to previously studied genes. A hierarchical Bayesian analysis of protein-coding region evolution within and between species also indicates that the selection intensities of these genes are elevated compared to previously studied A. thaliana nuclear loci.

Evidence for Selection at thefusedLocus ofDrosophila virilis

The genomic DNA sequence of a 2.4-kb region of the X-linked developmental gene fused was determined in 15 Drosophila virilis strains. One common replacement polymorphism is observed, where a negatively charged aspartic amino acid is replaced by the noncharged amino acid alanine. This replacement variant is located within the serine/threonine kinase domain of the fused gene and is present in ~50% of the sequences in our sample. Significant linkage disequilibrium is detected around this replacement site, although the fused gene is located in a region of the D. virilis X chromosome that seems to experience normal levels of recombination. In a 600-bp region around the replacement site, all eight alanine sequences are identical; of the six aspartic acid sequences, three are also identical. The occurrence of little or no variation within the aspartic acid and alanine haplotypes, coupled with the presence of several differences between them, is very unlikely under the usual equilibrium neutral model. Our results suggest that the fused alanine haplotypes have recently increased in frequency in the D. virilis population.